Discover a selection of 1,000 vacation rentals in Santo Spirito, Florence that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including WiFi and air conditioning. Prices start at $60 per night, and houses and condos are popular options for a stay in Santo Spirito. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — Santo Spirito
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What are the top vacation rentals in or near Santo Spirito?

Whether you're seeking an intimate retreat for you and your sweetheart or a sprawling house to fit family and friends, you'll find some top vacation rentals in and around Santo Spirito. Here are a couple to get you thinking:

  • Around 0.1 miles from the center of Santo Spirito, you'll find it hard to resist "Elegant Apartment With Garden 10 'from Pontevecchio". It has 2 bedrooms and a range of conveniences like children's games and a living room.
  • Another top choice is "Amazing Views Of Ponte Vecchio And Uffizi", which is around 1 mile from Santo Spirito. Featuring 1 bedroom, towels and off-street parking options, it has everything you need to keep you content and comfortable.

For even more great options, use the search bar at the top of the page to find the perfect Santo Spirito vacation rental for you.

What are the top-rated vacation rentals for weekend getaways in or near Santo Spirito?

Your Monday to Friday will be much easier to endure if you've got something awesome lined up for the weekend. Give yourself something fun to look forward to by reserving one of these top weekend getaways in or near Santo Spirito:

  • Book a couple of nights or longer at "Bellosguardo / San Francesco Di Paola With Private Garden", around 0.1 miles to the southeast of Santo Spirito, and you've got yourself the ultimate weekend break. You'll have natural attractions like Museo del Tessuto and Boboli Gardens close by and amenities like coffee and tea making facilities and nearby museums at your disposal.
  • "Garden House From The 15th Century Near The Ponte Vecchio" is also perfect for a whirlwind getaway. Around 1 mile to the east of Santo Spirito, this vacation rental offers amenities like a fridge and off-street parking options. Museo Stibbert and Corsini Park should be on your itinerary if you stay here.

Can I find studio apartments for rent in and around Santo Spirito?

Studio apartments are a simple yet stylish choice, ideally suited for traveling couples or solo stays. Spend your days getting acquainted with the area and your nights relaxing in your cozy hideaway. These vacation rentals in or near Santo Spirito will tick all the boxes:

  • One of our favorite properties is "Amazing Views Of Ponte Vecchio And Uffizi". Book a few nights or longer at this popular stay and you'll have access to nearby museums and air conditioning.
  • "Typical Florentine Dwelling Within The Walls Of The City Near The Boboli Gardens" is another wonderful stay, providing all you could need for a heavenly Santo Spirito retreat. Convenient amenities here include an oven and a nearby laundromat.

Can I find short term rentals in or near Santo Spirito?

Whether you're looking for a cozy cottage or a house with enough space for the family, you'll find the perfect place on Vrbo. Enjoy some downtime at one of these getaways in or near Santo Spirito:

  • Close to the center of Santo Spirito, "Typical Florentine Dwelling Within The Walls Of The City Near The Boboli Gardens" rolls out the welcome mat for short-term guests. When you're not relaxing in your cozy digs, get out and discover all the cool stuff around you.
  • Alternatively, spend a few relaxing nights at "Great Accomodation In The Florence". This comfy, conveniently located property makes it easy to explore the area's sights.

What are the best romantic weekend getaways in or near Santo Spirito?

Nothing says "I love you" like planning a romantic weekend together. If you want to spend a couple of relaxing evenings away with your sweetheart, we've got some romantic getaways in and around Santo Spirito that will get your heart racing:

  • Slip away on Friday afternoon for a few passion-filled nights at "Elegant Apartment With Garden 10 'from Pontevecchio". Roughly 0.1 miles from Santo Spirito, this property comes with lots of nice touches, including winery tours and air conditioning.
  • "Amazing Views Of Ponte Vecchio And Uffizi" is another wonderful option that'll impress. It's approximately 1 mile from Santo Spirito and has air conditioning and shopping facilities.

What are the best large group vacation rentals in or near Santo Spirito?

Share your trip and have more fun. Whether you're organizing an adventurous getaway with buddies or a big family gathering, you'll have your choice of large group vacation rentals in and near Santo Spirito:

  • Offering comfort, space and privacy, you'll get your guests' stamp of approval at "Great Flat In The Heart Of Florence". Up to 14 people can be accommodated at this property which has 4 bedrooms, a kitchen and off-street parking options. This top pick is around 1 mile to the east of Santo Spirito.
  • Invite up to 12 of your dearest friends to "Pitti Historical Home - Phh" and fill the place with love and laughter. This option has 4 bedrooms and is around 1 mile to the east of central Santo Spirito. It's packed with features to keep large groups occupied, such as a firepit and a kitchen.

What are the best houses for rent with a pool in or near Santo Spirito?

Having access to a pool is always a nice bonus when you're on vacation, especially if you're taking the kids. Splash the days away at one of these houses with a pool in or near Santo Spirito:

  • Make pool day every day at "Garden House From The 15th Century Near The Ponte Vecchio". A DVD player and coffee and tea making facilities are a couple of the other amenities that help make this place a winner.
  • "Silent And Elegant House In The San Frediano District Of Florence" is another highly rated option. After you've enjoyed a relaxing dip with the fam, make use of other conveniences like a TV and a kitchen.

What are the best large family vacation rentals in or near Santo Spirito?

A family getaway should be about spending some quality time together and sharing new experiences. If you're seeking a home away from home that's big enough for all the gang, browse through some of our large family vacation rentals in and around Santo Spirito:

  • Suitable for up to 8 guests over 3 bedrooms, "Garden House From The 15th Century Near The Ponte Vecchio" is a popular choice with larger families. It comes with a separate dining area and coffee and tea making facilities and is around 1 mile east of Santo Spirito.
  • Another fantastic option is "Casagiorgio A Stone's Throw From The Historic Center". It's about 0.1 miles to the east of Santo Spirito, has 3 bedrooms and accommodates up to 7 guests. A TV and childrens activities are just two of the many conveniences on offer here.

Are there one-bedroom vacation rentals in or near Santo Spirito?

Often situated in prime positions due to their compact size, a one-bedroom rental is the perfect solution if it's just the two of you. Check out Vrbo's range in or near Santo Spirito:

  • Take a peek at "Amazing Views Of Ponte Vecchio And Uffizi", a fabulous centrally located one-bedroom vacation property. A kitchen and a nearby waterfront are just two of the amenities here.
  • "Amazing Beach Front Villa With Pool" is another comfy one-bedroom escape also close to the center. When you're not out discovering the surrounds, make use of an ocean view and a water park.

Can I find two-bedroom vacation rentals in or near Santo Spirito?

It's easy to arrange a fantastic vacation with Vrbo. Whether you're looking for a cozy cabin or a cool apartment, you'll find terrific two-bedroom options in or near Santo Spirito: Here are a couple of our favorites:

  • Heading up our list is "Elegant Apartment With Garden 10 'from Pontevecchio". This two-bedroom delight has handy amenities like a garden and a water view. Visit Santo Spirito's various attractions from this comfortable pad.
  • "Silent And Elegant House In The San Frediano District Of Florence" is another lovely two-bedroom retreat. It comes with a kitchen, an oven and lots more.