Downtown Isle of Palms holiday rentals

We found 410 holiday rentals — enter your dates for availability
Select from 28 houses, 167 flats and other holiday rentals to find the perfect place for your stay in Downtown Isle of Palms. Whether you're travelling with a group or just with your pet, holiday rentals have the best amenities for spending time at your holiday home, such as Wi-Fi and cable TV. No matter what you're looking for, you'll be sure to find a property to rent for everyone's needs, including a place that's non-smoking or offers accessibility.

Holiday rentals with weekly discounts – Downtown Isle of Palms

Showing deals for:20 Nov - 27 Nov

Kitchen and dining Beach Dream, 2605 Cameron Blvd, Isle of Palms, SC | IOP Escapes
screened porch Beach Dream, 2605 Cameron Blvd, Isle of Palms, SC | IOP Escapes
screened porch Beach Dream, 2605 Cameron Blvd, Isle of Palms, SC | IOP Escapes
Chef's Kitchen, Beach Dream, 2605 Cameron Blvd, Isle of Palms, SC | IOP Escapes
Exceptional
(18 reviews)

5 BR Luxury Home w Pool | 3 Min Walk to Beach

Isle of Palms

7% off
S$18,030
for 7 nights, 1 home
S$2,576 per night
includes taxes & fees
5 BR Luxury Home w Pool | 3 Min Walk to Beach
Kitchen - WhatUp Beach! | 26 22nd Ave | Isle of Palms, SC | IOP Escapes
Kitchen - WhatUp Beach! | 26 22nd Ave | Isle of Palms, SC | IOP Escapes
Terrace/patio
WhatUp Beach! | 26 22nd Ave | Isle of Palms, SC | IOP Escapes
Exceptional
(11 reviews)

6 BR | 6.5 BA | Sleeps 12 | Dog-Friendly | Heated Plunge Pool | Walk to Beach

Isle of Palms

7% off
S$23,992
for 7 nights, 1 home
S$3,427 per night
includes taxes & fees
6 BR | 6.5 BA | Sleeps 12 | Dog-Friendly | Heated Plunge Pool | Walk to Beach
Aerial View of IOP Life
Large Kitchen with walk out to Pool Deck
Welcome to IOP Life at 27 22nd Avenue
Large Open Pool Deck
Exceptional
(26 reviews)

6BR 6BA Isle of Palms Vacation Rental Pet Friendly, Luxury Coastal Retreat

Isle of Palms

7% off
S$24,171
for 7 nights, 1 home
S$3,453 per night
includes taxes & fees
6BR 6BA Isle of Palms Vacation Rental Pet Friendly, Luxury Coastal Retreat
A private boardwalk to the beach
1140 Ocean Blvd. welcomes guests with beautiful oceanfront views
An oceanfront patio for morning coffee 208 1140 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Open-concept living and dining area 208 1140 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Exceptional
(103 reviews)

Beautiful Oceanfront 4BR Condo in the Heart of IOP with Pool.

Isle of Palms

7% off
S$9,089
for 7 nights, 1 apartment
S$1,298 per night
includes taxes & fees
Beautiful Oceanfront 4BR Condo in the Heart of IOP with Pool.
Pool
Terrace/patio
Dining
Interior
Exceptional
(14 reviews)

4 BR IOP Beach Rental with Private Pool & Hot Tub

Isle of Palms

7% off
S$11,321
for 7 nights, 1 home
S$1,617 per night
includes taxes & fees
4 BR IOP Beach Rental with Private Pool & Hot Tub
Primary King Suite | Starfish | Oceanview 101 | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Oceanview | Starfish | Oceanview 101 | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Back porch views of the ocean | Starfish | Oceanview 101 | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Beach Gate | Starfish | Oceanview 101 | 1116 Ocean Blvd, Isle of Palms, SC | IOP Escapes
Exceptional
(85 reviews)

Pet Friendly | 3BR First Floor Oceanfront Condo | Heart of IOP

Isle of Palms

7% off
S$7,432
for 7 nights, 1 apartment
S$1,062 per night
includes taxes & fees
Pet Friendly | 3BR First Floor Oceanfront Condo | Heart of IOP
Interior
Walkway with lights
Living area
Living area
Exceptional
(105 reviews)

"Cottage by the Sea"

Isle of Palms

7% off
S$2,973
for 7 nights, 1 home
S$425 per night
includes taxes & fees
"Cottage by the Sea"
Balcony, Pool, & Ocean
Balcony & Ocean
Owners Bedroom
1140 Ocean Blvd Complex & Gate
Exceptional
(78 reviews)

Spectacular Ocean Front Condo 1140 OB Blvd #108 4 BR / 3 BA IOP, SC, Sleeps 12+

Isle of Palms

7% off
S$8,073
for 7 nights, 1 apartment
S$1,153 per night
includes taxes & fees
Spectacular Ocean Front Condo 1140 OB Blvd #108 4 BR / 3 BA IOP, SC, Sleeps 12+
Dining | Palms Postcard | 1006 Ocean Blvd, Dunescape 103, Isle of Palms, SC | IOP Escapes
Living Room view of beach | Palms Postcard | 1006 Ocean Blvd, Dunescape 103, Isle of Palms, SC | IOP Escapes
Exterior Dunescape Isle of Palms, SC | IOP Escapes
View from back porch | Palms Postcard | 1006 Ocean Blvd, Dunescape 103, Isle of Palms, SC | IOP Escapes
Exceptional
(10 reviews)

FIrst Floor End Unit 3 BR Oceanfront Condo w/ Pool | Isle of Palms Beach Rental

Isle of Palms

7% off
S$9,248
for 7 nights, 1 apartment
S$1,321 per night
includes taxes & fees
FIrst Floor End Unit 3 BR Oceanfront Condo w/ Pool | Isle of Palms Beach Rental
Living Room | Susu's Sea Cabin | 238C 1300 Ocean Blvd | Isle of Palms, SC | IOP Escapes8C | Isle of Palms, SC | IOP Escapes
Welcome to Susu's Sea Cabin | 238C 1300 Ocean Blvd | Isle of Palms, SC | IOP Escapes
Sea cabins from the ocean | Susu's Sea Cabin | 238C 1300 Ocean Blvd | Isle of Palms, SC | IOP Escapes
Community pool | Susu's Sea Cabin | 238C 1300 Ocean Blvd | Isle of Palms, SC | IOP Escapes
Exceptional
(13 reviews)

Oceanfront 2nd Floor Luxury Condo - Community Pool & Fishing Pier!

Isle of Palms

7% off
S$3,092
for 7 nights, 1 apartment
S$442 per night
includes taxes & fees
Oceanfront 2nd Floor Luxury Condo - Community Pool & Fishing Pier!
View of Condo from Kitchen | 211C Oceanside Villas | Isle of Palms SC | IOP Escapes Villa Solea
Kitchen and Island | 211C Oceanside Villas | Isle of Palms SC | IOP Escapes Villa Solea
Living Room | 211C Oceanside Villas | Isle of Palms SC | IOP Escapes Villa Solea
Oceanside Villas Aerial View Near The Beach | 211C Oceanside Villas | Isle of Palms SC | IOP Escapes Villa Solea
Exceptional
(10 reviews)

Newly Renovated | 2 BR Condo w Pool | Steps to Beach w Pier Access

Isle of Palms

7% off
S$3,786
for 7 nights, 1 apartment
S$541 per night
includes taxes & fees
Newly Renovated | 2 BR Condo w Pool | Steps to Beach w Pier Access
Sea Cabins Northern Aerial View, Isle of Palms, SC
Sea Cabins Southern Aerial View, Isle of Palms, SC
Beach Views from Sea Cabins 230B Balcony, Isle of Palms, SC | IOP Escapes
Aerial View of Isle of Palms, SC | IOP Escapes
Exceptional
(19 reviews)

1 Bedroom Oceanfront Condo Sea Cabin 230B | Pool | Renovated in 2024

Isle of Palms

7% off
S$3,196
for 7 nights, 1 apartment
S$457 per night
includes taxes & fees
1 Bedroom Oceanfront Condo Sea Cabin 230B | Pool | Renovated in 2024
Living room & dining | Crescent Moon, 301 Oceanview | Isle of Palms, SC | IOP Escapes Vacation Rentals
Private Beach Access | Crescent Moon, 301 Oceanview | Isle of Palms, SC | IOP Escapes Vacation Rentals
Aerial View of Isle of Palms, SC | IOP Escapes
Living Room | Crescent Moon, 301 Oceanview | Isle of Palms, SC | IOP Escapes Vacation Rentals
Exceptional
(203 reviews)

Largest 1BR/1BA in IOP | Pool | Pet Friendly

Isle of Palms

7% off
S$3,472
for 7 nights, 1 apartment
S$496 per night
includes taxes & fees
Largest 1BR/1BA in IOP | Pool | Pet Friendly
Pool
County park with facilities, playground & beach access
View from Ocean Blvd
Kitchen with new cabinets and new stone countertops
Exceptional
(152 reviews)

Thrifty with WiFi and Video Streaming

Isle of Palms

7% off
S$1,994
for 7 nights, 1 apartment
S$285 per night
includes taxes & fees
Thrifty with WiFi and Video Streaming
Sea Cabins Condominiums on The Ocean
Sea Cabins Condominiums on The Ocean
Sleeper Sofa in Living Room | IOP Escapes The Admiral | Sea Cabins 307A | Top Floor Luxury Oceanfront Condo
Entrance Hallway | IOP Escapes The Admiral | Sea Cabins 307A | Top Floor Luxury Oceanfront Condo
Exceptional
(17 reviews)

1 BR Top Floor Isle of Palms Oceanfront Sea Cabin

Isle of Palms

7% off
S$3,129
for 7 nights, 1 apartment
S$447 per night
includes taxes & fees
1 BR Top Floor Isle of Palms Oceanfront Sea Cabin
Sea Cabin Fishing Pier
Large family room with lots of seating, ceiling fan, and balcony access. Sea Cabin 208A, Isle of Palms, SC | IOP Escapes
Aerial view of Isle of Palms, SC | IOP Escapes
Aerial view of Sea Cabin Complex and Pier, Isle of Palms, SC | IOP Escapes
Exceptional
(72 reviews)

Sea Cabin 208 | 1 Bedroom Oceanfront Condo | Pool | Just Renovated

Isle of Palms

7% off
S$3,136
for 7 nights, 1 apartment
S$448 per night
includes taxes & fees
Sea Cabin 208 | 1 Bedroom Oceanfront Condo | Pool | Just Renovated
Living area
Exterior
View from Morgan's Creek Bar & Grill at Isle of Palms Marina
Living area
Exceptional
(167 reviews)

Isle Of Palms Condo, half block to beach, enter with combo, private entrance.

Isle of Palms

7% off
S$2,824
for 7 nights, 1 apartment
S$403 per night
includes taxes & fees
Isle Of Palms Condo, half block to beach, enter with combo, private entrance.
Living Room & Kitchen at Sea Cabin 214A, Isle of Palms, SC | IOP Escapes
Living Room at Sea Cabin 214A, Isle of Palms, SC | IOP Escapes
Kitchen at Sea Cabin 214A, Isle of Palms, SC | IOP Escapes
Aerial View Sea Cabins Isle of Palms, SC
Exceptional
(14 reviews)

Sea Cabin 214A | Oceanfront 1 Bedroom Condo | Pool | Brand New

Isle of Palms

7% off
S$3,173
for 7 nights, 1 apartment
S$453 per night
includes taxes & fees
Sea Cabin 214A | Oceanfront 1 Bedroom Condo | Pool | Brand New
Dining Area Dunescape 101 IOP Escapes
Oceanfront Pool view Dunescape IOP Escapes
Kitchen with stainless steel appliances and prep island with seating. Dunescape 101 IOP Escapes
1006 Ocean Blvd., Unit #101 welcomes visitors with a warm family room, comfort seating, a flat-screen television, and balcony access!
Exceptional
(63 reviews)

In the Heart of IOP; Luxury Oceanfront 3BR Condo - Dunescape - Island Jammin

Isle of Palms

7% off
S$7,475
for 7 nights, 1 apartment
S$1,068 per night
includes taxes & fees
In the Heart of IOP; Luxury Oceanfront 3BR Condo - Dunescape - Island Jammin
Dining Area | | | 104A Oceanside Villas | Isle of Palms SC | IOP Escapes
Living Room | | 104A Oceanside Villas | Isle of Palms SC | IOP Escapes
Kitchen || | 104A Oceanside Villas | Isle of Palms SC | IOP Escapes
Hallway |104A Oceanside Villas | Isle of Palms SC | IOP Escapes
Wonderful
(10 reviews)

Newly Renovated | 2 BR Condo w Pool | Steps to Beach w Pier Access

Isle of Palms

7% off
S$3,621
for 7 nights, 1 apartment
S$517 per night
includes taxes & fees
Newly Renovated | 2 BR Condo w Pool | Steps to Beach w Pier Access
Interior
Ocean View from Balcony
Exterior
Entry to Municipal Parking Lot
Excellent
(20 reviews)

Thrifty with WiFi and Video Streaming

Isle of Palms

7% off
S$2,564
for 7 nights, 1 apartment
S$366 per night
includes taxes & fees
Thrifty with WiFi and Video Streaming
Aerial View of Isle of Palms, SC | IOP Escapes
Aerial View of Sea Cabins On the Ocean, Isle of Palms, SC
Sea Cabins Northern View, Isle of Palms, SC
Porch | Coastal Calm | Sea Cabins 310A, Isle of Palms, SC | IOP Escapes
Exceptional
(26 reviews)

1 BR Top Floor Isle of Palms Oceanfront Condo | Pool | Free Wifi & Parking

Isle of Palms

7% off
S$3,170
for 7 nights, 1 apartment
S$453 per night
includes taxes & fees
1 BR Top Floor Isle of Palms Oceanfront Condo | Pool | Free Wifi & Parking
  • Peace of mind

    Our Book with Confidence guarantee gives you 24/7 support
  • More quality time

    From booking to staying, the whole process is simple and enjoyable
  • All the privacy of home

    Enjoy full kitchens, laundry, pools, gardens and more
  • More for less

    More space, more privacy, more amenities — more value

Frequently asked questions

Can I find holiday rentals in Downtown Isle of Palms?
Yes, there are holiday rentals close to the most popular sights in Downtown Isle of Palms, or you can select a more secluded option if you're looking for a relaxing stay.
How many holiday rentals will I find in Downtown Isle of Palms?
Expedia has 28 holiday rentals for your stay in Downtown Isle of Palms.
What can I see and do in Downtown Isle of Palms?
Isle of Palms County Park and Isle of Palms Beach are a couple of lovely local spots to get outside and enjoy nature. Front Beach and Windjammer (The) are other places to visit while you're in town.
What are holiday rentals like in Downtown Isle of Palms?
Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Downtown Isle of Palms. Holiday rentals provide amenities like WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can offer a sense of privacy away from shared hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a holiday rental than in a traditional hotel, which makes a holiday rental a great choice for a family trip or a small group gathering.