Discover a selection of 70 vacation rentals in Picayune, MS that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and private pools. Prices start at $72 per night, and houses and condos are popular options for a stay in Picayune. Either way, you'll find a rental for everyone's needs.
Top rated rentals — Picayune
Destination guide

Delight in the natural landscape of Picayune

Learn about the unique charm of Picayune with a stay in a private vacation home. This relaxing city allures visitors with its coffeehouses and golfing. Whether you're planning a family vacation, friends trip or romantic retreat, Vrbo has a great selection of vacation homes. Many rentals come with a full kitchen and separate dining area, perfect if you need a space for entertaining.


Activities and attractions in Picayune

Are you hoping to discover attractions to visit in the city? Venture out of your cozy vacation rental and experience everything that makes Picayune a fun place to get away. These are some of the most popular attractions to explore, all within 30 miles (48.2 km) of the city center:

  • Millbrook Country Club (3 mi / 4.9 km)
  • Infinity Science Center (15.1 mi / 24.3 km)
  • Diamondhead Country Club (18.6 mi / 29.9 km)
  • Oak Harbor Golf Club (22.3 mi / 35.9 km)
  • Bogalusa Country Club (22.3 mi / 35.9 km)
  • Buccaneer Bay Waterpark (22.7 mi / 36.5 km)
Natural features

Exploring the natural features in Picayune

Whether you're an active traveler or just want to take in the scenery, Picayune is a great place to spend some time outside. Here are a few of the area's most eye-catching natural features, all within 30 miles (48.2 km) of the city center:

  • Crosby Aboretum (2.9 mi / 4.7 km)
  • Honey Island Swamp (22 mi / 35.4 km)
  • Buccaneer State Park (22.7 mi / 36.6 km)
How to get there

Traveling to and around Picayune

Fly into Gulfport, MS (GPT-Gulfport - Biloxi Intl.), the closest airport, located 33.9 mi (54.6 km) from the city center.

If you prefer train travel, the main station is Picayune Station.

How many vacation rentals are available around Picayune, MS?

Our 2021 property listings offer a large selection of 70 vacation rentals around Picayune. From 59 house rentals to 10 condo and apartment rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

Can I rent Houses in Picayune?

Yes, of course. Vrbo has 59 Houses in Picayune. Our other popular types of vacation rentals in Picayune include:

  • Condos/Apartments: 10 rentals available
  • Cabins: 3 rentals available
  • Cottages: 3 rentals available

But you can also enjoy a great stay in one of our other vacation rentals including Bungalows and more.

Can I find a vacation rental with pool in Picayune?

Yes, you can select your preferred vacation rental with pool among our 25 vacation rentals with pool available in Picayune. Please use our search bar to access the selection of vacation rentals available.