Please consider the following guidelines when booking this property:
This is not a hotel. It barely qualifies as a bed and breakfast. It's more like renting a room in someone's house.
While the staff were very polite, the overall quality of the place left much to be desired. We spent one night in the suite. This was of much better quality than the standard room we occupied, much higher price too.
The shower flow was a bare trickle and the temperature varied from cold to hot constantly, making for a frustrating experience. The pillows were of low quality. The walls were so thin we could hear the owners' phone ring as well as their conversations. Finally, some of the owners smoked and the smoke permeated the common areas. Not very pleasant. One plus is the location.
I would not return to Residenza Vespucci on future trips to Florence.