Where to begin? There are so many corners and sides to much-vaunted Italy that it can be hard to pinpoint the place to seek out your perfect guest house. From the glistening lakes of the north to the sun-baked beaches and pizza houses of the south, Tuscany's undulating vineyards to Amalfi's forget-me-not pastel towns, this guide can help you discover B&Bs in Italy that are bound to be something special.

A country bed and breakfast in Tuscany

Bed and breakfasts in Tuscany promise to whisk you away to quintessential Italy. This is a land of rolling vineyards and medieval hilltop towns. There are guest houses tucked on historic piazzas in little San Gimignano, and others fringing honey-stone palazzi in Montepulciano . But Tuscany is also the home of the agriturismo – earthy B&Bs in Italy that are located on working or converted farms. They are the places to go to sample country cooking fresh from the fields, and world-class wines, often with pools that have sweeping views of the Chianti Valley thrown in for good measure.

Monuments abound around B&Bs in Rome

As the great dome of St Peter's towers overhead, you'll navigate wiggling lanes that open onto the fantastical Baroque statues of the Trevi Fountain, or delve into ancient forums where Julius Caesar himself once trod. Welcome to the Eternal City, a metropolis of buzzing trattoria and church-rimmed piazzas. There are B&Bs in Rome that can get you really close to the colosseum, too. Look for them in the immersive La Trastevere neighborhood – a perfect choice for romantic types – or around the large blocs north of Termini station.

Steal someone's heart with bed and breakfasts in Venice

Venice is one for the lovers. Why? Well there's nothing quite as romantic as a room that opens up onto visions of the Grand Canal. There's nothing quite like clinking a bubbling prosecco by the arched Rialto Bridge. And this is the home of the water gondola, which you can ride through narrow canals as the scents of risotto and lasagna waft out from the eateries above. If you're after somewhere a little quieter, consider searching for your B&B in Italy in districts like Murano or the beachside Lido.

Culture vultures assemble in B&Bs in Florence

Masterworks by Titian, Michelangelo, and Botticelli burst from the legendary exhibits of the Uffizi Gallery in central Florence, while the yellow-painted outline of the Ponte Vecchio bridge crosses the smooth-flowing Arno, and the proud Duomo looms high with its marble-inlayed walls. Yep, there are loads of reasons this is considered one of the most handsome cities in all of Europe. You can even get B&Bs housed in medieval palazzi with flurries of Renaissance art decorating their suites.

B&Bs in Italy's lakes and Alps

Venture to the far north of Italy and it's not long before the rolling vineyards and cypress-topped farms are replaced by the crumpled peaks of the Prealps. That soft range of wooded ridges starts in the enchanting medieval city of Bergamo, soon giving way to the grand villas of Lake Como, or – if you enjoy going off-the-beaten-path – the romantic town of Lovere in Lake Iseo. Go even further north and B&Bs in Italy turn into Swiss-style ski chalets, with wood-framed architecture, indoor swimming pools, and saunas, all on the doorstep of resorts like Val Gardena and Cervinia.

Bed and breakfasts in Sicily – an isle like no other

If you're looking for sun, sea, and sand, Sicily could be the perfect region to seek out B&Bs in Italy. On the southern end of the country, it's an island all to itself, ringed by rugged cliffs, salt pans, and white-tinted beaches. Syracuse is a top place to aim for – the guest houses there cling to the ancient center of Ortigia, which has waterside seafood grills and places where you can dive straight into the Med. Catania, meanwhile, has grit and moxie, with buzzing street-food bazaars and Baroque churches in the shadow of Mount Etna.

Somewhere special to stay on the Amalfi Coast

Planning a honeymoon to Italy? Don't overlook the B&Bs in Italy's Amalfi Coast region. Designated a UNESCO World Heritage Site, the area is jaw-droppingly beautiful. It starts south of Naples and wiggles around a peninsula where cascading lemon orchards and wine farms roll to meet a deep-blue sea. There are some sumptuous clifftop villas for rent in towns like Amalfi or Erchie, but real jet setters will zero in on Capri – the old Roman escape island that has grottoes and spas across the water.