Discover a selection of 49 vacation rentals in Sanibel that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and private pools. Prices start at $159 per night, and houses and condos are popular options for a stay in Sanibel. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — Sanibel
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How many vacation rentals are available around Sanibel?

Our 2021 property listings offer a large selection of 49 vacation rentals around Sanibel. From 2 house rentals to 47 condo and apartment rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.