Syracuse villas

We found 679 villas — enter your dates for availability

Find spaces that suit your style

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  • More quality time

    From booking to staying, the whole process is simple and enjoyable

  • All the privacy of home

    Enjoy full kitchens, laundry, pools, yards and more

  • More for less

    More space, more privacy, more amenities — more value

Frequently asked questions

Are there any vacation villa rentals in Syracuse?
Browse our 679 villa rentals in Syracuse that are often set in beautiful and exclusive locations. Whether you want to stay in Ortigia, Santa Lucia, Acradina or another well-known neighborhood, you'll discover the ideal villa on Vrbo.
How much does it cost to stay in a villa rental in Syracuse?
Prices vary depending on length of stay, time of year and exact location, so enter your trip details to discover what's available. Whatever your style or budget, Vrbo has villa rentals in Syracuse for guests of every type.
When is the best time to rent a villa in Syracuse?
The best time to visit Syracuse depends on things like activities that you want to try and your favorite season. With average temperatures ranging between 17ºC (63ºF) and 20ºC (68ºF), May is a popular month to get a villa rental in this part of Province of Syracuse. Want to really experience the community and culture of this destination? Check for major events or festivals and arrange your villa rental around them.
Where can I rent a Syracuse villa with great views?
Villa rentals with views of historic areas are just one of the types of stays you can book in Syracuse. If you're looking for spacious villas that offer vistas worth remembering, you'll discover them on Vrbo.
Can I book a luxury villa in Syracuse?
Equipped with a host of amenities like swimming pools, beautiful courtyards and advanced in-home entertainment, Vrbo's luxurious villa rentals in Syracuse promise a deluxe travel experience. Look forward to enjoying the very best in modern and comfortable furnishings, plenty of room and a setting that ensures privacy and tranquility for you and your guests.
What are the top things to do in Syracuse?
One of the first things to do after booking your villa rental is to pack your itinerary with enjoyable activities. There's plenty of them in Syracuse, with top-rated family-friendly attractions including Cathedral of Syracuse, Temple of Apollo and Museo Archeologico Regionale Paolo Orsi.
Why should I book my villa vacation with Vrbo?
With 24/7 customer support, your peace of mind is guaranteed when you book through Vrbo. From the minute you secure your villa rental to even after your vacation is over, we're with you at every step. It's all part of our Book with Confidence Guarantee. Plus, we also have an easy and secure payment process and flexible cancellation policies