Mission Bay, San Francisco Vacation Rentals: house rentals & more

Discover a selection of 106 vacation rentals in Mission Bay, San Francisco that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $186 per night, and houses and condos are popular options for a stay in Mission Bay. Either way, you'll find a rental for everyone's needs.

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Stayed Sep 2021

Perfect Location

Perfect location to walk anywhere you’d want to go in the city and easy access to transit if you aren’t up for walking. Great coffee shop two minutes around the corner. The space is just as the photos show, with a comfy bed and nice outdoor space alo...

Stayed Aug 2021

Gem of a property in Dogpatch

We really enjoyed our stay at this great Victorian property. It was close to the T line on the MUNI so it was very easy to get around San Francisco. There were also some nice restaurants close by and quite a few locations that you could pick up any s...

Stayed Jul 2021

Review of SoMa apartment

Great place to stay, however there were a lot of flies in the apartment from the beginning. Other than that, everything was great and I really appreciated Diego's responsiveness to my requests and thought the apartment was great, in a good location w...

Stayed Feb 2021

A-1 homestay

Everything about this home is very beautiful. The pictures are nice, yet in person it makes you double take lol. The owners Karie & Jeff was nothing short of AMAZING!!! I was here at the home almost 2 months and anything I needed (which was not much)...

Stayed Dec 2020

Great Clean & Modern Studio in South Beach

Andrew's property is cozy, clean, and modern in the ideal location, steps away from the Embarcadero and nearby grocery stores, Philz Coffee, and restaurants. The studio itself has all the amenities you could need, including an in-unit washer and drye...

Stayed Sep 2020

Potrero Hill Bohemian

This flat is every bit as sunny and spacious as the pictures show. Because of COVID, I wasn't able to use the kitchen to entertain, as I did a couple of times last year. The furnishings are eclectic and the overall look and feel of the place is enjoy...

Stayed Jul 2020

Center of It All!

Beautiful property and perfectly located close to the Embarcadero for sun-filled runs and outdoor dining. Walking distance to grocery and department stores. Very quite, which was nice during the hours when I actually needed to work from "home." Traff...

Stayed Jan 2020

SOMA Stay

We were really pleased with this apartment. The place is super clean and very comfortable. The kitchen was perfect for making breakfast every morning (we had dinner out). We were able to walk to Moscone Center everyday for our trade show. There is co...

Find the best place to stay — Mission Bay

Search 106 vacation rentals

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How many vacation rentals are available around Mission Bay, San Francisco?

Our 2021 property listings offer a large selection of 106 vacation rentals around Mission Bay. From 7 house rentals to 99 condo and apartment rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What are the popular point of interests near where I can stay when traveling to Mission Bay?

Vrbo offers a large selection of vacation rentals near lovely places in Mission Bay. From Vrbo travelers, the top most popular points of interest to stay for a holiday trip or just for a weekend are:

UCSF Mission Bay: 2,319 vacation rentals
UCSF/Chase Center Stop: 2,318 vacation rentals
UCSF Mission Bay Stop: 2,321 vacation rentals
Mission Rock Station: 2,278 vacation rentals
UCSF Medical Center Station: 2,315 vacation rentals

But there are many other points of interest around Mission Bay listed on Vrbo where you can find your place to stay. Please use our search bar to access the selection of vacation rentals available near the point of interest of your choice.

Can I rent Houses in Mission Bay?

Yes, of course. Vrbo has 7 Houses in Mission Bay. Our other popular types of vacation rentals in Mission Bay include:

Condos/Apartments: 99 rentals available
Studios: 89 rentals available
House: 7 rentals available

Can I find a vacation rental with pool in Mission Bay?

Yes, you can select your preferred vacation rental with pool among our 35 vacation rentals with pool available in Mission Bay. Please use our search bar to access the selection of vacation rentals available.