Discover a selection of 4,000 vacation rentals in James Island, US that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and kitchens. Prices start at $128 per night, and houses and villas are popular options for a stay in James Island. Either way, you'll find a rental for everyone's needs.
Destination guide

Escape to an urban island

Set in Charleston Harbor, James Island is surrounded by lush marshlands and majestic live oak trees. It's one of Charleston's urban Sea Islands and is dotted with a handful of charismatic neighborhoods. From elegant Riverland Terrace to breezy White Point Estates, you'll find yourself immersed in a tightknit community. While boutique hotels in the French Quarter are a treat, James Island vacation rentals unlock a local experience. From heritage bungalows to luxury cottages, you'll be spoilt for choice. Pack a good book, because relaxing on the porch with a mint julep is a compelling way to pass the time.

Things to do

Gaze up at ancient living oaks

As you enter the upmarket Riverland Terrace neighborhood, you'll pass through the Avenue of Oaks. The boulevard is lined with over 70 magnificent live oak trees that are over a century old. The neighborhood is dotted with beautiful James Island vacation rentals, so why not stay in the heart of Riverland Terrace? For a glimpse of the island's history, don't miss the chance to tour McLeod Plantation. Established in 1851, the heritage site is home to the mighty McLeod Oak, which is thought to be over 600 years old.


Connect with nature in James Island County Park

Popular with both locals and visitors alike, James Island County Park is brimming with outdoor activities. There are miles of forested trails to explore and a handful of freshwater lakes to fish in. There's also a park HQ where you can rent pedal boats, kayaks and bicycles. While sleeping under the stars at the park campground is a unique experience, James Island vacation rentals don't compromise on comfort. If you're craving a street scene, you can always daytrip to Charleston. From elegant antebellum architecture to world-class museums, the city is full of charm – and, of course, plenty of Southern hospitality.


Gear up for the Lowcountry Oyster Festival

A temperate climate means James Island enjoys Southern sunshine for most of the year. In the middle of winter, you could find yourself fishing at James Island County Park or launching a boat in the Ashley River. Crowds peak over from June to August, with families flocking to spend summer vacation on James Island. Charleston also throws a lively summer events calendar, including the famous Spoleto Festival USA held over the Memorial Day weekend. Visit in winter and you'll catch the legendary Lowcountry Oyster Festival. It's the world's largest oyster fest, featuring food, wine, music and 80,000 pounds of oysters.

Natural features

Relive the Civil War at Fort Sumter

Separated from Charleston by the Ashley River, James Island was once dotted with Sea Island cotton plantations. Today it's interspersed with small neighborhoods, historic sites and, of course, ancient live oak trees. While it's just a 10-minute drive from downtown Charleston, you'll feel as if you're worlds away from the lively port city. Just offshore is Fort Sumter, a manmade island formed from 10,000 tons of imported New England granite and 60,000 tons of other rocks. This is where the first shots of the Civil War were fired, back in 1861.

How many vacation rentals are available around James Island, US?

Our 2020 property listings offer a large selection of 4,245 vacation rentals around James Island. From 2,046 house rentals to 609 villa rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What are the most popular destinations to visit in James Island?

There are many lovely places to stay for a holiday trip or just for a weekend in James Island. From Vrbo travelers, the top most popular destinations to visit are:

  • Isle of Palms: 2,277 vacation rentals
  • Folly Beach: 2,970 vacation rentals
  • Downtown Charleston: 774 vacation rentals
  • Seabrook Island: 1,328 vacation rentals
  • West Beach: 659 vacation rentals

And Vrbo offers you the chance to discover many other popular destinations in James Island! Please use our search bar to access the selection of vacation rentals available in other popular destinations.

What are the main cities to discover in James Island?

Whether you're traveling with family or friends, here are the cities with the largest selection of vacation rentals for a holiday trip or just for a weekend in James Island:

  • Isle of Palms: 2,277 rentals
  • Folly Beach: 2,970 rentals
  • Seabrook Island: 1,328 rentals
  • Kiawah Island: 2,113 rentals
  • Edisto Island: 1,680 rentals

For other cities, please use our search bar to access the selection of vacation rentals available.

Near which points of interest can I spend my holidays in James Island?

Vrbo offers a large selection of rentals near lovely places in James Island. From Vrbo travelers, the top most popular points of interest to stay for a holiday trip or just for a weekend are:

  • Folly Beach: 2,970 rentals
  • Folly Beach Fishing Pier: 4,368 rentals
  • Morris Island Lighthouse: 4,373 rentals
  • Front Beach: 3,243 rentals
  • Folly Beach County Park: 4,366 rentals

But there are many other points of interest around James Island listed on Vrbo where you can find your place to stay. Just write your wanted destination in our search bar and have a look at our selection.

Explore destinations around James Island

Isle of Palms
2,277 vacation rentals
Folly Beach
2,970 vacation rentals
Seabrook Island
1,328 vacation rentals
Kiawah Island
2,113 vacation rentals
Edisto Island
1,680 vacation rentals
Mount Pleasant
3,107 vacation rentals
North Charleston
2,617 vacation rentals
Sullivan's Island
3,023 vacation rentals
2,197 vacation rentals
Johns Island
4,170 vacation rentals
1,087 vacation rentals
Wadmalaw Island
4,696 vacation rentals
Moncks Corner
2,884 vacation rentals
280 vacation rentals
170 vacation rentals
179 vacation rentals
64 vacation rentals
Goose Creek
2,168 vacation rentals
1,172 vacation rentals
748 vacation rentals