Discover a selection of 207 vacation rentals in Panama City, PA that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $63 per night, and houses and condos are popular options for a stay in Panama City. Either way, you'll find a rental for everyone's needs.
Top rated rentals — Panama City
Destination guide

Experience Panama City in vacation home rentals

There's everything from swish high-rise condos on well-to-do Balboa Avenue to Pacific-side Panama City vacation rentals overlooking the sands of Playa Bonita, all ready to offer you a base in one of Central America's most happening capitals. Here, days of wandering between the brick-chipped cathedrals of the UNESCO-tagged, pirate-trodden Casco Viejo merge with evenings of mojito drinking through the neon-lit cantinas of Calle Uruguay. You can see the wonders of the Panama Canal, too, and while away weekends on soft-sanded tropical islands where three-toed sloths are your only compadres.

Things to do

Places to visit near Panama City vacation rentals

Panama City's Casco Viejo is like a living museum. UNESCO has tagged it as a World Heritage Site for its wealth of age-stained churches, palm-shaded plazas and centuries-old palazzos. It's also, perhaps a little curiously, home to the Panama Canal Museum. Go there for an introduction to the engineering feats that cut the mighty waterway through the heart of Central America before striking out to see the Panama Canal itself – the views from the famous Miraflores Locks are the perfect place to begin.


Things to do near Panama City vacation homes

Panama City vacation rentals are a ticket to a buzzing metropolis that's home to big business and brilliant historical relics. Guided tours of old pirate-conquered forts and Spanish citadels are a great way to while away your mornings, and afternoons of beach lazing and strutting the avenues with a cold papaya-pineapple juice in hand seems like a good way to top it all off. Boat cruises up and down the famous canals are a must, too, but not before you've shimmied the night away in the rambunctious bars of the Casco Viejo and beyond – think subterranean discos and mojito-doused cantinas.


Best time to travel to Panama City vacation homes

Constant warmth that sees the thermometers hover around the 85-90 mark makes Panama City a great place to visit, no matter the month. That said, there's a distinct difference between the drier and wetter parts of the year. The latter come with June, July, August and September, and can have prolonged showers all over the Pacific coast – don't worry though, the museums, canal locks, and wild bars don't shut for business. For less precipitation, you should seek out Panama City vacation rentals between December and April.

Natural features

Sloths and seas in Panama City

Panama City sits on the south coast of the nation as it wiggles in an S-bend at the start of Central America. You won't have to travel far to catch a glimpse of the lush rainforests that have made Panama such a famous ecotourist destination. Head north along the great canal to hit the reserves of Camino de Cruces National Park, where the coast-to-coast Camino de Cruces trail weaves through the jungles and offers sightings of toucans and sloths. In the other direction is the Pacific, hiding paradisiacal islands like Taboga _ think white-sand beaches, whale watching, and palm forests.

How to get there

Transportation options to and around Panama City

Fly into Panama City (PAC-Marcos A. Gelabert Intl.), the closest airport, located 2.5 mi (4 km) from the city center. If you're unable to find a flight that fits your schedule, you might consider flying into Balboa (BLB-Panama Pacifico Intl.), which is 6.3 mi (10.1 km) away.

If you'd rather travel by train, you can make your way to Panama City Passenger Station. It's easy to get around Panama City by jumping on the metro at Iglesia del Carmen Station, Santo Tomas Station or Estación Lotería.

Family friendly

Family fun near Panama City vacation rentals

Kids will love the array of attractions in Panama City. Vacation homes are available near places like Metropolitan Natural Park, a wildlife refuge with nature trails, picnic areas, lookout points, and diverse wildlife, and Biomuseo, a whimsical museum with galleries on Panama’s biodiversity. You could also visit Ancon Hill, a tall hill overlooking the city with a nature reserve housing sloths, deer, and other wildlife.

Good for couples

Couple's retreat near Panama City vacation homes

Panama City is an ideal destination for a couple’s retreat. Vacation homes are available near places like Parque Municipal Summit, a botanical garden with a variety of tropical plants and a zoo with unique wildlife, and Chagres National Park, a massive natural area near the canal with dense tropical rainforests. You could also visit the National Theatre of Panama, an entertainment venue with a frescoed ceiling and dance, music, and play performances.

How many vacation rentals are available around Panama City, PA?

Our 2021 property listings offer a large selection of 207 vacation rentals around Panama City. From 36 house rentals to 161 condo and apartment rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What is the best area to stay when traveling to Panama City?

Whether you're traveling with family or friends, here are the areas with the largest selection of vacation rentals for a holiday trip or just for a weekend in Panama City:

  • Campo Alegre: 46 vacation rentals
  • Casco Viejo: 26 vacation rentals
  • Obarrio: 40 vacation rentals
  • Marbella: 39 vacation rentals
  • El Cangrejo: 213 vacation rentals

For other neighborhoods, please use our search bar to access the selection of vacation rentals available.

What are the popular point of interests near where I can stay when traveling to Panama City?

Vrbo offers a large selection of vacation rentals near lovely places in Panama City. From Vrbo travelers, the top most popular points of interest to stay for a holiday trip or just for a weekend are:

  • El Cangrejo: 213 vacation rentals
  • Panama Viejo: 212 vacation rentals
  • Ancon Hill: 198 vacation rentals
  • Metropolitan Cathedral of Panama: 212 vacation rentals
  • Interoceanic Canal Museum: 212 vacation rentals

But there are many other points of interest around Panama City listed on Vrbo where you can find your place to stay. Please use our search bar to access the selection of vacation rentals available near the point of interest of your choice.

Can I rent Houses in Panama City?

Yes, of course. Vrbo has 36 Houses in Panama City. Our other popular types of vacation rentals in Panama City include:

  • Condos/Apartments: 161 rentals available
  • Studios: 125 rentals available
  • Hotels: 3 rentals available

But you can also enjoy a great stay in one of our other vacation rentals including Bed & breakfasts and more.

Can I find a vacation rental with pool in Panama City?

Yes, you can select your preferred vacation rental with pool among our 145 vacation rentals with pool available in Panama City. Please use our search bar to access the selection of vacation rentals available.

Explore destinations around Panama City

Campo Alegre
46 vacation rentals
Casco Viejo
26 vacation rentals
40 vacation rentals
39 vacation rentals
El Cangrejo
213 vacation rentals
Costa del Este
23 vacation rentals