Discover a selection of 191 vacation rentals in Rochester that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including WiFi and kitchens. Prices start at $63 per night, and houses and condos are popular options for a stay in Rochester. Either way, you'll find a rental for everyone's needs.
Destination guide

Rochester: Home of the Mayo Clinic

It was way back in the late 1800s that the Mayo clan decided to establish their world-famous clinic in the small Minnesotan town of Rochester. In the decades since, that institution has grown to become one of the largest not-for-profit medical ventures on the planet, now drawing millions of visitors to this otherwise sleepy corner of the Midwest for treatment, medical research trials, and high-skilled jobs. Throw in a couple of top-notch craft breweries, and the wonderful rolling forests, lakes, and plains that spread away south out of Minneapolis, and it's easy to see why charming Rochester vacation rentals would be in high demand.

Things to do

Hospitals and heritage homes in Rochester

Of course, a glimpse at the groundbreaking Plummer Building and the other complexes of the original Mayo Clinic is a must for visitors to Rochester. This is the most defining landmark in the city, and tells the tale of the foundation's growth into a global not-for-profit. Also in the downtown district is the acclaimed Heritage House Victorian Museum, which chronicles the life and times of 18th-century Midwesterners with its antique-heavy rooms and distinct period furnishings. Mayowood Mansion is worth a stopover too, as the former home of Charles Mayo and for its spot on the National Register of Historic Places.


Parks and Minnesotan history in Rochester

There's no question that the home of the famous Mayo Clinic has plenty more up its sleeve than just hospital rooms and research laboratories. Visitors here can also spend time wandering charming nature preserves or unraveling fascinating tales of gold rush history from the 19th century. Others will look for Rochester vacation rentals close to Silver Lake, where golf courses, picnic spots, and quaint wedding venues all dot the green lands.


Choose summer over snow in Rochester

Rochester draws visitors all year round with its famous Mayo Clinic, but there's never a better time to drop into the town's sleepy streets than midsummer, sometime between late June and August. That's when the parks, creeks, golf courses, and meadows are all at their most beautiful, and when you'll be best set for seeking out the wildlife of Cascade Creek and the Carley State Park. It's all the top time for paying your respects at the Wall of Remembrance in the local Veteran's Memorial.

Natural features

Rochester is a city of parks and creeks

The Rochester metro area contains a total of 100 designated recreational spots, each with its own creeks, picnic spots, playgrounds, and jogging tracks. However, for a taste of the real Minnesotan wilds, you'll need to go further afield. You could pack up the camping gear and break away to the Oxbow Park in the west, or head east to the wilder Carley State Park, where white pines and orange-breasted orioles lurk over the hiking paths.

How to get there

How to get to and around Rochester

Fly into Rochester, MN (RST-Rochester Intl.), the closest airport, located 7.8 mi (12.5 km) from the city center.

How many vacation rentals are available around Rochester?

Our 2020 property listings offer a large selection of 191 vacation rentals around Rochester. From 116 house rentals to 31 condo and apartment rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

Can I rent a city-center property in Rochester?

Roll out of bed and stroll to the major tourist attractions. Or simply jump straight into the thrilling energy of the big city! Spend your next trip living like a local just steps from all the action, with a city centre vacation rental. Vrbo has 26 centrally located getaway rentals available. Open to more suggestions? Vrbo has tons of other rental options to have a look at, including:

  • 7 riverside vacation rentals.
  • 6 town vacation rentals.
  • 5 rural vacation rentals.

Can I rent a house in Rochester?

If you want an authentic vacation experience and love having lots of room to move, renting a whole house is the way to go. There are 122 options currently listed on Vrbo. Prices start from $30 a night. Or perhaps you'd rather choose one of the area's other popular property types, like:

  • Apartment: 32 vacation homes. Prices start from $40 per night.
  • Hotel: 31 vacation homes. Prices start from $47 per night.
  • Studio: 2 vacation homes. Prices start from $99 per night.

Can I stay in Rochester in a large group?

There's nothing quite like reconnecting with old friends or spending time with your family in a wonderful new location. And what's best, Vrbo has places big enough for everyone. House vacation homes are the favorite option for large groups, with 29 available here. Rental accommodations in the area that are suitable for large groups include:

  • If yours is a group of 6, we offer 44 vacation homes appropriate for that size. Stay a night for as little as $79.
  • Looking for a rental property for 8 guests? We have 31 that will be ideal. You can get one for as little as $76 a night.
  • Hunting down properties for rent to suit 5 guests? You'll be happy to discover we have 21 that'll be ideal. You can get one for as little as $41 per night.

So don't fear! When you travel with us you can take your uncle, your sister and all your mates to Rochester.

Where are the cheapest rentals in Rochester?

Say au revoir to boring cookie-cutter chain-hotel rooms! Delight in the flexibility of staying like a local in a great value rental instead. Feast your eyes on the incredible options available to book on Vrbo. John Adams has bargain written all over it. And with 7 Vrbo rentals at an average price of $67 a night, it isn't hard to see why. Northrup is another good option. We have 41 rentals here, and the average price is around $113 per night.