Sant' Ambrogio holiday lettings
We found 2,738 holiday rentals — enter your dates for availability
Discover a selection of 204 apartments and other holiday rentals in Sant' Ambrogio that are perfect for your trip. Whether you're staying in a holiday rental with a group or just with your pet, you'll have the best amenities for spending time at your home away from home, which might include cable TV and a washer and dryer. You're sure to find a property to rent that has what everyone needs, including options that are accessible or non-smoking.
Holiday rentals with weekly discounts – Sant' Ambrogio
Showing deals for:4 Dec - 11 Dec

Exceptional
(16 reviews)
Steps to Ponte Vecchio.3BR/3BA+terrace w view of Pitti Palace
Florence
£2,855
for 7 nights, 1 apartment
£408 per night
includes taxes & fees

Exceptional
(45 reviews)
APARTMENT WITH 2-BEDROOM IN THE HISTORIC CENTER + PRIVATE PARKING
Florence
£901
for 7 nights, 1 apartment
£129 per night
includes taxes & fees

Exceptional
(135 reviews)
Wonderful city apartment with breath taking views over Florence.
Florence
£972
for 7 nights, 1 apartment
£139 per night
includes taxes & fees

Exceptional
(62 reviews)
Spacious and charming apartment in the heart of Florence
Florence
£1,824
for 7 nights, 1 apartment
£261 per night
includes taxes & fees

Exceptional
(93 reviews)
X-Large and luxury apartment in the old town! - All comfort -
Florence
£5,189
for 7 nights, 1 apartment
£741 per night
includes taxes & fees

Exceptional
(34 reviews)
Apartment overlooking the Duomo
Florence
£1,160
for 7 nights, 1 apartment
£166 per night
includes taxes & fees

Exceptional
(109 reviews)
BRIGHT LOFT IN THE HEART OF FLORENCE A FEW STEPS FROM UFFIZZI
Florence
£850
for 7 nights, 1 apartment
£121 per night
includes taxes & fees

Exceptional
(41 reviews)
Beautiful apartment sleeps in the city centre of Florence
Florence
£1,018
for 7 nights, 1 apartment
£145 per night
includes taxes & fees

Exceptional
(23 reviews)
Stunning view over Ponte Vecchio
Florence
£1,962
for 7 nights, 1 apartment
£280 per night
includes taxes & fees

Exceptional
(52 reviews)
DANTE ROOF TERRACE HOUSE
Florence
£2,782
for 7 nights, 1 apartment
£397 per night
includes taxes & fees

Exceptional
(150 reviews)
A Few Steps From Duomo Cathedral and SMN train station
Florence
£1,431
for 7 nights, 1 apartment
£204 per night
includes taxes & fees

Exceptional
(11 reviews)
Bright Apartment a few steps from Duomo and Train Station. Wifi, A/C, W&D
Florence
£1,444
for 7 nights, 1 apartment
£206 per night
includes taxes & fees

Exceptional
(87 reviews)
'Grande Pepi', Luxury Apartment in Florence Centre!(AC, Wifi,..)
Florence
£2,544
for 7 nights, 1 apartment
£363 per night
includes taxes & fees

Exceptional
(70 reviews)
Heart of Florence!!Penthouse with Terrace,Lift,breathtaking Views,near the Duomo
Florence
£1,754
for 7 nights, 1 apartment
£251 per night
includes taxes & fees

Exceptional
(111 reviews)
Beautiful and large apartment in great location, overlooking Ponte Vecchio
Florence
£2,352
for 7 nights, 1 apartment
£336 per night
includes taxes & fees

Exceptional
(57 reviews)
Located in the most chic area of Florence, trendy clubs near Ponte Vecchio
Florence
£1,385
for 7 nights, 1 apartment
£198 per night
includes taxes & fees

Exceptional
(68 reviews)
'Piccolo Pepi' - Luxury Apartment in the Heart of Florence!
Florence
£1,835
for 7 nights, 1 apartment
£262 per night
includes taxes & fees

Exceptional
(156 reviews)
Comfortable Apartment in Santa Maria Novella
Florence
£1,616
for 7 nights, 1 apartment
£231 per night
includes taxes & fees

Exceptional
(33 reviews)
CasaGiardinoUno Simply Florence
Florence
£1,846
for 7 nights, 1 apartment
£264 per night
includes taxes & fees

Exceptional
(102 reviews)
Il Battistero Apt - Luxury Apartments at 20 steps from Duomo; Elevator equipped.
Florence
£1,240
for 7 nights, 1 apartment
£177 per night
includes taxes & fees

Exceptional
(68 reviews)
Bardi Apartment, Stunning View Of Ponte Vecchio!
Florence
£2,276
for 7 nights, 1 apartment
£325 per night
includes taxes & fees

Exceptional
(184 reviews)
Apartment in a 13th Century palace in the heart of Florence
Florence
£1,713
for 7 nights, 1 apartment
£245 per night
includes taxes & fees

Exceptional
(42 reviews)
Fortress Apartament with Parking
Florence
£915
for 7 nights, 1 apartment
£131 per night
includes taxes & fees

Exceptional
(19 reviews)
Loft with a panoramic terrace overlooking the rooftops of Florence
Florence
£903
for 7 nights, 1 home
£129 per night
includes taxes & fees
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Find the best place to stay - Sant' Ambrogio

Modern Murate View in Florence by Mmega
Sleeps 6 · 2 bedrooms · 2 bathrooms

Bright and wide, wonderful apt in the center of the city
Sleeps 8 · 5 bedrooms · 3 bathrooms

Donati Tower Loggia: in the heart of Florence with spectacular views of the Duomo
Sleeps 3 · 1 bedroom · 1 bathroom

Fabulous 200sqm bright, new apartment walking distance to Duomo and city centre
Sleeps 12 · 5 bedrooms · 3 bathrooms
Top rated rentals - Sant' Ambrogio

Great location and comfort
Spacious and comfortable, easy ten minutes or so to The Duomo or Santa Croce, about 20 minutes to the station. Didn’t get to meet our host except by WhatsApp video, always available. Enjoyed Easter in Firenze, not too crowded and were able to attend the service in the Duomo including fireworks! Good walking tour with Alessandra
Dorothy F.
Stayed Apr 2025

The perfect place to stay
The apartment was everything we hoped it would be. We were particularly taken with the beautiful balcony, scented with lemon blossom and catching the morning sun, as we wanted somewhere peaceful to sit with a glass of wine in the evenings and this was perfect (even if the weather limited our use). The apartment is huge and well equipped, the bed in the main bedroom extremely comfortable (the only one we used). It was very easy to get into the centre of Flornce on foot (and return by bus when we were all walked out) and we loved the local area too, shopping in the Sant’Ambrogio market and eating in several extremely good local restaurants. Alessandro was an excellent host, communicating clearly before and during our stay, and we would love to return next time we come back to Florence.
Louise A.
Stayed Apr 2024

Peaceful oasis in a vibrant city
The photographs don't do the apartment justice - lovely decor, spacious and ingenious design. Located in very quiet square with excellent café and restaurants within a few yards. Elisabetta was very welcoming and has thought of everything.
Iqbal P.
Stayed Jul 2023

Lovely stay!
Great apartment and very good location!
Flavia R.
Stayed Jun 2022

Clean, well appointed, everything worked and a great location.
Sylvia was wonderful, very good tips for local restaurants, attractions, services etc. she was also very understanding when a rail strike forced us to change our plans. There have been some comments about this apartment being noisy. It is a pedestrian only street so noise is only voice and the odd delivery van, it’s not that bad. The location is great, we walked everywhere we wanted to go. It’s great being in the old section of Florence
Mark C.
Stayed Oct 2018
- Peace of mindOur Book with Confidence Guarantee gives you 24/7 support
- More quality timeFrom booking to staying, the whole process is simple and enjoyable
- All the privacy of homeEnjoy full kitchens, pools, gardens and more
- More for lessMore space, more privacy, more amenities — more value
Frequently asked questions
How much does it cost to rent a holiday home in Sant' Ambrogio?
Prices for holiday rentals in Sant' Ambrogio vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're traveling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Sant' Ambrogio to more spacious homes. To get the best value, book early and take advantage of Vrbo's free rewards program.
Are there any discounts for Sant' Ambrogio holiday house rentals?
You can find great discounts on house rentals in Sant' Ambrogio on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
Are there any Sant' Ambrogio holiday rentals with parking?
Vrbo offers a wide selection of holiday rentals in Sant' Ambrogio with parking available—perfect for families or travellers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
Can I find long-stay holiday rentals in Sant' Ambrogio?
A long-stay holiday rental in Sant' Ambrogio is the best way to experience local living. Plus, you can make the most of long-stay discounts. Long-stay discounts are applied automatically when you enter your travel dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.
When is the best time to visit Sant' Ambrogio for a holiday rental?
The best time to visit Sant' Ambrogio for a holiday rental is in September, when the summer crowds begin to wane, yet the weather remains pleasantly warm. This month offers a delightful blend of mild temperatures, typically ranging from 15 to 25 degrees Celsius, ideal for exploring the picturesque Tuscan countryside and indulging in local cuisine at outdoor trattorias.The peak tourist season runs from July to September, attracting visitors eager to experience the region's stunning landscapes, historic sites, and vibrant festivals. During this time, you can enjoy leisurely strolls through olive groves, wine tastings in charming vineyards, and the enchanting atmosphere of the local markets. The early autumn light also enhances the beauty of the rolling hills, making it a stunning backdrop for photography.For those considering a more budget-friendly option, November can be an excellent choice. This month offers a quieter experience, allowing you to immerse yourself in the local culture without the hustle and bustle of peak season. You can savour the tranquillity of Sant' Ambrogio, witness the harvest season in full swing, and enjoy the region's culinary delights, such as truffles and hearty Tuscan stews.
How early should I book a Sant' Ambrogio holiday rental?
Book your Sant' Ambrogio holiday rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your holiday rental, the better the price.
*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
What are the top attractions in Sant' Ambrogio, Tuscany, Italy?
In Sant' Ambrogio, visitors can immerse themselves in the picturesque beauty and rich history of Tuscany. The charming village is home to the stunning Pieve di San Lorenzo, a beautiful Romanesque church that dates back to the 11th century, showcasing exquisite frescoes and a tranquil atmosphere. Nearby, the scenic vineyards and olive groves offer opportunities for wine tasting and exploring the local agricultural heritage, making it a delightful spot for gastronomy enthusiasts.The area is also close to the famous town of Fiesole, where you can discover ancient Roman ruins and enjoy spectacular views over Florence. For those seeking outdoor activities, the surrounding hills provide numerous hiking trails with breathtaking vistas of the Tuscan landscape.
Can I change or cancel my Sant' Ambrogio home rental booking on Vrbo?
To find Sant' Ambrogio holiday rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travellers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cosy cabin or a beach house, you can turn your space into a standout destination, become a host and let Vrbo handle the heavy lifting to help you thrive.
Earn a Premier Host badge by providing quick, reliable communication and consistently delivering outstanding guest experiences.
Are all fees included in the Sant' Ambrogio holiday rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.
What is VrboCare™ and how does it work?
Vrbo's mission is to help guests relax, reconnect, and enjoy precious time together. With VrboCare™, you can have peace of mind knowing you're protected and that if something goes wrong, we will do our best to make it right as applicable.
If a significant issue arises that your host can't resolve, we'll help you address it, find a similar property, or get your reservation refunded if applicable. That's our promise. If a home is significantly different than listed, we'll get you into a new space that meets your needs and makes it right, or if a host cancels before your stay, you have a dedicated support team to get you into a similar home as applicable.
What can I expect from Vrbo customer service and VrboCare™ support?
Your peace of mind is our priority. Whether you're planning your trip or have already finished your stay, VrboCare™ is here to support you every step of the way. For urgent situations, such as last-minute cancellations, booking issues, or potential fraud, Vrbo customer service is available 24/7 to support you every step of the way.
Vrbo also offers support via live chat through our Help Centre, where you can find helpful resources on bookings, payments, property management, and safety, making it easy to get instant answers to many common questions.
Can I plan a group trip on Vrbo?
Vrbo's Trip Planner makes organising group trips easy and stress-free. Whether you're planning with friends or coordinating a large group, you can collaborate in one place, save and share properties, vote on favorites, and build the perfect itinerary together.
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