Mytilene vacation rentals

We found 75 vacation rentals — enter your dates for availability

Discover a selection of 15 homes, 23 apartments, and other vacation rentals in Mytilene that are perfect for your trip. Vacation rentals provide the best amenities for your family, friends, or furry companion, like WiFi and a washer and dryer. What you'll find is a rental to meet everyone's needs, including options that are accessible or non-smoking.

Find out more about Mytilene

The waterfront setting of Mytilene is ready to explore

Take a vacation to Mytilene and enjoy the area's museums, monuments and churches. This city's island views, seaside and architecture draw many visitors. If you need more space to accommodate a family vacation or friends trip, rental homes often come with separate dining areas and spacious living rooms.

Exploring the natural features in Mytilene

Whether you're an adventurous traveler or just want to appreciate the scenery, Mytilene is a great place to spend some time outside. These are a few of the area's most enchanting features, all within 30 miles (48.2 km) of the city center:

  • Thermi Beach (6.3 mi / 10.1 km)
  • Altinova Beach (12.2 mi / 19.7 km)
  • Badavut Beach (12.8 mi / 20.5 km)
  • Plomari Beach (12.8 mi / 20.6 km)
  • Sarimsakli Beach (13 mi / 21 km)
  • Fame Beach (13.9 mi / 22.4 km)

Transportation options to and around Mytilene

Fly into Mytilene (MJT-Mytilene Intl.), the closest airport, located 4 mi (6.4 km) from the city center.

Frequently asked questions

What is the best area to stay in Mytilene when booking a vacation rental?
When considering a vacation rental in Mytilene, the capital of Lesbos, a popular area to stay is the vibrant waterfront district. This area is known for its picturesque views of the harbour and the Aegean Sea, making it an ideal spot for those who enjoy a scenic backdrop. The bustling promenade is lined with charming cafes and restaurants, where you can savour local delicacies while watching the world go by.

Another excellent choice is the Old Town, characterised by its narrow cobbled streets and traditional architecture. Here, you will find the impressive Byzantine Castle, which offers a glimpse into the island's rich history and provides stunning panoramic views from its ramparts. The Old Town is also home to various shops and local markets, superb for those looking to immerse themselves in the local culture.

In terms of vacation rentals, the waterfront district offers a range of properties, from modern apartments to quaint houses, suiting different preferences and budgets. The Old Town also boasts a selection of charming accommodations, allowing visitors to enjoy the special environment of this historic area.
How much does it cost to rent a vacation home in Mytilene?
Prices for vacation rentals in Mytilene vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're travelling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Mytilene to more spacious homes.
Are there any discounts for Mytilene vacation house rentals?
You can find great discounts on house rentals in Mytilene on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
Can I find long-stay vacation rentals in Mytilene?
A long-stay vacation rental in Mytilene is the best way to experience local living. Plus, you can make the most of long-stay discounts. Long-stay discounts are applied automatically when you enter your travel dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.
Are there any Mytilene vacation rentals with parking?
Vrbo offers a wide selection of vacation rentals in Mytilene with parking available—perfect for families or travellers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
When is the best time to visit Mytilene for a vacation rental?
September is the best time to visit Mytilene for a vacation rental, as it marks the tail end of the peak season, which runs from August to October. During this month, visitors can relish in the pleasant weather while avoiding the summer crowds, allowing for a more relaxed exploration of this beautiful island.

The warm Mediterranean climate during September typically sees temperatures ranging from 20 to 30 degrees Celsius, providing ideal conditions for outdoor activities such as hiking, swimming, and sightseeing around the charming harbour and historical sites. You can stroll through the picturesque streets of Mytilene, sampling local cuisine or visiting the ancient ruins without feeling rushed.

For those seeking a more budget-friendly option, December offers a quieter experience. While the weather is cooler, with temperatures dropping to around 10 to 15 degrees Celsius, it provides a unique opportunity to enjoy the island's culture and serenity, particularly for travellers interested in a more authentic local experience during the off-peak months.

In summary, if you prefer vibrant summer energy and bustling activities, late September strikes the superb balance of warmth and tranquillity. However, if you're inclined towards a more peaceful retreat, exploring Mytilene in December can offer its own unique charm.
How early should I book a Mytilene vacation rental?
Book your Mytilene vacation rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your vacation rental, the better the price.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
What are the top attractions in Mytilene?
In Mytilene, visitors can engage in a rich tapestry of history and culture. The central area is adorned with beautiful neoclassical buildings and offers attractions like the Archaeological Museum of Mytilene, which showcases artefacts from the island's ancient past. Nearby, the imposing Mytilene Castle sits atop a hill, providing panoramic views of the city and the sea, and is a must-visit for history enthusiasts.

The picturesque waterfront promenade is superb for a leisurely stroll, lined with cafes and restaurants where one can enjoy local delicacies. Additionally, the vibrant local market area, known as the Agora, is an excellent spot to experience the local lifestyle and pick up unique souvenirs.

For those interested in nature, the nearby Petrified Forest is a fascinating site located just outside the city, offering a glimpse into the island's prehistoric past.
Can I change or cancel my Mytilene home rental booking on Vrbo?
To find Mytilene vacation rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travellers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cosy cabin or a beach house, you can turn your space into a standout destination, become a host and let Vrbo handle the heavy lifting to help you thrive.

Earn a Premier Host badge by providing quick, reliable communication and consistently delivering outstanding guest experiences.
Are all fees included in the Mytilene vacation rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.
What is VrboCare™ and how does it work?
Vrbo's mission is to help guests relax, reconnect, and enjoy precious time together. With VrboCare™, you can have peace of mind knowing you're protected and that if something goes wrong, we will do our best to make it right.

If a significant issue arises that your host can't resolve, we'll help you address it, find a similar property, or get your reservation refunded if applicable. That's our promise. If a home is significantly different than listed, we'll get you into a new space that meets your needs and makes it right, or if a host cancels before your stay, you have a dedicated support team to get you into a similar home as applicable.
What can I expect from Vrbo customer service and VrboCare™ support?
Your peace of mind is our priority. Whether you're planning your trip or have already finished your stay, VrboCare™ is here to support you every step of the way. For urgent situations, such as last-minute cancellations, booking issues, or potential fraud, Vrbo customer service is available 24/7 to support you every step of the way.

Vrbo also offers support via live chat through our Help Centre, where you can find helpful resources on bookings, payments, property management, and safety, making it easy to get instant answers to many common questions.
Can I plan a group trip on Vrbo?
Vrbo's Trip Planner makes organising group trips easy and stress-free. Whether you're planning with friends or coordinating a large group, you can collaborate in one place, save and share properties, vote on favorites, and build the perfect itinerary together.