Photo by Cindy Keese

Seneca vacation rentals

We found 594 vacation rentals — enter your dates for availability

Discover a selection of 199 homes, 10 apartments, and other vacation rentals in Seneca that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, vacation rentals have the amenities you need and want for your stay, which might include hot tub and a washer and dryer. No matter what you're looking for, you'll be sure to find a rental to meet everyone's needs, including a place that's non-smoking or offers accessibility.
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Find out more about Seneca

Find out more about Seneca

Why visit Seneca

  1. Outdoor Adventures: Seneca is perfect for hiking, fishing, and exploring scenic lakes and parks.
  2. Charming Neighborhoods: Experience friendly locals and explore picturesque neighborhoods that enhance your stay.
  3. Cultural Experiences: Discover historic colleges and cultural sites that reflect the area's rich heritage.
  4. Budget-Friendly Accommodations: Choose from a range of vacation rentals, including cozy condos and rustic cabins.
  5. Romantic Getaways: Enjoy the serene beauty of Seneca, ideal for couples seeking relaxation and romance.

Popular types of accommodation in Seneca

If you're exploring vacation rentals in Seneca, you're in for a treat! Our most popular options include houses, cozy cabins, and stylish apartments. Whether you're looking for affordable stays near Seneca Lake or luxurious apartments for a more upscale experience, we've got the perfect spot for you. Plus, if you're flying in, there are convenient options just a stone's throw from Seneca Airport. Discover your ideal getaway today!

  • Houses: These are the top choice for visitors to Seneca, offering spacious and comfortable accommodations ideal for families or groups.
  • Cabins: Perfect for those who crave a rustic escape, cabins provide a serene setting surrounded by nature.
  • Apartments: A convenient option for solo travelers or couples, these rentals offer amenities and a home-like atmosphere.
  • Condos: Offering a mix of comfort and luxury, condos are great for those seeking a stylish stay with added facilities.
  • Cottages: These quaint and charming spaces ensure a cozy retreat for a romantic getaway or peaceful vacation.**

Top attractions in Seneca

Seneca, South Carolina, offers a perfect blend of outdoor adventures and scenic beauty, making it ideal for romantic getaways and cultural experiences. Visitors can explore national and state parks, picturesque lakes, and historic colleges and universities. Whether you're looking to hike, relax by the water, or immerse yourself in local culture, Seneca has a variety of attractions to satisfy every traveler's interests.

  1. Clemson University: A historic institution with a vibrant campus atmosphere, known for its beautiful architecture and cultural events. Explore the lush grounds and immerse yourself in the rich traditions and academic spirit of this renowned university.
  2. Lake Keowee: A picturesque lake offering romantic settings and stunning outdoor scenery. Enjoy beach activities, boating, and hiking while soaking in the breathtaking views that make this area a perfect getaway for nature lovers.
  3. Memorial Stadium: A historic sports venue filled with energy and tradition, home to the Clemson Tigers. Experience the thrill of a college football game in this iconic stadium, where passionate fans create an unforgettable atmosphere.

Things to do recommended for couples

For a romantic escape in Seneca, consider a thrilling day at Ultimate Action Sports, just 16 miles away. Enjoy water sports together, embrace the adventure, and create unforgettable memories amidst breathtaking outdoor scenery. It's the perfect blend of excitement and romance for couples seeking adventure!

Things to do recommended for families

Your family will love the excitement at Littlejohn Coliseum, just 6 miles from Seneca. Enjoy the beauty of nature at Lake Hartwell State Park, 14 miles away, or relax in the serene surroundings of Keowee-Toxaway State Park, located 17 miles from town.

Things to do recommended for groups

Groups visiting Seneca can enjoy a round of golf at the Walker Golf Course or Keowee Key Golf Course for some outdoor fun. For a change of pace, head to Anderson Mall for shopping and entertainment, perfect for family bonding and relaxation.

What do I need to keep in mind when booking a vacation in Seneca

When planning your trip—whether you're traveling with a group, family, pets, or seeking extended stays—be sure to prioritize your filters accordingly. Here are some helpful Vrbo booking tips to assist you.

  • Traveling to Seneca with a group: Think about how many bedrooms you’ll require, along with amenities like a complete kitchen or outdoor areas for group gatherings. Luckily, you can easily filter for these options and more on Vrbo.
  • Traveling to Seneca with young kids: Traveling with young kids can be tough. It's important to prioritize their comfort and safety, along with suitable amenities like a private swimming pool. Additionally, think about how close you are to attractions that are friendly for families.
  • Taking your pets with you to Seneca: For many families, a trip wouldn't feel complete without their furry companion by their side. If this resonates with you, explore Vrbo listings that welcome pets. Many of these pet-friendly properties come equipped with feeding bowls and beds, ensuring that everyone feels comfortable and at home.
  • Planning for a long term stay visiting Seneca: If you're in search of vacation rentals that offer discounts for stays of a month or more, you've come to the right spot. By using the appropriate filters, you can effortlessly discover and save on monthly rentals. Don't forget to include features like a parking space, a well-equipped kitchen, or a private pool in your search criteria as well.

Where to stay in Seneca

Seneca, South Carolina, offers a delightful blend of outdoor adventures and stunning scenery, making it an ideal destination for families and couples alike. Explore the charming neighborhoods and nearby cities, where friendly locals create a warm atmosphere. Experience the beauty of nature while enjoying budget-friendly activities, and discover why this area is a hidden gem for those seeking relaxation and romance in a picturesque setting.

  • Highlands: Nestled 29 miles from Seneca, Highlands is a charming mountain town revered for its breathtaking scenery and outdoor adventures. Known for its romantic ambiance, this destination attracts couples and nature lovers alike. Enjoy a round of golf at the local country club or explore the trails of the nearby national state park. With its picturesque lake and stunning mountain views, Highlands offers a refreshing escape into nature, making it an ideal spot for hiking, picnicking, and simply soaking in the serene landscape.
  • Clemson: Located a mere 7 miles from Seneca, Clemson is a vibrant city that combines outdoor fun with cultural richness. Home to Clemson University, this city is bustling with energy and opportunities for exploration. Visitors can enjoy recreational areas and the lively atmosphere surrounding the university's historic campus. Don't miss the chance to visit the iconic stadium or take a stroll around the scenic lake. Clemson's diverse entertainment options and cultural experiences make it a fantastic destination for all types of travelers.
  • Keowee: Situated in close proximity to Seneca, Keowee is an outdoor paradise known for its romantic setting and stunning natural beauty. This area is perfect for those seeking adventure, with ample opportunities for recreation, including golf and water sports. Visitors can enjoy the serene beauty of the local lake and explore the nearby national park. The presence of the historic college university adds a unique charm to the area, blending education with the great outdoors. Keowee is a perfect retreat for those looking to relax and reconnect with nature.

Best time to go to Seneca

If you're planning a trip to Seneca, it's a good idea to check both the weather and property rates. The warmest month is July. Peak season runs in June to July and September, while off-peak times, like October to December tend to have fewer bookings and better deals.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January41.7°F (5.4°C)Light RainMostly SunnyAverageSlightly Low
February45.7°F (7.6°C)Light RainMostly SunnyAverageSlightly Low
March52.0°F (11.1°C)Light RainMostly SunnyAverageSlightly Low
April59.9°F (15.5°C)Light RainMostly SunnyAverageAverage
May68.2°F (20.1°C)Light RainMostly SunnyAverageSlightly High
June75.7°F (24.3°C)Light RainMostly SunnySlightly HighAverage
July79.2°F (26.2°C)Light RainMostly SunnySlightly HighAverage
August77.4°F (25.2°C)Light RainMostly SunnyAverageAverage
September72.1°F (22.3°C)Light RainMostly SunnySlightly HighSlightly High
October62.1°F (16.7°C)Light RainMostly SunnySlightly LowAverage
November51.4°F (10.8°C)Light RainMostly SunnySlightly LowSlightly High
December45.7°F (7.6°C)Light RainMostly SunnySlightly LowAverage

Booking with Vrbo is simple

Are you aiming to save on your upcoming journey? Being open to flexible travel dates can really help, as prices tend to vary. Additionally, booking a longer stay often leads to significant savings. To discover the perfect Vrbo property that fits your budget, take advantage of our filters to sort by price, location, and type of vacation rental.

Save more with One Key

When you reserve an eligible Vrbo for your group getaway, you'll receive OneKeyCash™ on the total booking amount. Being the organizer truly has its perks! Enroll in our OneKey rewards program to unlock exclusive savings for members and earn OneKeyCash™ on qualifying stays. Sign up today and begin your journey to earning rewards.

Vrbo Trips: Effortless planning

Vrbo's user-friendly Trip Board offers you a dedicated area to plan new adventures, pick up from where you last left off, or review and arrange your travel plans. You can easily find properties you've saved or booked under the categories of Potential, Upcoming, or Current Trips. To explore and utilize the Trip Boards, simply visit: https://www.vrbo.com/trips.

**Based on Vrbo properties booked during 2023 and 2024.

The friendly city of Seneca awaits you

The lake and surrounding scenery provide a peaceful ambiance to your vacation home in Seneca. Well-liked for its sporting events, university setting and boating, this city is both welcoming and scenic. Are you looking for specific amenities for your getaway? Many of our vacation rentals feature full kitchens and laundry facilities.

Activities and attractions in and around Seneca

Do you want to discover things to do in the city? Although it can be tempting to stay in your comfortable vacation rental, you'll want to check out everything that Seneca has to offer. These are some of the most popular attractions to explore, all within 30 miles (48.2 km) of the city center:

  • Walker Golf Course (6.4 mi / 10.3 km)
  • The Walker Course at Clemson University (6.7 mi / 10.8 km)
  • Keowee Key Golf Course (10.3 mi / 16.5 km)
  • Easley Skate Center (21.1 mi / 34 km)
  • Cateechee Golf Club (25.2 mi / 40.5 km)
  • Cross Creek Plantation Golf (2.6 mi / 4.2 km)

Exploring the natural landscape of Seneca

Whether you're looking for fun outdoor activities or just want to appreciate the scenery, Seneca is a great place to get outside. Here are a few of the area's most stunning sights, all within 30 miles (48.2 km) of the city center:

  • Keowee Reservoir (3.7 mi / 6 km)
  • Larry W. Abernathy Waterfront Park (6.6 mi / 10.6 km)
  • South Carolina Botanical Gardens (7.5 mi / 12 km)
  • Lake Keowee (9.3 mi / 14.9 km)
  • Villas at Foxwood Hills (11 mi / 17.7 km)
  • Stumphouse Mountain Tunnel (12.9 mi / 20.8 km)

Traveling to and around Seneca

The nearest airport is in Greenville-Spartanburg Intl. Airport (GSP), located 44.1 mi (71 km) from the city center.

Frequently asked questions

What is the best area to stay in Seneca when booking a vacation rental?
One of the more sought-after neighborhoods for a Seneca vacation home is Keowee. When you book your Vrbo vacation rental, you’ll have the entire place to yourselves. So you won’t have to share it with anyone other than your favorite people.
What is the most popular type of vacation rental accommodation in Seneca?
According to our data, cabins are the most desirable type of vacation rental in Seneca. But of course, everyone’s idea of an epic stay isn’t going to be the same. Vrbo has vacation homes of all shapes and sizes, and we’ll help you locate your ideal fit.
How much does it cost to rent a vacation rental in Seneca?
Length of stay, property type and season are among the factors that can affect the price of a vacation home. Simply enter your travel dates to find your perfect match. From cozy chalets to expansive villas, all Vrbo vacation rentals offer incredible value.
How much does it cost to rent a beach house in Seneca?
The average price for a vacation rental close to the beach in Seneca depends on when you’re traveling and the style and size of property you’re looking for. Find prices easily on Vrbo by entering your preferred travel dates and destination. Then use the filter tool to choose the number of bedrooms and amenities that you require, like air conditioning, WiFi and a pool.
Are there pet-friendly vacation rentals in Seneca?
Yes. There are. You can choose from 172 vacation rentals that allow pets in Seneca. Plenty of our pet-friendly vacation rentals even have a backyard for your four-legged pal to have fun in, special dog beds, complimentary treats and proximity to parks. Apply the “Pets allowed” filter to find your pawfect place on Vrbo.
Can I rent a house with a pool in Seneca?
Dig out your swimsuit and inflatable unicorn, because there are 34 houses with a private pool in Seneca. Settle in at one of these terrific vacation rentals and you’ll enjoy pool days every day. Simply enter your dates into Vrbo, then check the “pool” filter to find a place to make a splash!
What are popular rental amenities in Seneca?
When it comes to rental amenities that guests are looking for in Seneca, tennis, a nearby waterfront and a water view rank highest. With Vrbo vacation homes, you’ll discover options to match your taste and style, whether you’re vacationing with your partner, your family or even pets.
Are there large group vacation rentals in Seneca?
Seneca has 86 vacation properties that can fit 10 or more people. These stays come with enough space to enjoy good times with loved ones.
Are there vacation rentals in Seneca that welcome kids?
Seneca has 170 family-friendly vacation rentals to choose from. And securing a stay that welcomes kids is a cinch with our “Properties good for families” filter. Besides having the entire place to yourselves, you’ll get access to conveniences and perks like living rooms, yards and private pools.
Are there one-bedroom vacation rentals in Seneca?
Yes, Seneca has 10 one-bedroom rentals on offer. Often situated in popular spots due to their smaller size, a one-bedroom vacation property is great if you’re getting away with your partner or a pal. And with comforts such as full kitchens and more privacy than a standard hotel, you’ll be able to kick back while exploring this amazing destination.
Can I find two-bedroom vacation rentals in Seneca?
Seneca has 17 two-bedroom vacation rentals to choose from. Find a vacation home with all the comfort and privacy you’re looking for at a price that’s hard to resist on Vrbo.
Are there vacation rentals with WiFi in Seneca?
Whether you want to stay in touch with world events, reply to emails or surf social networks, there are 96 vacation homes with WiFi in Seneca. Check the “WiFi” box when searching on Vrbo and stay connected on your getaway.
How can I find vacation rentals with air conditioning in Seneca?
Decide on your travel dates and then use our filters to locate vacation rentals with ac in Seneca on Vrbo. With 166 air-conditioned properties available here, you can look forward to a cool and comfy stay.
How old do you have to be to rent a vacation rental in Seneca?
You should check with the Seneca vacation home you’d like on Vrbo as age restrictions vary. However, it’s typically 16, 18 or 21.
How long can I rent a vacation rental in Seneca for?
It’s down to the Seneca property. To browse a list of options offering extended stays, just enter your dates and guest number into Vrbo’s search page. Enjoy having the whole place to yourself, along with the comforts of home like air conditioning, a kitchen and outdoor spaces to run around in. Keep your eyes peeled for long-term stays that offer discounted weekly or monthly prices.
Does Vrbo offer discounts for vacation homes in Seneca?
In Seneca, you’ll find some incredible bargains and discounts for weekly and monthly discounts on vacation rentals, as well as newly listed homes on Vrbo. Whether you’re after a mini vacay or a longer stay, we have a variety of options that’ll suit your style.

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