Discover a selection of 492 vacation rentals in Clayton that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $61 per night, and condos and houses are popular options for a stay in Clayton. Either way, you'll find a rental for everyone's needs.
Destination guide

The friendly city of Clayton awaits you

Enjoy the museums and other features of Clayton. This welcoming city is known for its restaurants, shopping and zoo. Busch Stadium and Gateway Arch are just a couple of the must-sees in the area. Many of our vacation rentals offer full kitchens, spacious living quarters and sometimes even a hot tub—perfect for a relaxing getaway.


Activities and attractions in Clayton

Are you searching for attractions to visit during your stay? Venture out of your cozy vacation rental and experience everything that makes Clayton a fun spot to vacation. These are some of the most popular attractions to put on your list, all within 30 miles (48.2 km) of the city center:

  • St. Louis Zoo (4.2 mi / 6.8 km)
  • Grants Farm (6.6 mi / 10.6 km)
  • Creve Coeur Golf Club (4 mi / 6.4 km)
  • St. Louis Science Center (5.4 mi / 8.7 km)
  • Myseum (8.1 mi / 13 km)
  • St. Louis Children's Aquarium (9.1 mi / 14.6 km)
Natural features

Exploring the natural features in Clayton

Whether you're an outdoor enthusiast or just want to take in the scenery, Clayton is a great spot to appreciate mother nature. These are some of the area's most eye-catching features, all within 30 miles (48.2 km) of the city center:

  • Missouri Botanical Gardens and Arboretum (6.3 mi / 10.2 km)
  • Blackburn Park (4.3 mi / 6.9 km)
  • Forest Park (4.6 mi / 7.4 km)
  • Pagoda Circle (4.8 mi / 7.7 km)
  • Jewel Box (4.8 mi / 7.7 km)
  • Kirkwood Park (4.9 mi / 7.9 km)
How to get there

Transportation to and around Clayton

Fly into St. Louis, MO (STL-Lambert-St. Louis Intl.), the closest airport, located 7.1 mi (11.4 km) from the city center. If you're unable to find a flight that fits your schedule, you might consider flying into St. Louis, MO (SUS-Spirit of St. Louis), which is 15 mi (24.1 km) away.

Consider catching the metro at Clayton Station or Forsyth Station to more easily navigate the city.

How many vacation rentals are available around Clayton?

Our 2020 property listings offer a large selection of 492 vacation rentals around Clayton. From 322 condo and apartment rentals to 161 house rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What is the best area to stay when traveling to Clayton?

Whether you're traveling with family or friends, here are the areas with the largest selection of vacation rentals for a holiday trip or just for a weekend in Clayton:

  • Central West End: 133 vacation rentals
  • Downtown St. Louis: 348 vacation rentals
  • Soulard: 88 vacation rentals
  • Downtown West: 99 vacation rentals
  • Southwest Garden: 60 vacation rentals

For other neighborhoods, please use our search bar to access the selection of vacation rentals available.

What are the popular point of interests near where I can stay when traveling to Clayton?

Vrbo offers a large selection of vacation rentals near lovely places in Clayton. From Vrbo travelers, the top most popular points of interest to stay for a holiday trip or just for a weekend are:

  • St. Louis Children's Aquarium: 584 vacation rentals
  • Missouri Botanical Gardens and Arboretum: 582 vacation rentals
  • Barnes Jewish Hospital: 582 vacation rentals
  • St. Louis University: 587 vacation rentals
  • Forest Park: 584 vacation rentals

But there are many other points of interest around Clayton listed on Vrbo where you can find your place to stay. Please use our search bar to access the selection of vacation rentals available near the point of interest of your choice.

Can I rent Condos/Apartments in Clayton?

Yes, of course. Vrbo has 322 Condos/Apartments in Clayton. Our other popular types of vacation rentals in Clayton include:

  • Houses: 161 rentals available
  • Studios: 294 rentals available
  • Townhouses: 24 rentals available

But you can also enjoy a great stay in one of our other vacation rentals including Cabins and more.

Can I find a vacation rental with pool in Clayton?

Yes, you can select your preferred vacation rental with pool among our 14 vacation rentals with pool available in Clayton. Please use our search bar to access the selection of vacation rentals available.

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