Discover a selection of 500 vacation rentals in Downtown San Francisco that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including parking and WiFi. Prices start at $70 per night, and condos and houses are popular options for a stay in Downtown San Francisco. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — Downtown San Francisco
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Destination guide

The exciting city of Downtown San Francisco awaits you

Take a vacation to Downtown San Francisco and enjoy the area's architecture, museums and art galleries. Well-liked for its shopping, theaters and entertainment, this city is both cosmopolitan and walkable. San Francisco Museum of Modern Art, Asian Art Museum of San Francisco and Louise Davies Symphony Hall are a few of the top cultural sights. Many of our vacation rentals offer full kitchens, spacious living quarters and sometimes even a hot tub—perfect for a relaxing getaway.

Activities

Activities and attractions in and around Downtown San Francisco

Do you want to discover attractions to visit in the city? Although it can be tempting to stay in your comfortable vacation rental, you'll want to check out everything that makes Downtown San Francisco a fun spot to vacation. Here are some of the most popular attractions to put on your list, all within 30 miles (48.2 km) of the city center:

  • Pier 39 (1.9 mi / 3 km)
  • Aquarium of the Bay (1.8 mi / 3 km)
  • San Francisco Zoo (6.7 mi / 10.7 km)
  • Yerba Buena Ice Skating Center (0.1 mi / 0.1 km)
  • San Francisco Zen Center (1.5 mi / 2.5 km)
  • Powell and Market Cable Car Turnaround (1.8 mi / 2.8 km)
Natural features

Exploring the natural features in Downtown San Francisco

Whether you're looking for exciting outdoor activities or just want to take in the scenery, Downtown San Francisco is a great place to spend some time outside. Here are a few of the area's most eye-catching features, all within 30 miles (48.2 km) of the city center:

  • Palace of Fine Arts (3.1 mi / 5 km)
  • Twin Peaks (3.4 mi / 5.5 km)
  • Japanese Tea Garden (3.9 mi / 6.2 km)
  • Golden Gate Park (4.4 mi / 7 km)
  • Angel Island (6.2 mi / 10 km)
  • University of California Botanical Garden at Berkeley (10.9 mi / 17.5 km)
How to get there

Traveling to and around Downtown San Francisco

The nearest airport is in Oakland, CA (OAK-Oakland Intl.), located 11.3 mi (18.2 km) from the city center. If you can't find a flight that's convenient for your trip, you might consider flying into San Francisco, CA (SFO-San Francisco Intl.), which is 11.5 mi (18.6 km) away.

If you prefer train travel, the main station is San Francisco 4th and King Station. You can see more of Downtown San Francisco by jumping on the metro at Powell St. Station, Montgomery St. Station or Embarcadero Station.

How many vacation rentals are available around Downtown San Francisco?

Our 2021 property listings offer a large selection of 584 vacation rentals around Downtown San Francisco. From 435 condo and apartment rentals to 97 house rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.