Discover a selection of more than 10,000 vacation rentals in South Carolina Lowcountry, US that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $98 per night, and houses and cottages are popular options for a stay in South Carolina Lowcountry. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — South Carolina Lowcountry
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What are the top vacation rentals in South Carolina Lowcountry?

Deluxe villas, unique houseboats and spacious homes — everyone's dream place to stay is different. Whatever your style, you're sure to find something that makes your heart skip a beat among our top vacation rentals in South Carolina Lowcountry:

  • "Brand New Beaufort Cottage, Best Location": If you're after a comfy living space in Ladys Island, this escape won't disappoint. It offers 1 bedroom and great amenities including a dining table and an electric car charging station.
  • "Large Home With Beautiful Private Pool And Spa": Put your suitcase down and your weary feet up at this popular getaway in Beaufort. It comes with 5 bedrooms, a balcony, a water view and more.

For even more great options, use the search bar at the top of the page to find the perfect South Carolina Lowcountry vacation rental for you.

What are the best tiny house vacation rentals in South Carolina Lowcountry?

Punching far above its weight when it comes to character and charm, a tiny house vacation rental in South Carolina Lowcountry puts you on the doorstep of big adventure. Turn off all your gadgets and turn your focus to nature at one of these fun-sized stays:

  • Leave it all behind and escape to "Cottage/tiny House Living Accommodation In Beaufort For Cost". This retreat in Pigeon Point packs plenty of comforts into its small space, such as a fridge and a dining table.
  • "Romantic Shabby Chic Tiny House By The Marsh" offers convenient extras like free toiletries and a garden. Located in Beaufort, you'll be able to live large in this small but well-designed hideaway.

What are the top-rated vacation rentals for weekend getaways in South Carolina Lowcountry?

While big extravagant trips are awesome, there's something undeniably lovely about slipping off for a whirlwind weekend getaway. These properties in South Carolina Lowcountry are perfect for just that:

  • "Castle By The Sea 7br/8ba Luxury Home With Elevator" - Located in North Forest Beach, there's no shortage of fantastic stuff to see and do near this rental. Handy amenities like a microwave oven and a washing machine are the cherry on top!
  • "9 Wisteria Ln - 1 Level Renovated Home" - This is another terrific place where you can relax for two or three days. Take advantage of a pool, games and more during your short but memorable stay at this North Forest Beach property.

Can I find studio apartments for rent in South Carolina Lowcountry?

If you want something with more personality than your run-of-the-mill hotel room, you'll like our studio apartments in South Carolina Lowcountry. Cook up a meal in your kitchenette, scroll through social media on the lounge and feel totally at home. Take a peek at some of our coziest cribs:

  • Sleep, eat, relax with friends ... Do it all from the compact yet comfortable single room space at "Brand New Beaufort Cottage, Best Location". Located in Ladys Island, a stovetop and an iron and ironing board are among its amenities.
  • Alternatively, use "Downtown Beaufort Carriage House" as your base to discover the sights around you. This appealing option is in Beaufort and offers shopping and off-street parking options.

Can I find short term rentals in South Carolina Lowcountry?

South Carolina Lowcountry has short-term rentals that come in all styles and budgets. Take a quick break in a simple cabin, a luxurious lodge or whatever else floats your boat. Here are a couple of options to consider:

  • Base yourself near the center of North Forest Beach and spend your days sightseeing from "Castle By The Sea 7br/8ba Luxury Home With Elevator". Along with its great location, this retreat has everything you need to make your vacation relaxed and carefree.
  • Another popular option is "9 Wisteria Ln - 1 Level Renovated Home" in Beaufort. Whether you're just passing through or making the most of a long weekend, this vacation rental will make you feel at home.

What are the best romantic weekend getaways in South Carolina Lowcountry?

A romantic weekend getaway in South Carolina Lowcountry is sure to reignite your passion. Light some candles, take your sweetie by the hand and get set to let the sparks fly at one of these vacation rentals:

  • You'll feel like a regular Casanova at "Brand New Beaufort Cottage, Best Location". This Ladys Island vacation rental is custom-made for romance, offering amenities like a nearby bay and beauty services to help set the mood.
  • Another amorous option is "Large Home With Beautiful Private Pool And Spa" in Beaufort. Enjoy perks here including a swimming pool and shopping facilities, in addition to each other's company.

What are the best large group vacation rentals in South Carolina Lowcountry?

If you're thinking about taking a memorable trip away, don't travel by yourself; bring the whole crew along. You'll have loads more fun sharing your experiences with the people you love. These vacation rentals in South Carolina Lowcountry are ideal for large groups:

  • "Castle By The Sea 7br/8ba Luxury Home With Elevator": Featuring 7 bedrooms, this large vacation rental in North Forest Beach has plenty of room for you and all your besties. Amenities such as a swimming pool and a kitchen will keep everyone happy.
  • "2 Min Walk 2 Beach, Pvt Heated Pool": Located in Beaufort, this knockout has 5 bedrooms and is another popular pick for a get-together with the family. There's a whole lot to keep guests both comfortable and entertained, such as a swimming pool and a fireplace.

Are there large vacation rentals that sleep 30 or more in South Carolina Lowcountry?

If you're planning a huge family get-together or a special event like an anniversary in South Carolina Lowcountry, you won't have to worry about anyone missing out. We've got a range of large vacation rentals that will fit as many people as you want. Here are some great examples:

  • "Selah On The Sound ~ 3 Bedroom Oceanfront On The Sound": With 3 bedrooms sleeping up to 100 people, you'll have ample space at this property in Edisto Beach. Useful amenities here include a nearby beach and off-street parking options.
  • "Large10 Br/11ba Poolelevatorfire Pitbarpalmetto Dunes Resort": Good times are guaranteed at this retreat in Beaufort. It has 10 bedrooms and can accommodate up to 34 guests comfortably. Quality amenities here include a swimming pool and a fireplace.

What are the best houses for rent with a pool in South Carolina Lowcountry?

In South Carolina Lowcountry, you'll find plenty of house rentals where you can make every day a pool day. Having a splashing good time will be your main priority at one of these popular retreats:

  • Book a stay at "Downtown Beaufort Carriage House", where the first thing on your itinerary should be a dip in the pool. This escape is located in Beaufort and features a range of family-friendly amenities, including a dining table and nearby birdwatching activities.
  • Lounge by the water while the kids paddle around at "Private 4br/4. 5ba House With 2 Golf Carts". This option in Beaufort offers a range of conveniences to keep the family comfortable and happy, such as a stair gate and nearby birdwatching activities.

What are the best large family vacation rentals in South Carolina Lowcountry?

Perhaps you're organizing a getaway to celebrate an event, or reuniting with relatives you haven't seen in a while. Whatever the reason, you're going to want extra space. One of our large family vacation rentals in South Carolina Lowcountry could be just the ticket:

  • "Large Home With Beautiful Private Pool And Spa" in Beaufort will make your escape one to remember. It has 5 bedrooms sleeping up to 10 guests and a host of amenities, including a fridge and coffee and tea making facilities.
  • Another top option, "Castle By The Sea 7br/8ba Luxury Home With Elevator" in North Forest Beach offers 7 bedrooms and accommodates up to 18 guests. A kitchen and cable/satellite TV services will keep the whole gang content and comfy.