Discover a selection of 42 vacation rentals in Santa Cruz, BO that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $25 per night, and houses and condos are popular options for a stay in Santa Cruz. Either way, you'll find a rental for everyone's needs.
Destination guide

Book a vacation rental for your Santa Cruz getaway

Enjoy the cathedral and other features of Santa Cruz. Renowned for its shopping, cafés and zoo, this city welcomes all visitors. Many rental homes come with outdoor spaces, separate dining areas and full kitchens, perfect if you want to enjoy some home-cooked meals.


Activities and attractions in Santa Cruz

Are you hoping to discover top things to see and do while you're in the area? Venture out of your cozy vacation rental and check out everything that makes Santa Cruz a fun place to get away. Here are some of the most popular attractions to explore, all within 30 miles (48.2 km) of the city center:

  • Santa Cruz Zoo (1.7 mi / 2.8 km)
  • AquaLand (9.9 mi / 16 km)
Natural features

Exploring the natural features in Santa Cruz

Whether you're an active traveler or just want to take in the scenery, Santa Cruz is a great place to get outside. These are a few of the area's most stunning natural features, all within 30 miles (48.2 km) of the city center:

  • Arenal Park (0.4 mi / 0.7 km)
  • Guembe Biocenter (4.6 mi / 7.4 km)
  • Municipal Botanical Garden of Santa Cruz (7.6 mi / 12.2 km)
  • Lomas de Arena Regional Park (10.7 mi / 17.1 km)
How to get there

How to get to and around Santa Cruz

The nearest airport is in Santa Cruz (VVI-Viru Viru Intl.), located 9.8 mi (15.8 km) from the city center.

How many vacation rentals are available around Santa Cruz, BO?

Our 2020 property listings offer a large selection of 42 vacation rentals around Santa Cruz. From 7 house rentals to 29 condo and apartment rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What are the most popular destinations to visit in Santa Cruz?

There are many lovely places to stay for a holiday trip or just for a weekend in Santa Cruz. From Vrbo travelers, the top most popular destinations to visit are:

  • Santa Cruz: 39 vacation rentals
  • Plaza 24 de Septiembre: 39 vacation rentals
  • AquaLand: 39 vacation rentals
  • Andrés Ibáñez Province: 39 vacation rentals
  • Sacred Art Museum: 39 vacation rentals

And Vrbo offers you the chance to discover many other popular destinations in Santa Cruz! Please use our search bar to access the selection of vacation rentals available in other popular destinations.

Near which points of interest can I spend my holidays in Santa Cruz?

Vrbo offers a large selection of rentals near lovely places in Santa Cruz. From Vrbo travelers, the top most popular points of interest to stay for a holiday trip or just for a weekend are:

  • Plaza 24 de Septiembre: 39 rentals
  • AquaLand: 39 rentals
  • Sacred Art Museum: 39 rentals
  • Guembe Biocenter: 39 rentals
  • Santa Cruz Zoo: 39 rentals

But there are many other points of interest around Santa Cruz listed on Vrbo where you can find your place to stay. Just write your wanted destination in our search bar and have a look at our selection.