Discover a selection of more than 10,000 vacation rentals in South Carolina, US that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including private pools and swimming pools. Prices start at $69 per night, and houses and cabins are popular options for a stay in South Carolina. Either way, you'll find a rental for everyone's needs.
Top rated rentals — South Carolina

How many vacation rentals are available around South Carolina, US?

Our 2021 property listings offer a large selection of 30,057 vacation rentals around South Carolina. From 13,761 house rentals to 696 cabin rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.