Discover a selection of 5,000 vacation rentals in La Mesa, CA that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $116 per night, and houses and condos are popular options for a stay in La Mesa. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — La Mesa
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Destination guide

Friendly La Mesa will entice you

Enjoy the entertainment and other features of La Mesa. This welcoming city is known for its bird watching, shopping and restaurants. San Diego Zoo and San Diego Convention Center are just a couple of the must-sees in the area. Many rental homes come with outdoor spaces, separate dining areas and full kitchens, perfect if you want to enjoy some home-cooked meals.

Things to do

Activities and attractions in La Mesa

Do you want to discover attractions to visit while you're in the area? Venture out of your vacation home and experience everything that La Mesa has to offer. These are some of the major attractions to see, all within 30 miles (48.2 km) of the city center:

  • San Diego Zoo (7.8 mi / 12.5 km)
  • Aquatica (12.5 mi / 20.1 km)
  • Belmont Park (13.3 mi / 21.4 km)
  • Birch Aquarium (14.8 mi / 23.9 km)
  • Torrey Pines Golf Course (15.9 mi / 25.7 km)
  • Carlton Oaks Country Club (5.2 mi / 8.4 km)
Natural features

Exploring the natural landscape of La Mesa

Whether you're looking for fun outdoor activities or just want to appreciate the scenery, La Mesa is a great place to get out in nature. These are a few of the area's most eye-catching natural features, all within 30 miles (48.2 km) of the city center:

  • Balboa Park (7.6 mi / 12.2 km)
  • Mission Bay (11.8 mi / 19 km)
  • Mission Beach (13.4 mi / 21.5 km)
  • Mission Trails Regional Park (4.1 mi / 6.6 km)
  • Santee Lakes (5.4 mi / 8.8 km)
  • Waterfront Park (9.2 mi / 14.8 km)
How to get there

How to get to and around La Mesa

The nearest airport is in San Diego Intl. Airport (SAN), located 10.4 mi (16.8 km) from the city center. If you can't find a flight that's convenient for your trip, you could book a flight to San Diego, CA (SEE-Gillespie Field), which is 4.9 mi (7.8 km) away.

You can see more of La Mesa by jumping on the metro at La Mesa Boulevard Station, Spring St Trolley Station or 70th St. Trolley Station.

What are the top vacation rentals in or near La Mesa?

The heart wants what it wants, and right now it's craving a vacation. Now's the time to pack your suitcase and zip off to one of these top vacation rentals in or near La Mesa:

  • Around 7 miles from the center of La Mesa, it's hard to beat "Balboa Park Super Luxe Tropical Hideaway Minutes To The Zoo". It has 2 bedrooms and a host of amenities including a nearby beach and a washing machine.
  • Alternatively, unpack your suitcase at "Treat Yourself Lake Views - Serenity". Around 25 miles from the heart of La Mesa, it has 2 bedrooms and features a lake view and a firepit.

For even more great options, use the search bar at the top of the page to find the perfect La Mesa vacation rental for you.

What are the best tiny house vacation rentals in or near La Mesa?

For a unique vacation experience, book a tiny house rental in La Mesa. We'll warn you though — after you've experienced the tiny house lifestyle, the urge to move into one of these pint-sized pads will be hard to resist!

  • Take a couple of days off to reenergize at "Travelers Tiny Home Oasis With Private Hot Tub". Located in San Diego, heating and free toiletries are a couple of amenities on offer here.
  • Alternatively, book a weekend away at "Camplux Tiny Home". Located in West Ridge, this little gem comes with air conditioning and cable/satellite TV services.

Can I find log cabins to rent in or near La Mesa?

Select a beautiful log cabin from the many dotted in or around La Mesa and you'll soon be inside your wooden hideaway, wine in hand, sitting next to a crackling fire. But adventure is just outside your front door too. These cabins promise the perfect blend of comfort and fun:

  • "New Coleman Creek, Authentic Log Cabin + Spa In Forest. Thoroughly Disinfected": This is the perfect base to try some of the terrific outdoor activities this area has on offer, including mountain biking and hiking and biking.
  • "Charming Log Cabin Surrounded By The Hills Of The Cleveland National Forest": Stay in and enjoy the quiet atmosphere or get out and try some fun activities nearby, including cycling and hiking and biking. You can be as chill or active as you like.

What are the top-rated vacation rentals for weekend getaways in or near La Mesa?

Put aside those household chores, because weekends were made for having fun. Make your way to one of these weekend getaways in and around La Mesa and experience all the exciting things to do close by:

  • "Kennebeck Ct, 30 Seconds To Sand" is a comfortable option around 15 miles west of central La Mesa. You'll never need to venture far to find an unforgettable experience around here. Get outdoors and discover Solana Beach and Centro Cultural de la Raza. Activities like kayaking and windsurfing will add the perfect finishing touch to your short break.
  • Alternatively, leave your troubles behind at "You've Just Found San Diego's Most Unique Family Gathering Place". Use it as a base to relax, or be adventurous and try fishing and mountain biking. When it's time to explore more of the area, plan a visit to Carlton Oaks Country Club and New Americans Museum. This sought-after vacation rental is around 7 miles southeast of La Mesa.

Can I find studio apartments for rent in and around La Mesa?

Usually small in size, less expensive and conveniently located, it's hard not to be charmed by a studio apartment. Escape to one of these options and experience the energy of La Mesa up close:

  • Throw your bags down at "Treetop Luxury Suite At Tropical Resort". Amenities including a microwave oven and a nearby zoo will help you feel at home here.
  • Alternatively, slip into vacation mode at "50' From Ocean - Amazing View - Private Cottage", which comes with conveniences including a nearby zoo and a nearby bay.

With the cash you save on your studio apartment, you can afford to see more of La Mesa. Cultural sights like Museum of Photographic Sciences and Red Spade Theater will help you better understand the character of this destination.

Can I find short term rentals in or near La Mesa?

Just because you only have a couple of days free doesn't mean you have to spend it in a bleak hotel room. Take a quick vacation but still have the comforts of home at one of these short-term rentals in or around La Mesa:

  • "Fort 1 Craftsman On The Woods - Quiet" is close to the heart of La Mesa, which means you'll have loads of things to do and see. Check out well-known attractions like San Diego Zoo and San Diego Convention Center when you're not chilling in your cozy property.
  • Eat, sleep and explore what's around you from "Right On The Beach Exquisitely Remodeled 3br", another exceptional option. Balboa Park and University of San Diego should be on your must-do list when it's time to sightsee.

What are the best romantic weekend getaways in or near La Mesa?

Nothing says "I love you" like a romantic weekend together. If you want to spend a couple of nights away with your sweetie, we've got some romantic getaways in and around La Mesa that will get your heart racing:

  • Around 7 miles from La Mesa, "Balboa Park Super Luxe Tropical Hideaway Minutes To The Zoo" is the ideal place for starry-eyed lovebirds. A fireplace and daily housekeeping services are among the many amenities here.
  • Another place where you can enjoy a few magical days together is "Treat Yourself Lake Views - Serenity". Located 25 miles from La Mesa, winery tours and a firepit add to the atmosphere here.

Are there mansions for rent in or near La Mesa?

We've got some awesome mansions for rent in and near La Mesa. If you're searching for somewhere with lots of space as well as a large dose of wow factor, these stunners will tick your boxes:

  • Located about 9 miles to the west of La Mesa, "New Stunning Mansion Amazing Location" is the perfect place to relax and unwind in luxury. Amenities here include beauty services and golf.
  • With golf, beauty services and a host of other awesome amenities, "San Diego's Tuscan Villa Mansion On The Beach" will dazzle you and your guests. This plush retreat is roughly 15 miles to the west of La Mesa.

What are the best large group vacation rentals in or near La Mesa?

Vacation with others and have twice as much fun. Whether you're organizing an action-packed escape with friends or a family reunion, there's no shortage of large group vacation rentals in and around La Mesa:

  • Offering space, privacy and comfort, you'll get your guests' nod of approval at "You've Just Found San Diego's Most Unique Family Gathering Place". Up to 14 people can stay at this property which has 5 bedrooms, a fireplace and a swimming pool. This group favorite is around 7 miles to the southeast of La Mesa.
  • Nothing takes priority over hanging out with the people you love, and "Perfect For 2 Or 3 Families. Unobstructed Park And Ocean Views. Steps To Sand" makes it easy to do that. Located around 16 miles to the northwest of La Mesa, as many as 15 people can stay in this vacation rental which has 5 bedrooms. A fireplace and a beach view are among the many amenities on offer here.

What are the best houses for rent with a pool in or near La Mesa?

Nothing says fun and frivolity like a pool does. Pump up your inflatable unicorn and browse these rental houses in or near La Mesa that feature this must-have amenity:

  • Round up your gang and enjoy an unforgettable break at "Luxury Lake House And Treehouse Daybed 5". There's a lot to love about this getaway besides its pool, such as a nearby laundromat and a balcony.
  • Otherwise, enjoy a change of scenery at "Read Our Reviews Guests This Family Friendly House". In addition to its inviting pool, make use of nearby birdwatching activities and on-site watersports.

Not sure what the weather is like in La Mesa? It has a semi-arid climate, with average summertime temperatures ranging from 65 ºF to 80 ºF. If you're seeking more inspiration on where to stay in this epic destination, use the search bar at the top of the page and adjust the filters to look through our entire selection of La Mesa vacation rentals.