Discover a selection of 74 vacation rentals in Chillicothe that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $117 per night, and cabins and houses are popular options for a stay in Chillicothe. Either way, you'll find a rental for everyone's needs.
Top rated rentals — Chillicothe
Destination guide

Historic Chillicothe will entice you

Take a vacation to Chillicothe and enjoy the area's churches, history and culture. Travelers to this welcoming city praise the shopping, restaurants and entertainment. If you need more space to accommodate a family vacation or friends trip, rental homes often come with separate dining areas and spacious living rooms.


Activities and attractions in and around Chillicothe

Are you looking for attractions to see during your stay? Although it can be tempting to stay in your comfortable vacation rental, you'll want to check out everything that makes Chillicothe a fun place to get away. Here are some of the top attractions to explore, all within 30 miles (48.2 km) of the city center:

  • Spotted Horse Ranch (18 mi / 29 km)
  • Manchester Hill Winery (18.3 mi / 29.5 km)
  • Happy Trails Horseback Rides (24.2 mi / 39 km)
  • Raintree South Golf Club (24.6 mi / 39.5 km)
  • Splashdown Country (29.4 mi / 47.3 km)
Natural features

Exploring the natural features in Chillicothe

Whether you're looking for adventure or just want to appreciate the scenery, Chillicothe is a great spot to appreciate mother nature. Here are a few of the area's noteworthy natural features, all within 30 miles (48.2 km) of the city center:

  • Yoctangee Park (0.5 mi / 0.9 km)
  • Adena Mansion & Gardens (2.4 mi / 3.9 km)
  • Great Seal State Park (4.7 mi / 7.6 km)
  • Scioto Trail State Park (8.2 mi / 13.2 km)
  • Tar Hollow State Park (13.3 mi / 21.5 km)
  • Lake White State Park (16.5 mi / 26.6 km)
How to get there

Traveling to and around Chillicothe

The nearest airport is in Columbus, OH (CMH-John Glenn Columbus Intl.), located 46.1 mi (74.2 km) from the city center.

How many vacation rentals are available around Chillicothe?

Our 2021 property listings offer a large selection of 74 vacation rentals around Chillicothe. From 52 cabin rentals to 61 house rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.