We found 7,258 vacation rentals — enter your dates for availability
Discover a selection of private vacation rentals near Sistine Chapel that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, vacation rentals have the amenities you need and want for your stay, which might include a pool and a washer and dryer. No matter what you're looking for, you'll be sure to find a rental for everyone's needs, including a place that is accessible or non-smoking.