Discover a selection of 1,000 vacation rentals in Duck Key that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and private pools. Prices start at $198 per night, and houses and villas are popular options for a stay in Duck Key. Either way, you'll find a rental for everyone's needs.
Top rated rentals — Duck Key
Destination guide

Duck Key gives travelers a fun, tropical trip

Located on a small island in the middle of the Florida Keys, Duck Key is an unincorporated community in Monroe County. Once known for its history with salt production, the island is now known for its charming inns, Caribbean-style cottages, and recreational facilities. Fishing, scuba diving, and other water-based activities are popular activities travelers at Duck Key vacation rentals often enjoy while staying here. The community is also close to many equally appealing towns, although it offers a less bustling and more serene setting.

Things to do

Duck Key attractions travelers will want to see

A list of Duck Key things to see will definitely include the Crane Point Museums and Nature Center and its accompanying natural history museum, bird rescue center, and nature trails and the Keys History & Discovery Center in nearby Islamorada. A ferry provides convenient transportation for travelers at Duck Key vacation rentals wishing to explore areas between Key West and Fort Myers and the mainland. It's within these perimeters where you can find bars and clubs near Sunset Pier, the family-friendly Dry Tortugas National Park—home to 7 islands, a protected coral reef, and an assortment of beaches—and the Key West Butterfly and Nature Conservatory.


Things to add to your Duck Key to-do list

If you're coming to Duck Key to do anything involving the water, you won't be disappointed. Options include wave running, swimming, snorkeling, water skiing, and fishing. Local beaches and nearby state parks are perfect spots for enjoying sunsets, walking, biking, and even shark-watching from a safe distance. Travelers to Duck Key vacation rentals can fill up their shopping bags at area boutiques or sign up for a private or guided tour of adjacent islands. The Overseas Highway makes it easy to plan day excursions throughout the region.


Find tropical weather in Duck Key

The climate in Duck Key is considered tropical wet-and-dry, characterized by annual rainfall of about 30 inches per year and more than 200 days of sunshine per year. Adjacent waterways keep humidity levels tolerable most of the time, which is why the comfort index for the area is above the national average. While frost may occasionally settle on the mainland, the coldest temperature ever recorded here was a still-comfy 41 degrees. Duck Key average temperatures in the summer are in the 80s and in the 60s during the winter months, and the air quality here is nearly 20 percent better than the national average.

Natural features

Explore Duck Key's geographic and natural features

Duck Key is on the oceanside of the Overseas Highway between Conch and Grassy Keys. The community is bordered by waters that aren't far from the Florida Reef, the third-largest barrier reef system in the world. Natural features of the area also include inland wetlands and natural habitats. Nearly 500 native species call the region home. And it's not difficult to find a Duck Key beach near adjacent waterways with dolphins and schools of fish off in the distance.

How to get there

Traveling to and around Duck Key

The nearest airport is in Marathon, FL (MTH-Florida Keys Marathon), located 9.1 mi (14.7 km) from the city center. If you can't find a flight that works for your travel itinerary, you could also fly into Key West, FL (EYW-Key West Intl.), which is 54.8 mi (88.2 km) away.

How many vacation rentals are available around Duck Key?

Our 2021 property listings offer a large selection of 891 vacation rentals around Duck Key. From 709 house rentals to 41 villa rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.