Discover a selection of 1,000 vacation rentals in Pickens County, US that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including WiFi and swimming pools. Prices start at $89 per night, and cabins and houses are popular options for a stay in Pickens County. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — Pickens County
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How many vacation rentals are available around Pickens County, US?

Our 2022 property listings offer a large selection of 1,176 vacation rentals around Pickens County. From 195 cabin rentals to 902 house rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What are the most popular destinations to visit in Pickens County?

There are many lovely places to stay for a holiday trip or just for a weekend in Pickens County. From Vrbo travelers, the top most popular destinations to visit are:

  • Sunset: 532 vacation rentals
  • Six Mile: 292 vacation rentals
  • Pickens: 60 vacation rentals
  • Rocky Bottom: 232 vacation rentals
  • Clemson: 298 vacation rentals

And Vrbo offers you the chance to discover many other popular destinations in Pickens County! Please use our search bar to access the selection of vacation rentals available in other popular destinations.

What are the main cities to discover in Pickens County?

Whether you're traveling with family or friends, here are the cities with the largest selection of vacation rentals for a holiday trip or just for a weekend in Pickens County:

  • Sunset: 532 rentals
  • Six Mile: 292 rentals
  • Pickens: 60 rentals
  • Clemson: 298 rentals
  • Easley: 198 rentals

For other cities, please use our search bar to access the selection of vacation rentals available.

Near which points of interest can I spend my holidays in Pickens County?

Vrbo offers a large selection of rentals near lovely places in Pickens County. From Vrbo travelers, the top most popular points of interest to stay for a holiday trip or just for a weekend are:

  • Hagood Mill Historic Site: 719 rentals
  • South Carolina Botanical Gardens: 584 rentals
  • Memorial Stadium: 606 rentals
  • Easley Skate Center: 529 rentals
  • Golden Creek Mill: 589 rentals

But there are many other points of interest around Pickens County listed on Vrbo where you can find your place to stay. Just write your wanted destination in our search bar and have a look at our selection.