Discover a selection of 500 vacation rentals in San Luis Obispo, CA that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $100 per night, and houses and cabins are popular options for a stay in San Luis Obispo. Either way, you'll find a rental for everyone's needs.
Top rated rentals — San Luis Obispo
Destination guide

Ocean breezes and a whiff of farm in San Luis Obispo

It's simply San Luis or SLO to those in the know. A place so green and clean that "you can even smell the cows," sang comic musician Weird Al Yankovic, once a student here at California Polytechnic. From a San Luis Obispo vacation rental, grab a drink at landmark Madonna Inn so you can gawk at the eclectic architecture and gaudy furnishings. History buffs can happily stroll the Mission grounds and study its museum's 18th-century artifacts. Beach attractions and winery tours are nearby, and outdoor adventures abound in the foothills.

Things to do

Does chewing gum lose its flavor on the wall overnight?

It all began in 1772, when Junipero Serra founded the Mission San Luis Obispo de Tolosa. It's an active church, but travelers can stroll the grounds and tour the museum. Cross Mission Plaza for a peek at Bubblegum Alley—yes, the walls are stuck with thousands of wads of chewed gum. In and out of town, you'll find wineries and craft breweries. Kids enjoy the Creek Walk and Children's Museum. A San Luis Obispo vacation rental is a good base for driving up the coast to tour Hearst Castle at San Simeon.


Take it SLO on the way to San Luis Obispo

Catch a taste—literally—of San Luis Obispo's main industry, agriculture, any Thursday when the farmers' market fills 6 blocks of Higuera Street downtown with fresh produce, flowers, barbecues, and family-friendly entertainers. Head to Avila Beach to tour historic 1890 Point San Luis Lighthouse and see its eye-popping vista. The peaks around SLO offer hiking and biking, guided or not. Some dozen wineries in the valley have tastings. A thriving theater scene includes the Cal Poly campus's performing arts center.


In San Luis Obispo, you can usually expect the usual

Pack those shorts and T-shirts and plan on outdoor activities, even if that morning marine fog makes the day seem iffy. Like much of coastal Southern California, San Luis Obispo has a cool, Mediterranean climate—dry in the summer, with daytimes in the 70s, and slightly wetter and cooler in winter. But be prepared for extremes, such as a scorching, 100-degree-plus stretch anytime from April through October, a 90-degree day in January, or a dip below zero for a day or so between November and February.

Natural features

In a happy spot between L.A. and Monterey

San Luis lies in a broad valley surrounded by peaks—of which the tallest, Bishop Peak, and others are open for hikes that reveal stunning views. A San Luis Obispo vacation rental is a rewarding stopover for coastal travelers midway between L.A. and Monterey. It's only 11 miles from the coast, so the beach is an easy diversion from town sights. Follow the coast north to Morro Bay to view sea otters and herons, try Piedras Blancas for elephant seals, or head south to Pismo Beach between October and February to glimpse migrating butterflies.

How to get there

Traveling to and around San Luis Obispo

Fly into San Luis Obispo, CA (SBP-San Luis Obispo County Regional), the closest airport, located 3 mi (4.9 km) from the city center. If you can't find a flight that's convenient for your trip, you might consider flying into Santa Maria, CA (SMX-Santa Maria Public), which is 28.8 mi (46.4 km) away.

If you prefer train travel, the main station serving the city is San Luis Obispo Station.

How many vacation rentals are available around San Luis Obispo, CA?

Our 2021 property listings offer a large selection of 662 vacation rentals around San Luis Obispo. From 371 house rentals to 31 cabin rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What are the popular point of interests near where I can stay when traveling to San Luis Obispo?

Vrbo offers a large selection of vacation rentals near lovely places in San Luis Obispo. From Vrbo travelers, the top most popular points of interest to stay for a holiday trip or just for a weekend are:

  • San Luis Obispo Station: 984 vacation rentals
  • Bishop Peak Trail: 1,012 vacation rentals
  • San Luis Obispo Children's Museum: 987 vacation rentals
  • Emerson Park: 982 vacation rentals
  • San Luis Obispo Museum of Art: 987 vacation rentals

But there are many other points of interest around San Luis Obispo listed on Vrbo where you can find your place to stay. Please use our search bar to access the selection of vacation rentals available near the point of interest of your choice.

Can I rent Houses in San Luis Obispo?

Yes, of course. Vrbo has 371 Houses in San Luis Obispo. Our other popular types of vacation rentals in San Luis Obispo include:

  • Cabins: 31 rentals available
  • Cottages: 31 rentals available
  • Condos/Apartments: 216 rentals available

But you can also enjoy a great stay in one of our other vacation rentals including Bungalows and more.

Can I find a vacation rental with pool in San Luis Obispo?

Yes, you can select your preferred vacation rental with pool among our 80 vacation rentals with pool available in San Luis Obispo. Please use our search bar to access the selection of vacation rentals available.

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