Discover a selection of 181 vacation rentals in Medford that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $85 per night, and houses and condos are popular options for a stay in Medford. Either way, you'll find a rental for everyone's needs.
Top rated rentals — Medford
Destination guide

In the heart of Rogue Valley

The city of Medford lies in the heart of Rogue Valley in southern Oregon, roughly halfway between San Francisco and Portland. The strapline for the town is 'Medford is pretty cool', and most visitors have to agree. From your Medford vacation rental, you can set off on urban adventures enjoying theater productions, microbreweries and local cuisine in cozy restaurants. Alternatively, just a stone's throw away is the vast wilderness which just begs to be explored by foot, bike or kayak. For something a little gentler, visit one of the vineyards to sip on vintages.

Things to do

Enjoy a Broadway production

If you're going to do just one thing in Medford, make it a visit to the Craterian Theater, a cutting-edge performance center which frequently hosts musicals, dance productions and concerts. If you stay in a Medford vacation rental at the right time, you may even be able to see one of the big Broadway tours that come to town. Alternatively, join the fascinating Haunted Brothels and Opium Dens tour to learn about the town's salacious history. The nearby Applegate Trail Interpretive Center offers a glimpse into the lives of the area's pioneers.


Getting outdoors in Oregon

Some might say that what you can't do in southern Oregon isn't worth doing. The list of outdoor activities is simply staggering. Jump on board whitewater rafts to ride the rapids on the Rogue and Upper Klamath Rivers, mountain bike along the Bear Creek Greenway, hike along the foothills and sections of the Pacific Crest Trail or ski down Mount Ashland – it's all on offer around these parts. Alternatively, set up camp along the river banks and cast your net in to bag a salmon or learn about wine production in the local vineyards. Everything is easily accessible from Medford vacation rentals.


A mild climate year-round

Medford is protected by the surrounding mountain range and enjoys a year-round mild climate with little to no humidity. The distinct seasons offer a variety of activities. During the hot summer months, hiking and biking in the surrounding countryside is at its best. It's relatively dry through the year, so no need to bring your coat. The winters usually bring in blankets of snow and are best spent in one of the excellent restaurants sampling local cuisine, exploring a nearby museum or catching a show at the theater. Grab a Medford vacation rental today.

Natural features

The deepest lake in North America

The nearby Crater Lake National Park is just an hour's drive up the road from your Medford vacation rental. It's said that Native Americans watched the crater form over 7,000 years ago when an eruption caused the volcano to collapse. Fast forward to today and the lake is now the deepest in North America, stretching down over a mile. It's one of the most pure and pristine on earth and draws photographers, artists and scientists from all over the world every year. During the winter, the surrounding cliffs get blanketed in snow making it particularly scenic.

How to get there

Traveling to and around Medford

Fly into Medford, OR (MFR-Rogue Valley Intl.), the closest airport, located 2.9 mi (4.7 km) from the city center.

How many vacation rentals are available around Medford?

Our 2021 property listings offer a large selection of 181 vacation rentals around Medford. From 136 house rentals to 25 condo and apartment rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.