Santo Spirito holiday rentals: flats & apartments & more

Discover a selection of 1,000 holiday rentals in Santo Spirito that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo holiday homes have the best amenities for hanging out with the people that matter most, including internet/WiFi and pool. Prices start at £ 57 per night, and flats & apartments and houses are popular options for a stay in Santo Spirito. Either way, you'll find a rental for everyone's needs.

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Find the best place to stay — Santo Spirito

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Stayed Mar 2021

Eccellente

We had a wonderful stay. It exceeded our expectations in every possible way. The central but peaceful location made it easy to walk around Firenze and the house itself was beautiful, spotlessly clean and with special touches. Upon arrival Niccolò was...

Stayed Aug 2020

Perfect location

Great 3 night stay with 9 and 12 year old. Clean, spacious apartment with loads of character.( no air conditioning due to age of apartment) Check in had all covid safety aspects covered: we felt very safe. Would definitely recommend if you want to ...

Stayed Jul 2020

The heart of Florence

We had a wonderful stay here - the location is absolutely perfect and right at the heart of Florence with a great view of the Ponte Vecchio - exactly as advertised. Communication with Luciano and Alina was really easy and we always had a quick respon...

Stayed Mar 2020

Perfect for us!

This was a perfect location with plenty of room and a very beautiful view. Although we didn’t have much contact with the owner, we could have if needed. Luckily, everything was provided and there were no issues. The little detached room was great for...

Stayed Feb 2020

Great location, pleasant apartment

Great location, easy walking distance to all major sights, but still quiet and peaceful. The apartment itself was clean, well-furnished and thoughtfully decorated. Nicky was very helpful. We were here in February, so did not have occasion to use the ...

Stayed Feb 2020

So much to love about this place

If I could give an extra five stars, I would. This apartment lives up to its name "Magic Terrace." The view and patio area are even more spectacular in person. It truly does have commanding views of the Duomo and bell tower, the Palazzo Vecchio and t...

Stayed Feb 2020

Perfect Spot for Exploring the City with Kids

This is an amazing space located in an ideal spot. The apartment is big and airy (yet, still manages to be cozy in winter) with plenty of space for a three year old to explore inside and out. We had a friend staying with us and having the separate be...

Stayed Dec 2019

Precioso apartamento

Apartamento muy bien decorado, baños modernos, cocina bien equipada, buena calefacción, apartamento impecable y una ubicación ideal. Lastima que no pudiéramos usar el cenador porque no tenía calefacción. Zona de difícil aparcamiento. Si volviese a Fl...

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Can I find a vacation rental around Santo Spirito?

Yes, our 2021 property listings offer a large selection of 1,045 vacation rentals near Santo Spirito. From 901 flats & apartments to 138 houses, find a unique house rental for you to enjoy a memorable stay with your family and friends. The best places to stay near Santo Spirito for a holiday or a weekend are on Vrbo.

Find the best place to stay — Santo Spirito

EXCLUSIVE SUITE with Amazing Terrace in the heart of Florence Ponte Vecchio

Romantic Apartment With Garden 2 Minutes' Walk From Pitti Palace

Beautiful apartment historical center Florence - 4/6

Historical Apartment From 16th Century

The view of Sangiorgio

Magic Terrace on Ponte Vecchio

Search 1,045 holiday rentals

Eccellente

Perfect location

The heart of Florence

Perfect for us!

Great location, pleasant apartment

So much to love about this place

Perfect Spot for Exploring the City with Kids

Precioso apartamento

Can I find a vacation rental around Santo Spirito?

Explore destinations around Santo Spirito

Santo Spirito holiday lettings

We found 1,045 holiday rentals — enter your dates for availability

Find the best place to stay — Santo Spirito

EXCLUSIVE SUITE with Amazing Terrace in the heart of Florence Ponte Vecchio

Romantic Apartment With Garden 2 Minutes' Walk From Pitti Palace

Beautiful apartment historical center Florence - 4/6

Historical Apartment From 16th Century

The view of Sangiorgio

Magic Terrace on Ponte Vecchio

Search 1,045 holiday rentals

Eccellente

Perfect location

The heart of Florence

Perfect for us!

Great location, pleasant apartment

So much to love about this place

Perfect Spot for Exploring the City with Kids

Precioso apartamento

Can I find a vacation rental around Santo Spirito?

Explore destinations around Santo Spirito