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Six Mile, SC

Six Mile vacation rentals

We found 272 vacation rentals — enter your dates for availability

Discover a selection of 272 vacation rentals in Six Mile that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including WiFi and swimming pools. Prices start at $174 per night, and houses and cabins are popular options for a stay in Six Mile. Either way, you'll find a rental for everyone's needs.
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Find the perfect vacation rental in Six Mile

Lakefront Home on Lake Keowee in Gated Community, 20 Minutes to Clemson

Sleeps 17 · 6 Bedrooms · 6 Bathrooms
$750 avg/night
(42)

40 Acre Cabin -farm experience with fishing, near Lake Keowee and Clemson, SC

Sleeps 4 · 1 Bedroom · 1 Bathroom
$174 avg/night
(19)

Lake Keowee Retreat w/lots of entertainment space: Only 9 miles from Clemson!

Sleeps 10 · 4 Bedrooms · 3 Bathrooms
$272 avg/night
(6)

Waterfront Lake Keowee chalet with Gorgeous 180° Lake Views 15 min from Clemson!

Sleeps 8 · 4 Bedrooms · 3 Bathrooms
$317 avg/night
(32)

Greene Lodge on Lake Keowee, lakefront w/2 docks, close to Clemson University

Sleeps 20 · 6 Bedrooms · 4 Bathrooms
$695 avg/night
(73)

NEW! Lakefront Six Mile Retreat w/ Hot Tub & Dock!

Sleeps 12 · 4 Bedrooms · 3 Bathrooms
$255 avg/night
(9)

Search 272 vacation rentals

Reviews are in, families love these Six Mile properties
Stayed Apr 2021

Nice property. Beautiful view!

Overall the place was great. Wish the fireplace was working, especially since it took up the main wall with an actual view. If it’s going to replace well deserved windows, it should be functional. Shannah’s communication was spot on and everything yo...

Michelle B.
Michelle B.
Stayed Apr 2021

Beautiful cabin on beautiful lake!

One of the most beautiful lakes I have ever had the pleasure of visiting and I’m from Minnesota, Land of 10,000 lakes! Cabin was excellent! The beds are super comfortable, even more so than my new bed at home. Just keep in mind that nothing is child ...

Devin J.
Devin J.
Stayed Mar 2021

Photos Don’t Do It Justice!

This rental is so cozy and beautiful. We all agreed it was even more attractive in person than the photos show. It’s very well kept, everything worked properly, and is decorated with class and care. There were 8 of us, 4 adults and 4 children (toddle...

Dana B.
Dana B.

FAIRPORT, NY

Stayed Mar 2021

Great place and awesome hosts

This property was a great place to stay. There were 3 couples and we all loved it here. The space was great and very comfortable. It was chilly at night and we really enjoyed the heater on the lower level screened porch as well as the fire pit on the...

Mary jane M.
Mary jane M.
Stayed Mar 2021

Great spot on the lake

All around a great place to stay on lake Keowee. Property was well designed and fit our family of 4 nicely. Owners set up a great experience, from a clean and well designed unit, to a clear guidebook with instructions on how to operate everything, to...

Ian M.
Ian M.
Stayed Mar 2021

Great Retreat

Great location, house was perfect and had everything we needed. We spent most of the time in the pavilion down by the water. The host provides plenty of activities with multiple water toys. The sand beach with fire pit is a nice touch (fire wood not ...

Jeffrey D.
Jeffrey D.

Greenville, SC

Stayed Mar 2021

Beautiful Property with beautiful view

Our family truly enjoyed our 3 night stay. Very clean. Quiet. Relaxing. Enjoyed the pool table and screened porches. Plenty of space. A few minor features that were advertised but not accessible so that was a bit disappointing. Restaurants and grocer...

Amelia T.
Amelia T.
Stayed Mar 2021

Incredible lake home

From the first contact, the owners were great communicators and continued all throughout the stay including when we accidentally locked ourselves out! The home is beautiful, clean and well-appointed. The amenities are both natural (the lake is incr...

Leanne A.
Leanne A.
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How many vacation rentals are available around Six Mile?

Our 2021 property listings offer a large selection of 272 vacation rentals around Six Mile. From 232 house rentals to 26 cabin rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

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