Discover a selection of more than 10,000 holiday rentals in South Carolina Lowcountry that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo holiday homes have the best amenities for hanging out with the people that matter most, including pool and internet/WiFi. Prices start at £ 121 per night, and houses and cottages are popular options for a stay in South Carolina Lowcountry. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — South Carolina Lowcountry
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Can I find a vacation rental around South Carolina Lowcountry?

Yes, our 2021 property listings offer a large selection of 11,118 vacation rentals near South Carolina Lowcountry. From 7,159 houses to 369 cottages, find the best place to stay with your family and friends to discover the South Carolina Lowcountry area.