Discover a selection of 500 vacation rentals in Seneca, SC that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $39 per night, and hotels and houses are popular options for a stay in Seneca. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — Seneca
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Destination guide

Travel to friendly Seneca

The lake and other outdoor surroundings create an inviting atmosphere in Seneca. Well-liked for its sporting events, university setting and boating, this city is both welcoming and scenic. Whether you're planning a family holiday, romantic stay or friends trip, vacation rentals offer features like full kitchens and laundry facilities for a more convenient stay.

Activities

Sightseeing in and around Seneca

Are you hoping to find things to do during your stay? Venture out of your vacation home and experience everything that makes Seneca a fun place to get away. Here are some of the most popular attractions to see, all within 30 miles (48.2 km) of the city center:

  • Walker Golf Course (6.4 mi / 10.4 km)
  • Keowee Key (10.3 mi / 16.6 km)
  • Easley Skate Center (21.2 mi / 34.1 km)
  • Cateechee Golf Club (25.2 mi / 40.5 km)
Natural features

Exploring the natural landscape of Seneca

Whether you're an adventurous traveler or just want to take in the scenery, Seneca is a great spot to appreciate mother nature. Here are a few of the area's most enchanting sights, all within 30 miles (48.2 km) of the city center:

  • South Carolina Botanical Gardens (7.4 mi / 11.9 km)
  • Lake Keowee (9.3 mi / 15 km)
  • Tugaloo Park (14.6 mi / 23.5 km)
  • Lake Hartwell (15.2 mi / 24.5 km)
  • Oconee State Park (15.3 mi / 24.6 km)
  • Devils Fork State Park (18.5 mi / 29.8 km)
How to get there

Traveling to and around Seneca

The nearest airport is in Greenville, SC (GSP-Greenville-Spartanburg Intl.), located 44.2 mi (71.1 km) from the city center.

How many vacation rentals are available around Seneca, SC?

Our 2021 property listings offer a large selection of 549 vacation rentals around Seneca. From 3 hotel rentals to 476 house rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

Can I rent Hotels in Seneca?

Yes, of course. Vrbo has 3 Hotels in Seneca. Our other popular types of vacation rentals in Seneca include:

  • Houses: 476 rentals available
  • Cabins: 63 rentals available
  • Cottages: 60 rentals available

But you can also enjoy a great stay in one of our other vacation rentals including Condos/Apartments and more.

Can I find a vacation rental with pool in Seneca?

Yes, you can select your preferred vacation rental with pool among our 72 vacation rentals with pool available in Seneca. Please use our search bar to access the selection of vacation rentals available.