Discover a selection of 79 vacation rentals in Melrose, FL that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and private pools. Prices start at $126 per night, and houses and condos are popular options for a stay in Melrose. Either way, you'll find a rental for everyone's needs.
Top rated rentals — Melrose
Destination guide

Book a vacation rental for your Melrose getaway

Learn about the unique charm of Melrose with a stay in a private vacation home. You'll find plenty to explore during your stay in the area. Many rental homes come with outdoor spaces, separate dining areas and full kitchens, perfect if you want to enjoy some home-cooked meals.

Things to do

Activities and attractions in and around Melrose

Are you searching for things to do while you're in the area? Venture out of your cozy vacation rental and check out everything that makes Melrose a fun place to get away. Here are some of the major attractions to put on your list, all within 30 miles (48.2 km) of the city center:

  • Waldo Motorsports (10.2 mi / 16.3 km)
  • Royal Manor Winery (13.2 mi / 21.2 km)
  • Ironwood Golf Course (14.9 mi / 24 km)
  • Starke Golf and Country Club (16.2 mi / 26 km)
Natural features

Exploring the natural landscape of Melrose

Whether you're an adventurous traveler or just want to appreciate the scenery, Melrose is a great place to spend some time outside. Here are a few of the area's noteworthy natural features, all within 30 miles (48.2 km) of the city center:

  • Kingsley Lake (18.1 mi / 29.1 km)
  • Paynes Prairie Preserve State Park (19.9 mi / 32 km)
  • Santa Fe Lake (2.9 mi / 4.6 km)
  • Mike Roess Gold Head Branch State Park (10.6 mi / 17.1 km)
  • Gold Head Branch State Park (11 mi / 17.7 km)
  • Lake Blossom Hiking Trailhead (13.2 mi / 21.2 km)
How to get there

Traveling to and around Melrose

The nearest airport is in Gainesville Regional Airport (GNV), located 13.7 mi (22.1 km) from the city center.

What are the top vacation rentals in or near Melrose?

Whatever you're looking for in a getaway, you'll find a rental in or around Melrose that's right up your alley. Here are some of our faves:

  • "Hawthorne - Blue Lake Cottage - Lakefront" is popular with guests. Around 14 miles from Melrose, it has 1 bedroom and plenty of useful amenities, including a boat and an ice maker.
  • "Distinctive Overwater Bungalow 360 Degree Water Views" is another top pick, offering 2 bedrooms, free toiletries, tennis and more. It's around 35 miles from Melrose.

For even more great options, use the search bar at the top of the page to find the perfect Melrose vacation rental for you.

What are the top-rated vacation rentals for weekend getaways in or near Melrose?

Escape the rat race at one of our weekend getaways in or near Melrose. Whether you'd like to hang out with buddies or spend quality time with your love, we'll have something to suit your style. Try these top-rated properties on for size:

  • "St Johns River Front Home Huge Deck" is around 25 miles east of Melrose and the perfect place to recharge your batteries. You'll appreciate the range of amenities here, including a garden and a kitchen.
  • Otherwise, make memories with your gang at "5 Star Lake Front On Melrose Bay Gorgeous Lake Santa Fe Property", which is around 1 mile to the north of Melrose. Take advantage of off-street parking options, a washing machine and more here.

Can I find studio apartments for rent in and around Melrose?

Studio apartments are a simple yet stylish choice, perfectly suited for one or two guests. Spend your days getting acquainted with the area and your nights relaxing in your comfy hideaway. These properties in or near Melrose are sure to please:

  • Chill by yourself or take a few pals to "Hawthorne - Blue Lake Cottage - Lakefront". You'll have lots of amenities to make your stay comfortable, including an ice maker and outdoor furniture.
  • "Family Style Covered Wagon Glamping At Animal Sanctuary" is another wonderful stay, providing all you could need for the ideal Melrose adventure. Some amenities here include air conditioning and shopping.

Can I find short term rentals in or near Melrose?

Whether you're after a studio apartment or a house to fit the whole family, you'll find the perfect place on Vrbo. Enjoy some downtime at one of these favorite picks in or near Melrose:

  • Within easy reach of central Melrose, "5 Star Lake Front On Melrose Bay Gorgeous Lake Santa Fe Property" rolls out the welcome mat for short-term guests. When you're not chilling out in your cozy digs, get out and explore the area's best sights.
  • Another great option is "Magnolia Pointe Lakehouse On Lake Santa Fe In Melrose". Round up your crew and enjoy a comfy stay close to the heart of Melrose.

What are the best romantic weekend getaways in or near Melrose?

Nothing says "I love you" quite like planning a romantic weekend together. If you're longing to spend a couple of nights away with your sweetie, we've got some romantic getaways in and around Melrose that will whisk you off your feet:

  • Put on some relaxing music and slow dance the nights away at "Hawthorne - Blue Lake Cottage - Lakefront". Around 14 miles from Melrose, this property has everything you could want for a couple's weekend away, including a firepit and a dining table.
  • "Gainesville Area Lakefront Home - Riley Lake - Canoe Jonboat Kayaks Unlimited Wifi" is another popular option that'll woo you. It's about 13 miles from Melrose and comes with a restaurant dining guide and air conditioning.

What are the best large group vacation rentals in or near Melrose?

Big groups mean big fun. They also mean finding someplace that'll easily fit your crew. Check out our large group vacation rentals in or around Melrose and get your favorite people together under the same roof:

  • You'll have ample space to spread out at "Rent Entire Mansion". Around 25 miles east of Melrose, this expansive property has 7 bedrooms and sleeps up to 20 guests. Quality amenities include a nearby river and a kitchen.
  • "Lakefront Home On 4 Acres - Clear Sandbottom Lake" is another awesome option. It's around 30 miles to the southeast of Melrose, has 4 bedrooms and accommodates up to 12 guests. A kitchen and a fireplace are among the things designed to make your group getaway even more comfortable.

What are the best houses for rent with a pool in or near Melrose?

From games of sharks and minnows to peaceful morning dips, a pool promises fun for both kids and adults. Earn brownie points with friends or family by booking a house with a place to swim in or near Melrose:

  • At the top of our list of cool pool retreats is "Welaka House With Private Dock On St Johns River". Traveling families will feel right at home here, with convenient amenities like books and towels also at hand.
  • "Bring Your Boat To Our River House And Enjoy The Beautiful St Johns River" is another top option. After you've enjoyed a dip with the kids, make the most of other conveniences like childrens activities and a TV.

What are the best large family vacation rentals in or near Melrose?

Nanny and Pop-Pop, Great-Uncle Andre ... You can put them on your guest list when you escape to a large family vacation rental in or near Melrose. Get all the people you love together at one of these spacious escapes:

  • Make your trip a memorable one at "Magnolia Pointe Lakehouse On Lake Santa Fe In Melrose". This escape has 3 bedrooms, has space for 8 guests and features a range of amenities, including a TV and a smart TV. You'll find it around 1 mile north of Melrose.
  • Also check out "Quiet Getaway In Updated Home In Fl State Forest". It's around 13 miles to the east of Melrose, has 3 bedrooms and can accommodate up to 8 guests. Useful amenities here include childrens activities and a porch.

It may be tempting, but don't spend your entire time kicking back indoors. Head out and discover some nearby family-friendly attractions, starting with Single Vision Inc..

Can I find family cabin rentals in or near Melrose?

Time spent with family is important, which is why we'll help you find a space where you can truly connect. Rent one of these family cabin rentals in or near Melrose and make memories with the people you love the most:

  • "Rustic Fishing Cabin On Lake Swan" - This sought-after retreat offers clothes washing facilities and internet access and is located approximately 2 miles northeast of the center of Melrose.
  • "Cabin - Beautiful Lake House On Cowpen Lake W" - Another excellent choice, this rental comes with beach sun loungers, outdoor furniture and more. You'll find it around 9 miles to the south of Melrose.

For more options, use the search bar at the top of the page and adjust the filters to find the Melrose vacation rental that's perfect for your needs.

Are there vacation rentals with fire pits in or near Melrose?

Marshmallows, graham crackers, chocolate and a campfire are the four things you need to make a mouthwatering snack and epic vacation memories. If you love the sound of huddling around a fire pit eating s'mores, check out these escapes in or near Melrose:

  • Chat, laugh and sing with your fam around the fire pit at "Hawthorne - Blue Lake Cottage - Lakefront". This getaway comes with lots of other great amenities, such as a garden and a kitchen.
  • Get a blaze going and then enjoy the serene atmosphere at "Gainesville Area Lakefront Home - Riley Lake - Canoe Jonboat Kayaks Unlimited Wifi". This inviting escape also offers a firepit and a nearby waterfront.