Discover a selection of 224 vacation rentals in Greenville, SC that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $54 per night, and houses and cabins are popular options for a stay in Greenville. Either way, you'll find a rental for everyone's needs.
Destination guide

Experience Greenville in vacation home rentals

Set in South Carolina's verdant Upcountry region and surrounded by the leafy forests of the Blue Ridge Mountains, Greenville is aptly named. Its friendly downtown is perfect for a day of shopping, eating, and sipping a craft beer while you watch the leaves change in autumn or the flowers bloom in spring. There are plenty of attractions for kids – zoos, playgrounds, and a waterfall right in downtown. Then again, there's a lot for grown-ups too – art galleries, museums and history tours. You'll be proud you thought to visit this fast-growing city with a cheerful, southern vibe.

Things to do

Attractions near Greenville vacation homes

It's easy to plan a well-rounded day from the comfort of your Greenville vacation rental. For a bit of history, take a look at the Upcountry History Museum, whose exhibits explore South Carolina's 15 upcountry counties from the early 1700s to the present. To nurture your artistic soul, make your way to the Greenville County Museum of Art and its paintings by American and southern artists, including the world's largest public collection of watercolors by Andrew Wyeth. To charm the children, head to the Greenville Zoo, whose habitats host African lions, Masai giraffes and several primate species.


Activities near your Greenville summer rental

It's all happening on Main Street, a 10-block stretch of restaurants, pubs, and cute shops, all within steps of the Reedy River and enchanting Falls Park. Vacationers like to slow down when they get to Greenville. Ride your bike, picnic in the park, or plan a hike in one of the area's stunning state parks. Segway and walking tours are popular with visitors. You can learn about Greenville's checkered past, from the forfeiture of Cherokee land to Jim Crow-era lynchings, or take a break from reality with a light-hearted tour of the settings of Greenville's greatest ghost stories.


Local weather for your trip to Greenville vacation homes

You can book a Greenville vacation rental any time of year and count on good weather. The city is one of those rare spots that boast mild temps year-round even as it marks 4 distinct seasons. The only exceptions are the dog days of summer. Highs can hit the upper 80s and low 90s in July and August, and the humidity is real. Fall brings forest landscapes bursting with color and very little rain. Spring is sunny and warm, not hot. Winter lows rarely fall below freezing.

Natural features

You'll fall for Falls Park and want to pat Caesar's Head

Greenville is tucked among the foothills of the Blue Ridge Mountains, a beautifully lush region of green hillsides, craggy cliffs, and rivers. Reedy River runs through Greenville and is the centerpiece of Falls Park, a 90-acre feast for the senses with a pedestrian suspension bridge and a 60-ft high waterfall. Take a day trip from your Greenville vacation rental to one of the nearby state parks. Caesars Head State Park is named for its striking granite outcropping atop the Blue Ridge Escarpment. It provides breathtaking views and a place to spy hawks swooping overhead.

How to get there

How to get to and around Greenville

Fly into Greenville, SC (GSP-Greenville-Spartanburg Intl.), the closest airport, located 10.7 mi (17.2 km) from the city center.

If you'd prefer to travel by train, the main station is Greenville Station.

Family friendly

Family activities near Greenville vacation homes

Greenville is a prime destination for family fun. Vacation homes can be found near places like Shoeless Joe Jackson Museum, a museum with baseball memorabilia and the former home of the baseball player Joe Jackson, and Otter Creek Waterpark, a seasonal water park with a splash pad, waterslides, and concessions. Kids will also like Discovery Island, an amusement park with waterslides, pools, a lazy river, and simulated surfing.

Good for couples

Romantic vacation homes in Greenville

Couples will have endless options for fun and romance in Greenville. Vacation rentals are close to places like Falls Park on the Reedy, a riverfront park with waterfall views, a suspension bridge, and acres of gardens, and Paris Mountain State Park, a serene park with miles of trails, equipment rentals, and campsites near the lake. You'll also like Lake Conestee Nature Park, a wildlife preserve with paved trails, bog walks, and hundreds of bird species.

How many vacation rentals are available around Greenville, SC?

Our 2021 property listings offer a large selection of 224 vacation rentals around Greenville. From 170 house rentals to 16 cabin rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What is the best area to stay when traveling to Greenville?

Whether you're traveling with family or friends, here are the areas with the largest selection of vacation rentals for a holiday trip or just for a weekend in Greenville:

  • Greenville Downtown: 76 vacation rentals
  • Payne-Logan: 38 vacation rentals
  • Green Avenue: 29 vacation rentals
  • Woodside Cotton Mill Village Historic District: 16 vacation rentals
  • Colonel Elias Earle Historic District: 18 vacation rentals

For other neighborhoods, please use our search bar to access the selection of vacation rentals available.

What are the popular point of interests near where I can stay when traveling to Greenville?

Vrbo offers a large selection of vacation rentals near lovely places in Greenville. From Vrbo travelers, the top most popular points of interest to stay for a holiday trip or just for a weekend are:

  • Heritage Green: 232 vacation rentals
  • Furman University: 275 vacation rentals
  • Gower Estates Park: 222 vacation rentals
  • Bon Secours Wellness Arena: 231 vacation rentals
  • Fluor Field at the West End: 230 vacation rentals

But there are many other points of interest around Greenville listed on Vrbo where you can find your place to stay. Please use our search bar to access the selection of vacation rentals available near the point of interest of your choice.

Can I rent Houses in Greenville?

Yes, of course. Vrbo has 170 Houses in Greenville. Our other popular types of vacation rentals in Greenville include:

  • Cabins: 16 rentals available
  • Condos/Apartments: 40 rentals available
  • Cottages: 16 rentals available

But you can also enjoy a great stay in one of our other vacation rentals including Townhouses and more.

Can I find a vacation rental with pool in Greenville?

Yes, you can select your preferred vacation rental with pool among our 12 vacation rentals with pool available in Greenville. Please use our search bar to access the selection of vacation rentals available.