Discover a selection of 500 vacation rentals in St. Louis, MO that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and private pools. Prices start at $75 per night, and houses and cabins are popular options for a stay in St. Louis. Either way, you'll find a rental for everyone's needs.
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Destination guide

St. Louis opens the gate to the West

Step onto the St. Louis side of the Mississippi River and you’ll immediately know you're someplace else. Somewhere big on skies, big on space, and big on promise. Even before the silver arc of the Gateway Arch makes that change real, it's obvious you've said goodbye to the jaded East and hello to the can-do West. Visitors booking St. Louis vacation rentals are here, in part, to be electrified by that change in outlook, but also to revel in city of delightful diversity, top-ranked museums, paddleboat extravaganzas, and melt-in-the-mouth BBQ ribs.

Things to do

Keeping culture playful in St. Louis

St. Louis doesn't do dull when it comes to culture. Step into the City Museum and you'll think you're in an architectural playground. Packed with mazes, chutes, and mind games, it'll flip your idea of what a museum is all about. The Cathedral Basilica of St. Louis blows the mind too, with its stunning series of mosaics. Forest Park keeps your body busy with its tree-lined walks, ice rink, and outdoor boogie fests. Top it all off with a toast to St. Louis' beer scene, which runs from cult craft outfits to the larger local brewers.

Activities

St. Louis—paddles, music, and grills

The Mississippi is what's made St. Louis magnificent. And the view from this mighty river's impossible to beat. So, pile onto a paddleboat to see the glittering Gateway Arch at its river-facing best. Unknown to many, music—from ragtime to blues—has made its mark on this Missouri city. Be sure to check out the clubs of the Delmar Loop to find out more about the musical heritage of the city. And if you're wanting to dip into the city's famed smokehouse heritage, but don't know which St. Louis bar ‘n grill to hit, try a culinary tour led by a local grill gourmet.

Weather

St. Louis—sweetest in fall

This city doesn't just sit on the fault line between the American East and West—St. Louis is also in the middle of a climate conundrum. Here, temperatures see-saw wildly with the passing of the seasons. That makes the shoulder months of spring and fall the best for visitors looking for comfort from their St. Louis vacation rentals. Spring is beautiful, but can be a little unsettled. September and October are especially good for the St. Louis bound, though. It's less showery and visitor numbers dwindle.

Natural features

The wild things in St. Louis

With not one but two mighty rivers running through St. Louis (the Missouri River and the Mississippi River meet here, in case you're wondering), there's no shortage of dramatic natural spectacle here. These 2 rivers form great glittering sweeps that add extra color to the city's sunsets. Wildlife from across the globe can be found in St. Louis Zoo, of course. But the city itself has wild moments of its own, too. Those leaving early from their St. Louis vacation rentals might be lucky enough to spot coyotes, white-tailed deer, or even armadillos ambling the back streets.

How to get there

Transportation options to and around St. Louis

Fly into St. Louis, MO (STL-Lambert-St. Louis Intl.), the closest airport, located 11.7 mi (18.8 km) from the city center. If you're unable to find a flight that fits your schedule, you might consider flying into St. Louis, MO (SUS-Spirit of St. Louis), which is 23.8 mi (38.4 km) away.

If you'd rather travel by train, the main station is St. Louis Gateway Station. It's easy to get around St. Louis by catching a ride on the metro at 8th and Pine Station, Stadium Station or Convention Center Station.

How many vacation rentals are available around St. Louis, MO?

Our 2021 property listings offer a large selection of 592 vacation rentals around St. Louis. From 220 house rentals to 6 cabin rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What is the best area to stay when traveling to St. Louis?

Whether you're traveling with family or friends, here are the areas with the largest selection of vacation rentals for a holiday trip or just for a weekend in St. Louis:

  • Central West End: 129 vacation rentals
  • Downtown St. Louis: 359 vacation rentals
  • Soulard: 84 vacation rentals
  • Downtown West: 123 vacation rentals
  • Southwest Garden: 58 vacation rentals

For other neighborhoods, please use our search bar to access the selection of vacation rentals available.

What are the popular point of interests near where I can stay when traveling to St. Louis?

Vrbo offers a large selection of vacation rentals near lovely places in St. Louis. From Vrbo travelers, the top most popular points of interest to stay for a holiday trip or just for a weekend are:

  • St. Louis Children's Aquarium: 595 vacation rentals
  • Missouri Botanical Gardens and Arboretum: 592 vacation rentals
  • Barnes Jewish Hospital: 595 vacation rentals
  • St. Louis University: 599 vacation rentals
  • Forest Park: 595 vacation rentals

But there are many other points of interest around St. Louis listed on Vrbo where you can find your place to stay. Please use our search bar to access the selection of vacation rentals available near the point of interest of your choice.

Can I rent Houses in St. Louis?

Yes, of course. Vrbo has 220 Houses in St. Louis. Our other popular types of vacation rentals in St. Louis include:

  • Cabins: 6 rentals available
  • Condos/Apartments: 355 rentals available
  • Townhouses: 23 rentals available

But you can also enjoy a great stay in one of our other vacation rentals including Cottages and more.

Can I find a vacation rental with pool in St. Louis?

Yes, you can select your preferred vacation rental with pool among our 48 vacation rentals with pool available in St. Louis. Please use our search bar to access the selection of vacation rentals available.

    Explore destinations around St. Louis

    Central West End
    129 vacation rentals
    Downtown St. Louis
    359 vacation rentals
    Soulard
    84 vacation rentals
    Downtown West
    123 vacation rentals
    Southwest Garden
    58 vacation rentals
    Tower Grove East
    78 vacation rentals
    Tower Grove South
    73 vacation rentals
    Benton Park
    86 vacation rentals
    DeBaliviere Place
    56 vacation rentals
    Near Southside
    61 vacation rentals
    Shaw
    82 vacation rentals
    Lafayette Square
    71 vacation rentals
    LaSalle Park
    57 vacation rentals
    Lindenwood Park
    20 vacation rentals
    Clifton Heights
    19 vacation rentals
    The Gate
    60 vacation rentals
    Clayton-Tamm
    25 vacation rentals
    Compton Heights
    64 vacation rentals
    Northampton
    29 vacation rentals
    Franz Park
    25 vacation rentals