Discover a selection of 1,000 vacation rentals in San Luis Obispo Wine Country, US that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including pool and private pool. Prices start at C$ 162 per night, and house rentals and condo and apartment rentals are popular options for a stay in San Luis Obispo Wine Country. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — San Luis Obispo Wine Country
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How many vacation rentals are available around San Luis Obispo Wine Country?

Our 2022 vacation rental listings offer a large selection of 861 house rentals around San Luis Obispo Wine Country. From 531 house rentals to 221 condo and apartment rentals, find unique vacation rental for you to enjoy a memorable stay with your family and friends for a long holiday or a weekend break is on Vrbo.