Photo by Linda Cronan
Medical Center District vacation rentals
We found 213 vacation rentals — enter your dates for availability
Find the perfect place for your stay in Medical Center District by choosing from 48 houses, 35 apartments, and other vacation rentals. Vacation rentals offer the amenities you expect for your stay with friends, family, or just your pet, like WiFi and a washer and dryer. You're sure to find a rental to meet everyone's needs, including places that are non-smoking or accessible.
Find spaces that suit your style
House
Condo/Apartment
Find the best place to stay - Medical Center District

Vintage Home, Minutes from Medical Center, Sea World, and Downtown San Antonio
Sleeps 6 · 3 bedrooms · 2 bathrooms
10 out of 10
exceptional
(96 reviews)
Top rated rentals - Medical Center District

Quick trip to SA
10 out of 10
exceptional
(4 reviews)
- Peace of mindOur Book with Confidence guarantee gives you 24/7 support
- All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
- More for lessMore space, more privacy, more amenities — more value