Sant' Ambrogio holiday lettings
We found 2,758 holiday rentals — enter your dates for availability
Discover a selection of 210 apartments and other holiday rentals in Sant' Ambrogio that are perfect for your trip. Whether you're staying in a holiday rental with a group or just with your pet, you'll have the best amenities for spending time at your home away from home, which might include cable TV and a washer and dryer. You're sure to find a property to rent that has what everyone needs, including options that are accessible or non-smoking.
Holiday rentals with weekly discounts – Sant' Ambrogio
Showing deals for:29 Jan - 5 Feb

Exceptional
(35 reviews)
Apartment overlooking the Duomo
Florence
£1,128
for 7 nights, 1 apartment
£161 per night
includes taxes & fees

Exceptional
(16 reviews)
Steps to Ponte Vecchio.3BR/3BA+terrace w view of Pitti Palace
Florence
£2,721
for 7 nights, 1 apartment
£389 per night
includes taxes & fees

Exceptional
(113 reviews)
Beautiful and large apartment in great location, overlooking Ponte Vecchio
Florence
£2,580
for 7 nights, 1 apartment
£369 per night
includes taxes & fees

Exceptional
(45 reviews)
APARTMENT WITH 2-BEDROOM IN THE HISTORIC CENTER + PRIVATE PARKING
Florence
£851
for 7 nights, 1 apartment
£122 per night
includes taxes & fees

Exceptional
(52 reviews)
DANTE ROOF TERRACE HOUSE
Florence
£3,196
for 7 nights, 1 apartment
£457 per night
includes taxes & fees

Exceptional
(193 reviews)
Charming 3 bedroom Brand New Apartment in a Historic Building.
Florence
£1,851
for 7 nights, 1 apartment
£264 per night
includes taxes & fees

Exceptional
(119 reviews)
BRIGHT LOFT IN THE HEART OF FLORENCE, JUST A FEW STEPS FROM THE UFFIZI
Florence
£862
for 7 nights, 1 apartment
£123 per night
includes taxes & fees

Exceptional
(44 reviews)
Fortress Apartament with Parking
Florence
£1,189
for 7 nights, 1 apartment
£170 per night
includes taxes & fees

Exceptional
(64 reviews)
Spacious and charming apartment in the heart of Florence
Florence
£1,367
for 7 nights, 1 apartment
£195 per night
includes taxes & fees

Exceptional
(12 reviews)
Ponte Vecchio, Art & Design in Historic Palace
Florence
£2,793
for 7 nights, 1 apartment
£399 per night
includes taxes & fees

Exceptional
(40 reviews)
Apartment/ flat - Firenze
Florence
£910
for 7 nights, 1 apartment
£130 per night
includes taxes & fees

Exceptional
(136 reviews)
Romantic Apartment in the Hearth of Florence
Florence
£872
for 7 nights, 1 apartment
£125 per night
includes taxes & fees

Exceptional
(160 reviews)
Comfortable Apartment in Santa Maria Novella
Florence
£1,620
for 7 nights, 1 apartment
£231 per night
includes taxes & fees

Wonderful
(33 reviews)
Centrally located apartment, with all attractions within walking distance
Florence
£905
for 7 nights, 1 apartment
£129 per night
includes taxes & fees

Exceptional
(154 reviews)
A Few Steps From Duomo Cathedral and SMN train station
Florence
£1,142
for 7 nights, 1 apartment
£163 per night
includes taxes & fees

Exceptional
(118 reviews)
Cynthia's garden- Apartment with private garden
Florence
£1,946
for 7 nights, 1 apartment
£278 per night
includes taxes & fees

Exceptional
(147 reviews)
Just a few minutes from the Cathedral and the most beautiful Monuments in town
Florence
£470
for 7 nights, 1 apartment
£67 per night
includes taxes & fees

Exceptional
(62 reviews)
Located in the most chic area of Florence, trendy clubs near Ponte Vecchio
Florence
£1,591
for 7 nights, 1 apartment
£227 per night
includes taxes & fees

Exceptional
(21 reviews)
Bohémienne Penthouse in Santa Croce, Florence centre, Wi-Fi, Washers, AC
Florence
£2,022
for 7 nights, 1 apartment
£289 per night
includes taxes & fees

Exceptional
(34 reviews)
CasaGiardinoUno Simply Florence
Florence
£1,656
for 7 nights, 1 apartment
£237 per night
includes taxes & fees

Exceptional
(16 reviews)
LaCosta Apartment near Ponte Vecchio
Florence
£982
for 7 nights, 1 apartment
£140 per night
includes taxes & fees

Exceptional
(10 reviews)
A charming apartment in the shadow of Giotto's bell tower
Florence
£1,497
for 7 nights, 1 apartment
£214 per night
includes taxes & fees

Exceptional
(49 reviews)
Piazza Santa Croce, Uffizi, luxury apartment in a historic building
Florence
£1,268
for 7 nights, 1 apartment
£181 per night
includes taxes & fees

Exceptional
(124 reviews)
YOUR "BEAUTIFUL" VIEW ON FLORENCE!
Florence
£1,165
for 7 nights, 1 apartment
£166 per night
includes taxes & fees
Find spaces that suit your style
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Find the best place to stay - Sant' Ambrogio

Modern Murate View in Florence by Mmega
Sleeps 6 · 2 bedrooms · 2 bathrooms

Bright and wide, wonderful apt in the center of the city
Sleeps 8 · 5 bedrooms · 3 bathrooms

Palazzo dei Ciompi Suites
Sleeps 4 · 1 bedroom

Romantic Apartment in the Hearth of Florence
Sleeps 4 · 2 bedrooms · 1 bathroom

Buonarroti Apartment near the Cathedral, comfortable and romantic, free Wi-Fi, air conditioning
Sleeps 5 · 2 bedrooms · 2 bathrooms
Top rated rentals - Sant' Ambrogio

Family break
The apartment was lovely and spacious. Great location and the hosts were really friendly. Great communication before and during the stay. Only negative was daily cleaning is upon request which I didn’t realise and so we didnt get any clean towels.
Emma
Stayed Aug 2025

Beautiful rooms in a perf location
Beautiful rooms, spacious and a very well taken care of. There was a lovely little balcony to hear the evening swifts. Also in such a great location. Perfect stay!
Noelle
Stayed Jul 2022

Seddon’s and Ryder’s
Excellent location hotel and amenities were very good. Would recommend to friends
Eric
Stayed Jun 2019

Very enjoyable stay
Friendly and helpful staff, apartment in great condition and very clean, really good location. Everything was thought of to make our stay very enjoyable 😊
Omid
Stayed Feb 2020

Brilliant location and spacious glat
Couldn’t have asked for a better location. A stones throw from the cathedral and walkable from the train station. The flat has a mezzanine bedroom with twin beds over the main double room accessed by a narrow spiral staircase so if you have accessibility issues or small children it might not be suitable to use that floor. Easy check in and well equipped
Joanne W.
Stayed Oct 2024
- Peace of mindOur Book with Confidence Guarantee gives you 24/7 support
- More quality timeFrom booking to staying, the whole process is simple and enjoyable
- All the privacy of homeEnjoy full kitchens, pools, gardens and more
- More for lessMore space, more privacy, more amenities — more value
Frequently asked questions
How much does it cost to rent a holiday home in Sant' Ambrogio?
Prices for holiday rentals in Sant' Ambrogio vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're traveling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Sant' Ambrogio to more spacious homes. To get the best value, book early and take advantage of Vrbo's free rewards program.
Are there any discounts for Sant' Ambrogio holiday house rentals?
You can find great discounts on house rentals in Sant' Ambrogio on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
Are there any Sant' Ambrogio holiday rentals with parking?
Vrbo offers a wide selection of holiday rentals in Sant' Ambrogio with parking available—perfect for families or travellers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
Can I find long-stay holiday rentals in Sant' Ambrogio?
A long-stay holiday rental in Sant' Ambrogio is the best way to experience local living. Plus, you can make the most of long-stay discounts. Long-stay discounts are applied automatically when you enter your travel dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.
When is the best time to visit Sant' Ambrogio for a holiday rental?
The best time to visit Sant' Ambrogio for a holiday rental is in September, when the summer crowds begin to wane, yet the weather remains pleasantly warm. This month offers a delightful blend of mild temperatures, typically ranging from 15 to 25 degrees Celsius, ideal for exploring the picturesque Tuscan countryside and indulging in local cuisine at outdoor trattorias.The peak tourist season runs from July to September, attracting visitors eager to experience the region's stunning landscapes, historic sites, and vibrant festivals. During this time, you can enjoy leisurely strolls through olive groves, wine tastings in charming vineyards, and the enchanting atmosphere of the local markets. The early autumn light also enhances the beauty of the rolling hills, making it a stunning backdrop for photography.For those considering a more budget-friendly option, November can be an excellent choice. This month offers a quieter experience, allowing you to immerse yourself in the local culture without the hustle and bustle of peak season. You can savour the tranquillity of Sant' Ambrogio, witness the harvest season in full swing, and enjoy the region's culinary delights, such as truffles and hearty Tuscan stews.
How early should I book a Sant' Ambrogio holiday rental?
Book your Sant' Ambrogio holiday rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your holiday rental, the better the price.
*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
What are the top attractions in Sant' Ambrogio, Tuscany, Italy?
In Sant' Ambrogio, visitors can immerse themselves in the picturesque beauty and rich history of Tuscany. The charming village is home to the stunning Pieve di San Lorenzo, a beautiful Romanesque church that dates back to the 11th century, showcasing exquisite frescoes and a tranquil atmosphere. Nearby, the scenic vineyards and olive groves offer opportunities for wine tasting and exploring the local agricultural heritage, making it a delightful spot for gastronomy enthusiasts.The area is also close to the famous town of Fiesole, where you can discover ancient Roman ruins and enjoy spectacular views over Florence. For those seeking outdoor activities, the surrounding hills provide numerous hiking trails with breathtaking vistas of the Tuscan landscape.
Can I change or cancel my Sant' Ambrogio home rental booking on Vrbo?
To find Sant' Ambrogio holiday rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travellers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cosy cabin or a beach house, you can turn your space into a standout destination, become a host and let Vrbo handle the heavy lifting to help you thrive.
Earn a Premier Host badge by providing quick, reliable communication and consistently delivering outstanding guest experiences.
Are all fees included in the Sant' Ambrogio holiday rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.
What is VrboCare™ and how does it work?
Vrbo's mission is to help guests relax, reconnect, and enjoy precious time together. With VrboCare™, you can have peace of mind knowing you're protected and that if something goes wrong, we will do our best to make it right as applicable.
If a significant issue arises that your host can't resolve, we'll help you address it, find a similar property, or get your reservation refunded if applicable. That's our promise. If a home is significantly different than listed, we'll get you into a new space that meets your needs and makes it right, or if a host cancels before your stay, you have a dedicated support team to get you into a similar home as applicable.
What can I expect from Vrbo customer service and VrboCare™ support?
Your peace of mind is our priority. Whether you're planning your trip or have already finished your stay, VrboCare™ is here to support you every step of the way. For urgent situations, such as last-minute cancellations, booking issues, or potential fraud, Vrbo customer service is available 24/7 to support you every step of the way.
Vrbo also offers support via live chat through our Help Centre, where you can find helpful resources on bookings, payments, property management, and safety, making it easy to get instant answers to many common questions.
Can I plan a group trip on Vrbo?
Vrbo's Trip Planner makes organising group trips easy and stress-free. Whether you're planning with friends or coordinating a large group, you can collaborate in one place, save and share properties, vote on favorites, and build the perfect itinerary together.
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