Discover a selection of 1,500 vacation rentals in Isle of Palms, SC that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and private pools. Prices start at $81 per night, and houses and condos are popular options for a stay in Isle of Palms. Either way, you'll find a rental for everyone's needs.
Top rated rentals — Isle of Palms
Destination guide

Experience the Isle of Palms from vacation home rentals

With an Isle of Palms vacation rental, you can have your cake and eat it too. Not only do you get the chilled-out island life, complete with beaches, boating, and some of the best golfing in the state, but you also get all the cultural attractions and events of Charleston right on your doorstep. Just off the South Carolina Coast, Isle of Palms is a classy sort of place, catering to a mixed group of permanent and temporary residents all looking for a slice of the good life out on this deliciously laid-back barrier island.

Things to do

Tourist attractions near Isle of Palms vacation homes

With downtown Charleston just a 17-mile drive away, it's difficult to beat an Isle of Palms vacation rental in the awesome location stakes. From theaters and live music to performing arts festivals, South Carolina's first city is a cultural powerhouse, and attractions range from museums and historic buildings to the stingrays and alligators of the vast South Carolina Aquarium. If Civil War history is your bag, then there are plenty of sites hereabouts. Neighboring Sullivan's Island has Fort Moultrie, while the coastal Fort Sumteris one of the most significant monuments in the area.


Activities near Isle of Palms vacation homes

Beaches like these don't come into your life often, and they're going to be a huge part of your stay in your Isle of Palms vacation rental. Whether you're wanting to laze on the sand, swim in the sea, or play some beach volleyball, these beaches have got you covered—and if you turn up at the right point, you might even catch some live music too. There's a busy marina catering to easy-living boaters, while lots of vacationers are drawn to Isle of Palms for the golf scene. The shopping and dining scene isn't bad either.


Local weather for your stay in Isle of Palms vacation rentals

Isle of Palms isn't the sort of place where you're going to be needing igloos and husky dogs. Even in the middle of winter, temperatures are pretty mild and it doesn't freeze very often, though it can get a bit windy sometimes. Summers in this part of the world are hot, but can also be mighty humid, and you'll need to be prepared to get a bit wet. Thunderstorms are pretty much a daily occurrence, and over 40% of the annual rainfall happens in the summer months. If you like it a bit drier, spring or fall are the most ideal seasons for visiting.

Natural features

There are no barriers to relaxation on this island

Isle of Palms is a barrier island on the coast of South Carolina. It's got the Intracoastal Waterway separating it from the mainland on one side, and the Atlantic Ocean stretching away into infinity on the other. The terrain round here is all about sandy beaches and salt marshes, and sunrises round here are the stuff of legend. And the coastal situation and hospitable habitats draw in more than just the travelers. The island might be a favorite spot with affluent vacation home owners, but the real celebrity residents are the nesting sea turtles.

How to get there

How to get to and around Isle of Palms

Fly into Charleston Intl. Airport (CHS), the closest airport, located 15.9 mi (25.6 km) from the city center.

Good for couples

Couple's fun near Isle of Palms vacation homes

Isle of Palms is perfect for a couple’s retreat. Vacation homes are available near romantic locations like Boone Hall Plantation & Gardens, a scenic plantation with a moss-draped trail and a butterfly exhibit, and Capers Island, a barrier island with opportunities for kayaking and camping. You'll also enjoy Breach Inlet, a picturesque beach with a tranquil atmosphere and strong currents for watersports.

What are the top vacation rentals in or near Isle of Palms?

Whether you're planning your next exciting adventure with friends or a romantic getaway with your darling, one of these top vacation rentals in Isle of Palms is sure to catch your eye:

  • "By Boat Only. . . The Smiley Face House": This Saint-Lary-Soulan Ski Resort retreat offers 2 bedrooms and is highly rated among visitors. Amenities such as a boat and a nearby marina help make your stay an enjoyable one.
  • "Luxury, Elevated Pool, Ocean Views": Settle in at this escape in Charleston and you'll have access to lowered locks, games and more. It has 7 bedrooms to accommodate your friends and family.

For even more great options, use the search bar at the top of the page to find the perfect Isle of Palms vacation rental for you.

What are the best tiny house vacation rentals in or near Isle of Palms?

Punching far above its weight when it comes to charm and innovation, a tiny house vacation rental in Isle of Palms provides a front-row seat to big adventure. Power down all your tech and turn your focus to outdoor fun at one of these compact escapes:

  • Get away from it all and get back to basics at "Cottage/tiny House Living Accommodation In Beaufort For Cost". This retreat in Pigeon Point packs plenty of conveniences into its compact space, such as a living room and a washing machine.
  • "Tiny House Near Santee Cooper Lakes And Cooper River" offers conveniences such as lowered locks and towels. Located in Moncks Corner, you'll be able to live large in this small but nicely designed hideaway.

What are the top-rated vacation rentals for weekend getaways in or near Isle of Palms?

Those chores can wait, because weekends were made for having fun. Take time out at one of these weekend getaways in and around Isle of Palms and enjoy all the wonderful things to do nearby:

  • Located 7 miles to the west of central Isle of Palms, "Studio On Shem Creek With A Deep Water Dock And Views Of Freshwater Lake" is popular among adventurous types and nature lovers. Get out and see nearby outdoor attractions, such as Wragg Square and Tillman Park. Then, take the opportunity to try cycling or sailing.
  • Alternatively, unpack your bags at "Charming Mid 1700s Kitchen House". About 11 miles west of Isle of Palms, fun activities around here include windsurfing and fishing. More into sightseeing? Pencil in a visit to Crowfield Golf Club and Charleston Museum.

Can I find studio apartments for rent in and around Isle of Palms?

Typically small in size, less expensive and conveniently located, it's not difficult to fall for the charms of a studio apartment. Get cozy in one of these options and experience the vibe of Isle of Palms up close:

  • Throw your suitcase down at "Studio On Shem Creek With A Deep Water Dock And Views Of Freshwater Lake". Amenities including a nearby waterfront and WiFi help make guests feel right at home here.
  • Alternatively, get away to "Sunroom With Lagoon Views To Enjoy Nature For Long", which comes with conveniences including a stovetop and free toiletries.

When it's time to step outside your studio apartment and discover the highlights, there's loads to keep you occupied around Isle of Palms. Enjoy cultural attractions? Visit Tunnel Vision Mural and I.P. Stanback Museum & Planetarium.

Can I find short term rentals in or near Isle of Palms?

Whether you're looking for a cozy cabin or a large vacation home, you'll find the ideal place on Vrbo. Sneak in some downtime at one of these favorites in or near Isle of Palms:

  • Within close reach of central Isle of Palms, "Charming Mid 1700s Kitchen House" welcomes short-term guests. When you're not relaxing in your cozy digs, get out and discover everything that's around you.
  • Alternatively, spend a few nights at "Sunroom With Lagoon Views To Enjoy Nature For Long". This centrally located property will feel like your home away from home.

What are the best romantic weekend getaways in or near Isle of Palms?

Nothing says "I love you" quite like a romantic weekend rendezvous. If you'd like to spend a couple of nights away with your honey, we've got some romantic getaways in and around Isle of Palms that will get your heart racing:

  • Located around 11 miles from Isle of Palms, "Mid 1700s Carriage House With Courtyard" is a perfect place for lovestruck couples. Shopping facilities and a nearby marina are just some of the amenities here.
  • Another option where you can spend a few relaxing days together is "Lovely Folly Beach Home Just Steps To The Beach". Located around 16 miles from Isle of Palms, a fireplace and beauty services add to the ambiance here.

Are there mansions for rent in or near Isle of Palms?

You'll find some impressive mansions for rent in and near Isle of Palms. If you're seeking somewhere with plenty of room as well as a large dose of wow factor, these architectural stunners will tick all your boxes:

  • Around 11 miles to the west of Isle of Palms is "Luxurious And Spacious Antebellum Mansion". Along with its magnificent design, you'll also love its top-notch amenities, such as golf and beauty services.
  • Alternatively, take your vacation up a notch and settle into "Private 16 Acre Mansion, Pool Beach". It's located about 25 miles to the southwest of Isle of Palms and offers amenities like concierge services, beauty services and more.

What are the best large group vacation rentals in or near Isle of Palms?

Big groups mean huge fun. They also mean finding a place that'll comfortably fit your entire crew. Check out our large group vacation rentals in or around Isle of Palms and get your favorite people together under one roof:

  • A great range of amenities including a swimming pool and a fireplace make "Luxury, Elevated Pool, Ocean Views" a favorite. This generous getaway has 7 bedrooms and accommodates up to 15 people. From central Isle of Palms, it's around 4 miles away to the southwest.
  • "Ocean's Song" Luxury 5br/6ba Home" is another terrific option. It's around 2 miles to the southwest of Isle of Palms, has 5 bedrooms and sleeps as many as 12 guests. A swimming pool and a fireplace are just a couple of things designed to make your group vacation more comfortable.

What are the best houses for rent with a pool in or near Isle of Palms?

Nothing says fun times like a pool does. Grab your inflatable unicorn and check out these rental houses in or near Isle of Palms that come with this vacation perk:

  • Switch to vacay mode at "Mid 1700s Carriage House With Courtyard", where your highest priority will be hanging out by the pool. Amenities such as a nearby laundromat and coffee and tea making facilities help make this retreat a guest favorite.
  • Otherwise, spend your break at "Charming Mid 1700s Kitchen House". Along with a refreshing pool, make use of a toaster and a barbecue grill.

Wondering what the weather is like in Isle of Palms? It has a humid subtropical climate, with average summertime temperatures ranging from 75 ºF to 85 ºF. If you'd like a little more inspiration on where to stay in this impressive destination, use the search bar at the top of the page and adjust the filters to scroll through our entire range of Isle of Palms vacation rentals.

What are the best large family vacation rentals in or near Isle of Palms?

Every get-together with the family should be a memorable one. Whether you're organizing a fun escape with the kids or a party with relatives, Vrbo's large family vacation rentals in or near Isle of Palms offer a comfy home away from home with enough space for everyone:

  • Sleeping up to 10 guests in 4 bedrooms, "Lovely Folly Beach Home Just Steps To The Beach" is the perfect place for some family time. This popular retreat is 16 miles to the southwest of Isle of Palms and has creature comforts that include a porch and a nearby bay.
  • "Luxury, Elevated Pool, Ocean Views" also offers the space you need to share special moments with loved ones. This property is around 4 miles to the southwest of central Isle of Palms and accommodates 15 guests in its 7 bedrooms. Coffee and tea making facilities and a dishwasher will help keep everyone content and comfortable.

If you're looking for family-friendly attractions in the area, you have plenty of choice. Riverbanks Zoo and Garden, Columbia Canal and Riverfront Park and South Carolina State Fairgrounds promise lots of fun for both adults and kids.

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