Discover a selection of 1,500 vacation rentals in Pickens County, US that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including WiFi and swimming pools. Prices start at $86 per night, and cabins and houses are popular options for a stay in Pickens County. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — Pickens County
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Destination guide

Find the perfect vacation rental for your Pickens County getaway

Experience the unique character of Pickens County with a stay in a vacation home rental. This city has something for everyone. Many rental homes come with outdoor spaces, separate dining areas and full kitchens, perfect if you want to enjoy some home-cooked meals.

Things to do

Activities and attractions in and around Pickens County

Are you searching for top things to see and do during your stay? Venture out of your cozy vacation rental and check out everything that makes Pickens County a fun spot to vacation. Here are some of the most popular attractions to see, all within 30 miles (48.2 km) of the city center:

  • Greenville Zoo (18.3 mi / 29.4 km)
  • Frankie's Fun Park (23.7 mi / 38.2 km)
  • Topgolf (25.4 mi / 40.8 km)
  • Moonshine Mountain Snow Tubing Park (29.1 mi / 46.8 km)
  • Old Edwards Club (29.9 mi / 48.2 km)
  • Easley Skate Center (6.8 mi / 10.9 km)
Natural features

Exploring the natural features in Pickens County

Whether you're an outdoor enthusiast or just want to spend some time taking in the scenery, Pickens County is a great place to spend some time outside. These are a few of the area's most stunning sights, all within 30 miles (48.2 km) of the city center:

  • Table Rock State Park (10.5 mi / 16.8 km)
  • Lake Keowee (11.9 mi / 19.2 km)
  • Lake Jocassee (14 mi / 22.5 km)
  • Devils Fork State Park (14.3 mi / 23.1 km)
  • South Carolina Botanical Gardens (16 mi / 25.7 km)
  • Caesars Head State Park (16.7 mi / 26.9 km)
How to get there

How to get to and around Pickens County

If you'd prefer to travel by train, the main station serving the city is Clemson Station.

What are the top vacation rentals in Pickens County?

Whether you're planning your next great adventure with friends or a romantic escape with your special someone, one of these top vacation rentals in Pickens County is sure to entice you:

  • "Cabin - Private Romantic Mountain Getaway": This Pickens property offers 2 bedrooms and is highly rated among visitors. Amenities such as golf and a nearby hospital are on hand to make your stay a comfy one.
  • "Cabin - Peace - In - The - Forest Retreat": Settle in at this property in Easley and take advantage of a free nearby fitness center, WiFi and more. It has 1 bedroom to accommodate your family and friends.

For even more great options, use the search bar at the top of the page to find the perfect Pickens County vacation rental for you.

What are the best tiny house vacation rentals in Pickens County?

For a completely different vacation experience, book a tiny house rental in Pickens County. We'll warn you though — after you've experienced the tiny house lifestyle, the temptation to move into one of thes fun-sized digs will be tough to resist!

  • Experience a simpler way of living at "Cottage/tiny House Living Accommodation In Beaufort For Cost". Amenities at this hideaway in Pigeon Point include a fridge and golf.
  • Alternatively, book a weekend away at "New Boutique Tiny Home On The Saluda River". Situated in Easley, this tiny abode comes with a dryer and a kitchenette.

Can I find log cabins to rent in Pickens County?

Whether you're after a low-key retreat or something luxurious, we've got some great log cabins to rent in Pickens County. Experience adventure and comfort at one of these popular options:

  • If you'd like to be able to enjoy kayaking and fishing while staying in Pickens County, "Log Cabin On Lake Keowee - Big Lake" in Six Mile will be a great fit.
  • Another top choice is "Waterfront Log Cabin On Lake Keowee". With fun activities such as golf and kayaking nearby, this Six Mile retreat will be perfect if you love the outdoors.

What are the top-rated vacation rentals for weekend getaways in Pickens County?

Short on time but eager to get away? A weekend escape will be just what you need. Snap up one of these popular properties and get ready for sleep-ins, good food and relaxation:

  • "Cabin - Hidden Gem - Privacy, Tranquility" - Located in Cleveland, there's plenty of wonderful stuff to see and do near this rental property. Little conveniences like a nearby river and a phone are the cherry on top of the cake!
  • "Book Your Clemson Football Or Fall Get Away Today East Cove Paradise" - This is another top choice offering all the things that make for a special weekend away. You'll have use of a nearby marina and a garden at this Six Mile rental.

Can I find studio apartments for rent in Pickens County?

Studio apartments are often smaller in size, but it's difficult to beat their handy locations and budget price tags. Whether you're traveling alone or with some friends, consider one of these welcoming studio apartments in Pickens County:

  • Get comfy at "Cabin - Peace - In - The - Forest Retreat", located in Easley. There are loads of amenities at your fingertips here, including air conditioning and WiFi.
  • Alternatively, use "A Cabin In The Woods" as your base to discover the sights around you. This homey retreat is in Cleveland and offers water sports equipment and internet services.

Can I find short term rentals in Pickens County?

Pickens County has short-term rentals that come in all sizes, shapes and budgets. Take a quick break in a cozy cabin, an upmarket apartment or whatever else appeals to you. Here are a couple of options to start you off:

  • Located close to central Cleveland, "Cabin - Hidden Gem - Privacy, Tranquility" is perfect for a short-term stay. Set up base here and head out to explore all the interesting sights around the area.
  • Another centrally located option is "Book Your Clemson Football Or Fall Get Away Today East Cove Paradise" in Six Mile. Whether you're on a brief stopover or enjoying a couple of days away, this comfortable vacation rental will make you feel at home.

What are the best romantic weekend getaways in Pickens County?

If you're eager to woo your special someone, then stay somewhere special! Organize a romantic weekend getaway in Pickens County at one of these properties and let love blossom:

  • "Cabin - Private Romantic Mountain Getaway" in Pickens is the perfect setting for romantic interludes. Nice touches here include winery tours and air conditioning.
  • Another amorous option is "Cabin - Peace - In - The - Forest Retreat" in Easley. Enjoy perks here including a fireplace and beauty services, in addition to each other's company.

What are the best large group vacation rentals in Pickens County?

When it comes to planning a vacation, we believe the more the merrier. If you're after a property with enough space to fit your entire crew, one of these large group vacation rentals in Pickens County will satisfy your needs:

  • "Prime Fall Weekends Still Available. Book Today": This popular rental is an excellent choice for larger groups planning to visit Six Mile. It has 5 bedrooms and conveniences that include a fireplace and mountain views.
  • "Evolve | Secluded Cabin With Spacious Interior": Located in Pickens, this spacious option has 6 bedrooms and is another top pick for a fun family break. There's plenty to keep guests comfortable and content, including a kitchen and a fireplace.

What are the best houses for rent with a pool in Pickens County?

Take your pick and dive right in. Here are a couple of exceptional house rentals in Pickens County where life is better by the pool:

  • Book a stay at "New Upscale House With Private Dock On Lake Keowee", where the first thing on your itinerary should be taking a dip in the pool. This getaway is located in Six Mile and features a host of family-friendly amenities, including childrens activities and free toiletries.
  • Read a book by the water while the kids splash around at "Branches Up Tree House Mountain Getaway". This option in Pickens offers a range of conveniences to keep your crew comfortable, such as a balcony and towels.

What are the best large family vacation rentals in Pickens County?

Quality time with family doesn't happen on its own — it takes love, care and an ideal setting. Vrbo can help with the last part. Check out these large family vacation rentals in Pickens County where memories are created and loved ones belong:

  • Located in Six Mile, "Prime Fall Weekends Still Available. Book Today" has 5 bedrooms and fits up to 15 guests. Amenities include a kitchen and nearby birdwatching activities.
  • "Upscale Vacation Home Away From Home" in Pickens will also lay out the welcome mat for you and your team. Accommodating up to 8 people, this retreat features 3 bedrooms, cable/satellite TV services and nearby ecotour services.

If you want to visit some family-friendly attractions in Pickens County, Easley Skate Center is a standout.