Discover a selection of 2,500 vacation rentals in Ladys Island, SC that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $65 per night, and houses and condos are popular options for a stay in Ladys Island. Either way, you'll find a rental for everyone's needs.
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Destination guide

Take in the waterfront beauty of Ladys Island

The island views and surrounding scenery provide a peaceful ambiance to your vacation home in Ladys Island. This city's restaurants, boating and shopping draw many visitors. With a vacation rental, you get a home away from home—many rentals offer full kitchens and outdoor grills for some home cooking.

Activities

Sightseeing in and around Ladys Island

Are you hoping to find attractions to visit while you're in town? Venture out of your vacation home and experience everything that makes Ladys Island a fun place to get away. These are some of the top attractions to put on your list, all within 30 miles (48.2 km) of the city center:

  • Port Royal Skateboard Park (5.4 mi / 8.7 km)
  • Sanctuary Golf Club (5.8 mi / 9.4 km)
  • Legends Golf Course at Parris Island (10.3 mi / 16.6 km)
  • Colleton River Plantation Golf Club (14.2 mi / 22.8 km)
  • Country Club of Hilton Head (15.5 mi / 25 km)
  • Palmetto Hall Plantation Club (15.9 mi / 25.5 km)
Natural features

Exploring the natural landscape of Ladys Island

Whether you're an adventurous traveler or just want to appreciate the scenery, you'll be sure to find the perfect setting for your vacation in Ladys Island. These are a few of the area's most eye-catching features, all within 30 miles (48.2 km) of the city center:

  • Henry C. Chambers Waterfront Park (2.9 mi / 4.6 km)
  • Cypress Wetlands (5.9 mi / 9.5 km)
  • The Sands (6.3 mi / 10.1 km)
  • Hunting Island State Park (11.9 mi / 19.2 km)
  • Mitchelville Freedom Park (15.1 mi / 24.2 km)
  • Pinckney Island National Wildlife Refuge (15.8 mi / 25.5 km)
How to get there

How to get to and around Ladys Island

Fly into Hilton Head Island, SC (HHH), the closest airport, located 15.9 mi (25.7 km) from the city center. If you can't find a flight that works for your travel itinerary, you might consider flying into Savannah, GA (SAV-Savannah - Hilton Head Intl.), which is 40.3 mi (64.9 km) away.

How many vacation rentals are available around Ladys Island, SC?

Our 2021 property listings offer a large selection of 2,655 vacation rentals around Ladys Island. From 1,578 house rentals to 939 condo and apartment rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.