Discover a selection of 102 vacation rentals in Grand Isle that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including air conditioning and WiFi. Prices start at $188 per night, and houses and cabins are popular options for a stay in Grand Isle. Either way, you'll find a rental for everyone's needs.
Top rated rentals — Grand Isle
Destination guide

A taste of the Gulf coast in Grand Isle

A long finger of land that pokes out into the Gulf of Mexico from southern Louisiana, Grand Isle is fringed by cotton-white strands of sand on one side and covered in unique wetland habitats on the other. The result is a pretty place where the salt breezes and the swaying grasses combine to make one of the most interesting birding hotspots in the Deep South, and where whitewashed towns of timber-built Grand Isle vacation rentals offer easy access to the boardwalk nature trails and 7-mile stretch of pristine beachfront.

Things to do

Crossing the wetlands and hitting the Gulf in Grand Isle

The winding, weaving courses of the Grand Isle Birding Trail magnetize ornithologists right throughout the year, crossing great tracts of saltmarsh and brackish lagoons where migratory fliers nestle amongst the reeds. Another type of elegant winged creature is on display at the local Butterfly Dome, and it's possible to get the adrenaline pumping on the wetlands with a trip to the Wake Side Cable Park. And talking of getting wet, you can also enjoy sea kayaking and boating outings over to Elmer’s Island and along the shores of the Mexican Gulf.


It's birding and beachcombing galore in Grand Isle

With a 7-mile stretch of picture-perfect beachfront running the whole length of Grand Isle's southern shoreline along the Mexican Gulf, it's hardly a surprise that days of hopping over the sand dunes and combing for shells are what many travelers come in search of. On the other northern shore, you can also find Grand Isle vacation rentals encompassed by the unique Chenier habitats that spread out all over the Mississippi River delta, offering top-notch birding between the pretty forests of beech and oak and American elm.


Fine weather all year round in Grand Isle

With its distinct tropical climate, Grand Isle enjoys hot and humid temperatures all year round. The best time to come is out of the rainy season though, when the winter brings cooler and drier days. That runs from November to March each year, and culminates with the acclaimed Migratory Bird Festival in April. The pleasant weather means Grand Isle is perfect for escaping the cold months of North America, touting its sun-drenched beaches and palm-topped dunes, salt-washed shoreline and sultry winter days.

Natural features

Enjoy the Gulf and the Mississippi delta in Grand Isle

If you book a Grand Isle vacation rentals close to the long and white-sand beaches of the island's southern shore, then you can look forward to front-row seats over the rollers of the Mexican Gulf. Nearby, walls of undulating dunes rise and fall like waves, sea grasses sway on their tops, and palm trees lean into the wind. Meanwhile, the northern side of the island is taken over by wetlands and salt-water marshes, which is what imbues the place with its world-class birding habitats. It's there you'll find the famous Grand Isle Birding Trail to wander and spot rare migratory fliers.

How to get there

How to get to and around Grand Isle

Fly into New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.), the closest airport, located 54.3 mi (87.4 km) from the city center.

How many vacation rentals are available around Grand Isle?

Our 2021 property listings offer a large selection of 102 vacation rentals around Grand Isle. From 91 house rentals to 7 cabin rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.