Photo by Rick Tuers
Guadalupe District vacation rentals
We found 288 vacation rentals — enter your dates for availability
Discover a selection of 58 homes and other vacation rentals in Guadalupe District that are perfect for your trip. Whether you’re staying in a vacation home with your kids and pets or just with friends, you'll find the best amenities for hanging out with the people that matter most, which might include a hot tub and a washer and dryer. Whatever you're looking for, you'll find a rental that has what everyone needs, including accessible or non-smoking choices.
Vacation rentals with weekly discounts - Guadalupe District
Showing deals for:Oct 10 - Oct 17
Image gallery for Feel at Home , all sanitized, 6 walkable blocks from Santa Fe Plaza.
9.69.6 out of 10 rating
Exceptional
(27 reviews)
Feel at Home , all sanitized, 6 walkable blocks from Santa Fe Plaza.
Santa Fe, NM
8% off
$2,271 for 7 nights
$2,271 for 7 nights
Price is $324
$324
All fees included
Image gallery for Beautiful Home Near Plaza
9.49.4 out of 10 rating
Exceptional
(6 reviews)
Beautiful Home Near Plaza
Santa Fe, NM
8% off
$2,502 for 7 nights
$2,502 for 7 nights
Price is $357
$357
All fees included
Image gallery for Contemporary Style with Old World Charm
9.89.8 out of 10 rating
Exceptional
(11 reviews)
Contemporary Style with Old World Charm
Santa Fe, NM
8% off
$1,704 for 7 nights
$1,704 for 7 nights
Price is $243
$243
All fees included
Image gallery for Casa Del Mar- King Bed - Patio -Railyard - 3BR
9.89.8 out of 10 rating
Exceptional
(8 reviews)
Casa Del Mar- King Bed - Patio -Railyard - 3BR
Santa Fe, New Mexico
10% off
$3,042 for 7 nights
$3,042 for 7 nights
Price is $435
$435
All fees included
Image gallery for Heart of Downtown Oasis & Steps from the Plaza
9.69.6 out of 10 rating
Exceptional
(33 reviews)
Heart of Downtown Oasis & Steps from the Plaza
Santa Fe, NM
9% off
$3,059 for 7 nights
$3,059 for 7 nights
Price is $437
$437
All fees included
Image gallery for Private Casita 3 Houses From The Railyard District - Newly Renovated!
9.69.6 out of 10 rating
Exceptional
(19 reviews)
Private Casita 3 Houses From The Railyard District - Newly Renovated!
Santa Fe, NM
8% off
$1,151 for 7 nights
$1,151 for 7 nights
Price is $164
$164
All fees included
Image gallery for Historic Charm Meets Modern Elegance
9.89.8 out of 10 rating
Exceptional
(30 reviews)
Historic Charm Meets Modern Elegance
Santa Fe, NM
9% off
$2,532 for 7 nights
$2,532 for 7 nights
Price is $362
$362
All fees included
Image gallery for Timeless Charm Steps from Santa Fe Plaza & Museums - Casa Sueno
8.68.6 out of 10 rating
Excellent
(25 reviews)
Timeless Charm Steps from Santa Fe Plaza & Museums - Casa Sueno
Santa Fe, NM
8% off
$1,601 for 7 nights
$1,601 for 7 nights
Price is $229
$229
All fees included
Find spaces that suit your style
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Condo/Apartment
Cabin
Cottage
Villa
Chalet
Find properties near top attractions in Guadalupe District
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Find the best place to stay - Guadalupe District
Historic Charm Meets Modern Elegance
Sleeps 4 · 2 bedrooms · 2 bathrooms
9.89.8 out of 10
Exceptionalexceptional
30 reviews(30 reviews)
Beautiful Santa Fe Home w/ Modern Updates - Walk to Downtown & Railyards
Sleeps 6 · 3 bedrooms · 2 bathrooms
8.08.0 out of 10
Very Goodvery good
14 reviews(14 reviews)
Adobe House Close to Downtown, Opera, and Historic Plaza
Sleeps 10 · 3 bedrooms · 1+ bathroom
9.69.6 out of 10
Exceptionalexceptional
10 reviews(10 reviews)
Daisy Casita | Great Location + Close to Santa Fe Plaza!
Sleeps 4 · 2 bedrooms · 1 bathroom
9.69.6 out of 10
Exceptionalexceptional
16 reviews(16 reviews)
Alto Adventures - Walk to the Plaza
Sleeps 4 · 2 bedrooms · 2 bathrooms
9.89.8 out of 10
Exceptionalexceptional
17 reviews(17 reviews)
Quiet Condo w/ Private Yard & Balcony - 1 Block from Railyard
Sleeps 4 · 2 bedrooms · 2 bathrooms
9.69.6 out of 10
Exceptionalexceptional
85 reviews(85 reviews)
Top rated rentals - Guadalupe District
A wonderful house
1010 out of 10
Exceptionalexceptional
178 reviews(178 reviews)
We stayed here for the third time, and we completely enjoyed it again. The house is very comfortable and nice, and we enjoyed sitting outside in the lovely yard. The location is great, too.
Lisa L.
Stayed Jun 2025
Wonderful!
1010 out of 10
Exceptionalexceptional
44 reviews(44 reviews)
We had such a wonderful time. The house is beautiful and serene, and decorated with so much love and care. It is located on a lovely quiet street, but very close to everything central. Lynn is an excellent host with attention to detail. The courtyard was so nice too, for morning coffee and hearing the birds sing. Thank you, I look forward to coming back in the future!
Elli C.
Stayed May 2025
In nice neighborhood
1010 out of 10
Exceptionalexceptional
3 reviews(3 reviews)
Nice location in Santa Fe great property
Manuel A.
Stayed May 2025
Exceeded Expectations
1010 out of 10
Exceptionalexceptional
1 review(1 review)
Such a cute clean place.Folk art wherever Iooked. Management easy to work with
Joseph G.
Stayed May 2025
Santa Fe getaway
1010 out of 10
Exceptionalexceptional
3 reviews(3 reviews)
Perfect place for me-easy walking distance to most venues; well appointed, quiet and hosts were very responsive. Thank you!
trudy t.
Stayed Mar 2025
Xmas in SantaFe
1010 out of 10
Exceptionalexceptional
8 reviews(8 reviews)
Very spacious and airy. Well equipped kitchen. Quiet neighborhood within easy walking distance of Railyard and Plaza. Great value.
John F.
Stayed Dec 2024
Cozy stay in a great location.
1010 out of 10
Exceptionalexceptional
3 reviews(3 reviews)
I fully enjoyed my stay and would recommend to anyone looking for an extended stay in Santa Fe. They even left me Christmas Cookies.
Aaron K.
Stayed Nov 2024
Santa Fee Immersion
1010 out of 10
Exceptionalexceptional
279 reviews(279 reviews)
Casita De Soledad felt like a perfect Santa Fe escape and like home from the moment we pulled into the carport.
The property surpassed expectations, delivering more than its description suggested. All furniture was comfortable. The decor was very tasteful, no, perfect, and site appropriate. Little hospitalities like coffee, tea, shampoo and conditioner were much appreciated.
The house information book, supplied guide books and brochures opened the city and the neighborhood. Nearby, walkable restaurants and galleries were abundant. We loved the location.
Communication with the owners was easy. We couldn't have been more pleased. We will recommend to all friends traveling to Santa Fe and , hopefully return ourselves in the near future.
Lorna F.
Stayed Oct 2024
Peace of mindOur Book with Confidence guarantee gives you 24/7 support
All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
More for lessMore space, more privacy, more amenities — more value
Find out more about Guadalupe District
Frequently asked questions
What is the most popular type of vacation rental accommodation in Guadalupe District?
Condos are the most popular kind of vacation rental in Guadalupe District, according to our data. Even if you have a different idea about what you'd like, Vrbo has properties in many sizes and shapes. Explore our options to find your perfect pad.
How much does it cost to rent a vacation rental in Guadalupe District?
Season, length of stay and property type are some things that can determine the price of a vacation home. Simply enter your travel dates to find your dream escape. From quaint country cottages to plush villas, all Vrbo vacation rentals provide incredible value.
How much does it cost to rent a beach house in Guadalupe District?
The average price for a vacation home near the beach in Guadalupe District depends on when you'll be there and the style and size of property you're looking for. You can easily find prices on Vrbo by entering the dates you'll be traveling. Then use the filters to pick the number of bedrooms and amenities that you require, like air conditioning, a pool and WiFi.
Are there pet-friendly vacation rentals in Guadalupe District?
Yes. You'll have a choice of 87 vacation rentals that allow pets in Guadalupe District. Several of our pet-friendly vacation rentals even come with an outdoor space for your furry pal to run around in, complimentary treats, doggie beds and proximity to parks. Apply the "Pets allowed" filter to find a pad that'll get tails wagging on Vrbo.
What are popular rental amenities in Guadalupe District?
Some of the most popular rental amenities guests are looking for in Guadalupe District include a chef, a fireplace and tennis. Whether you're taking a trip with friends, family or even pets, Vrbo vacation properties come with the best amenities for fun and relaxation with your loved ones.
Are there large group vacation rentals in Guadalupe District?
Guadalupe District has two vacation homes that can accommodate 10 or more people. These properties come with all the space you need to enjoy good times with loved ones.
Are there vacation rentals in Guadalupe District that welcome kids?
Guadalupe District has 85 family-friendly vacation rentals to choose from. And securing a stay that welcomes children is super easy with Vrbo's "Properties good for families" filter. In addition to having the entire place to yourselves, you'll get perks and conveniences such as dining rooms, private pools and yards.
What are the top attractions for families in Guadalupe District?
Enjoy a day out with all the family at SITE Santa Fe. This wonderful attraction is located near the heart of Guadalupe District.
Are there one-bedroom vacation rentals in Guadalupe District?
Yes, you can take your pick from 31 one-bedroom rentals in Guadalupe District. Whether you're looking for a townhouse or a cabin, our one-bedroom rentals are perfect if you don't require a huge amount of space. One of the major perks of having your own digs? You'll never have to share your adventure with strangers.
Can I find two-bedroom vacation rentals in Guadalupe District?
Guadalupe District has 38 two-bedroom properties to choose from. Go for a vacation home with all the space and comfort you need at a price you'll love on Vrbo.
Are there vacation rentals with WiFi in Guadalupe District?
Whether you'd like to keep up with the latest headlines, write a few emails or surf your social networks, there are 29 vacation homes with WiFi in Guadalupe District. Check the "WiFi" box when searching on Vrbo and stay connected on your vacation.
How can I find vacation rentals with air conditioning in Guadalupe District?
Guadalupe District has 78 vacation rentals where you'll be able to kick back in air-conditioned comfort. To book a property on Vrbo that offers this amenity, choose your travel dates and use the convenient filters to select the "air conditioning" box.
How old do you have to be to rent a vacation rental in Guadalupe District?
The minimum age allowed can differ between properties on Vrbo, so be sure to check the rules of the vacation home in Guadalupe District you're considering. But normally, it's 16, 18 or 21.
How long can I rent a vacation rental in Guadalupe District for?
The length of time you can rent a vacation rental in Guadalupe District is up to the property. Just enter your selected travel dates to view a list of options offering extended stays. With plenty of features like air conditioning and full kitchens, as well as some offering weekly or monthly discounted prices, you're sure to discover a terrific place to call your home away from home in Guadalupe District.
Does Vrbo offer discounts for vacation homes in Guadalupe District?
Overnight trip or extended vacation, Vrbo has some fantastic deals and discounts in Guadalupe District to match your style and budget. Take a look at our weekly and monthly discounts on vacation rentals, or see what's just been added with one of our newly listed homes. Whatever you're after, you'll find the ideal place to stay --- without blowing your budget.