Discover a selection of 2,000 vacation rentals in South San Diego, US that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and private pools. Prices start at $120 per night, and houses and condos are popular options for a stay in South San Diego. Either way, you'll find a rental for everyone's needs.
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How many vacation rentals are available around South San Diego, US?

Our 2021 property listings offer a large selection of 1,868 vacation rentals around South San Diego. From 705 house rentals to 861 condo and apartment rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.