San Luis Obispo, CA Vacation Rentals: house rentals & more

Discover a selection of 1,000 vacation rentals in San Luis Obispo, CA that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $77 per night, and houses and cabins are popular options for a stay in San Luis Obispo. Either way, you'll find a rental for everyone's needs.

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Find the best place to stay — San Luis Obispo

Search 823 vacation rentals

Stayed Apr 2021

Good Experience!

This was a really cool experience. I loved the aesthetic of the Butler hotel and the close proximity to downtown. However, when we went to check in the email from the property manager didn’t have our room number on it (lol) so we had to try all the d...

Stayed Apr 2021

Great getaway

My family really enjoyed their stay in the Irish Hills house. Ryan was awesome and easy going. My kids loved exploring the property and playing with Bourbon, Cider, Walter and the chickens. So many fun local places to check out and of course a short ...

Stayed Apr 2021

Best view one can ever think of!

We had such a wonderful time at SLO lodge. The views from the deck overlooking the lake and mountains were amazingly beautiful. The host, Leslie is super accommodating and sweet and very responsive. We had a warm welcome and explained everything abou...

Stayed Apr 2021

Great vacation stay

Stayed at Villa Eduardo with family and friends for my birthday weekend. The house was very clean and in a great location! We were walking distance to the store and a short drive to the beach and restaurants! The house and rooms were very spacious an...

Stayed Mar 2021

Wonderful place!

We really enjoyed this spot. It was easy to get to downtown SLO as well as Montana de Oro and Morro Bay. Our teens loved the foosball table and huge TV. We found the kitchen well appointed for cooking and Kathleen was a very responsive host. Would de...

Stayed Mar 2021

A Little Slice of Heaven

The epitome of tranquility. I can't speak highly enough of the little red farmhouse and the ranch property was even more beautiful than the listing photos. We were fortunate to have spectacular Spring weather and took full advantage by sitting on the...

Stayed Mar 2021

Breathtaking

We had such a wonderful time at the ranch. The views are something out of a magazine. So much to explore and see. Darla is a sweet gem and was very helpful with anything we needed. We will definitely be coming back and bringing more friends. Till nex...

Stayed Mar 2021

Fantastic Escape

My family of 5 and 2 dogs had an amazing time at this place. We loved all the animals. Bourbon and Cider were fast friends with our dogs and kids. My sons loved feeding the chickens, tortoise, and fish and we loved the fresh eggs! The house’s amazing...

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Destination guide

Ocean breezes and a whiff of farm in San Luis Obispo

It's simply San Luis or SLO to those in the know. A place so green and clean that "you can even smell the cows," sang comic musician Weird Al Yankovic, once a student here at California Polytechnic. From a San Luis Obispo vacation rental, grab a drink at landmark Madonna Inn so you can gawk at the eclectic architecture and gaudy furnishings. History buffs can happily stroll the Mission grounds and study its museum's 18th-century artifacts. Beach attractions and winery tours are nearby, and outdoor adventures abound in the foothills.

Things to do

Does chewing gum lose its flavor on the wall overnight?

It all began in 1772, when Junipero Serra founded the Mission San Luis Obispo de Tolosa. It's an active church, but travelers can stroll the grounds and tour the museum. Cross Mission Plaza for a peek at Bubblegum Alley—yes, the walls are stuck with thousands of wads of chewed gum. In and out of town, you'll find wineries and craft breweries. Kids enjoy the Creek Walk and Children's Museum. A San Luis Obispo vacation rental is a good base for driving up the coast to tour Hearst Castle at San Simeon.

Activities

Take it SLO on the way to San Luis Obispo

Catch a taste—literally—of San Luis Obispo's main industry, agriculture, any Thursday when the farmers' market fills 6 blocks of Higuera Street downtown with fresh produce, flowers, barbecues, and family-friendly entertainers. Head to Avila Beach to tour historic 1890 Point San Luis Lighthouse and see its eye-popping vista. The peaks around SLO offer hiking and biking, guided or not. Some dozen wineries in the valley have tastings. A thriving theater scene includes the Cal Poly campus's performing arts center.

Weather

In San Luis Obispo, you can usually expect the usual

Pack those shorts and T-shirts and plan on outdoor activities, even if that morning marine fog makes the day seem iffy. Like much of coastal Southern California, San Luis Obispo has a cool, Mediterranean climate—dry in the summer, with daytimes in the 70s, and slightly wetter and cooler in winter. But be prepared for extremes, such as a scorching, 100-degree-plus stretch anytime from April through October, a 90-degree day in January, or a dip below zero for a day or so between November and February.

Natural features

In a happy spot between L.A. and Monterey

San Luis lies in a broad valley surrounded by peaks—of which the tallest, Bishop Peak, and others are open for hikes that reveal stunning views. A San Luis Obispo vacation rental is a rewarding stopover for coastal travelers midway between L.A. and Monterey. It's only 11 miles from the coast, so the beach is an easy diversion from town sights. Follow the coast north to Morro Bay to view sea otters and herons, try Piedras Blancas for elephant seals, or head south to Pismo Beach between October and February to glimpse migrating butterflies.

How to get there

Traveling to and around San Luis Obispo

Fly into San Luis Obispo, CA (SBP-San Luis Obispo County Regional), the closest airport, located 3 mi (4.9 km) from the city center. If you can't find a flight that's convenient for your trip, you might consider flying into Santa Maria, CA (SMX-Santa Maria Public), which is 28.8 mi (46.4 km) away.

If you prefer train travel, the main station serving the city is San Luis Obispo Station.

How many vacation rentals are available around San Luis Obispo, CA?

Our 2021 property listings offer a large selection of 823 vacation rentals around San Luis Obispo. From 521 house rentals to 48 cabin rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What are the popular point of interests near where I can stay when traveling to San Luis Obispo?

Vrbo offers a large selection of vacation rentals near lovely places in San Luis Obispo. From Vrbo travelers, the top most popular points of interest to stay for a holiday trip or just for a weekend are:

California Polytechnic State University: 900 vacation rentals
Mission San Luis Obispo de Tolosa: 864 vacation rentals
Edna Valley Vineyard: 609 vacation rentals
Bishop Peak Trail: 899 vacation rentals
San Luis Obispo Botanical Garden: 921 vacation rentals

But there are many other points of interest around San Luis Obispo listed on Vrbo where you can find your place to stay. Please use our search bar to access the selection of vacation rentals available near the point of interest of your choice.

Can I rent Houses in San Luis Obispo?

Yes, of course. Vrbo has 521 Houses in San Luis Obispo. Our other popular types of vacation rentals in San Luis Obispo include:

Cabins: 48 rentals available
Cottages: 48 rentals available
Condos/Apartments: 226 rentals available

But you can also enjoy a great stay in one of our other vacation rentals including Bungalows and more.

Can I find a vacation rental with pool in San Luis Obispo?

Yes, you can select your preferred vacation rental with pool among our 70 vacation rentals with pool available in San Luis Obispo. Please use our search bar to access the selection of vacation rentals available.