Panacea holiday lettings

We found 313 holiday rentals — enter your dates for availability

Select from 158 homes, 25 cottages and other holiday rentals in Panacea to find one that's perfect for your trip. Holiday homes provide the best amenities for your stay with friends, family or just your pet, such as parking and a hot tub. Whatever you're looking for, you'll find a property to rent to meet everyone's needs, including a place that is accessible or non-smoking.

Holiday rentals with weekly discounts - Panacea

Showing deals for:20 Feb - 27 Feb

Image gallery for Nothing Between You, the Gulf of Mexico and Amazing Sunrises!

View of the cottage from the West - Decks and porch face east and south
9.8 out of 10, Exceptional, (72 reviews)
Exceptional
(72 reviews)

Nothing Between You, the Gulf of Mexico and Amazing Sunrises!

Crawfordville, FL

8% off
Price is £1,108
for 7 nights, 1 cottage
£158 per night
includes taxes & fees
Nothing Between You, the Gulf of Mexico and Amazing Sunrises!

Find spaces that suit your style

Why people love visiting relaxing Panacea

The beaches and wildlife provide a pleasant backdrop to your holiday home in Panacea. Well known for its dolphin watching, seafood restaurants and fishing, this relaxing city won't disappoint. With a holiday rental, you get a home away from home – many rentals offer full kitchens and outdoor grills for some home cooking.

Activities and attractions in Panacea

Do you want to discover top things to see and do in the city? You'll be sure to enjoy Panacea for its dolphin viewing and fishing. Although it can be tempting to stay in your comfortable holiday rental, you'll want to check out everything that makes Panacea a fun spot to go on holiday. Here are some of the most popular attractions to explore, all within 30 miles (48.2 km) of the city centre:

  • St. James Bay Golf Club (13 mi / 21 km)
  • Wildwood Golf Club (7.3 mi / 11.7 km)
  • Gulf Specimen Public Aquarum (0.8 mi / 1.2 km)

Exploring the natural landscape of Panacea

Whether you're an active traveller or just want to appreciate the scenery, Panacea is a great place to spend some time outside. Here are some of the area’s most enchanting sights, all within 30 miles (48.2 km) of the city centre:

  • Mashes Sand Beach (5.1 mi / 8.2 km)
  • Shell Point Beach (6.7 mi / 10.8 km)
  • Alligator Point Beach (8.3 mi / 13.3 km)
  • Bald Point State Park (9 mi / 14.6 km)
  • Apalachicola National Forest (16.3 mi / 26.2 km)
  • St. Marks National Wildlife Refuge (17.2 mi / 27.7 km)

Seasonal weather averages in Panacea

If warm-weather activities are high on your list, July, August, June and September are the hottest months to visit, when temperatures average 27°C.

How to get to and around Panacea

The nearest airport is in Tallahassee, FL (TLH-Tallahassee Intl.), located 25.5 mi (41.1 km) from the city centre.

Frequently asked questions

What is the best area to stay in Panacea when booking a holiday rental?
When considering a holiday rental in Panacea, Florida, the best area to stay is near the coastline, particularly around the scenic Bald Point State Park. This picturesque neighbourhood offers a range of properties, from charming cottages to spacious beachfront homes, allowing visitors to immerse themselves in the natural beauty of the region. With its stunning views of the Gulf of Mexico and easy access to pristine beaches, this area is great for those looking to unwind and enjoy the outdoors.

A highlight of staying near Bald Point State Park is the opportunity to explore the diverse ecosystems, including salt marshes and coastal forests. The park is a haven for wildlife enthusiasts, providing excellent birdwatching opportunities and a chance to spot dolphins in the nearby waters. Additionally, the proximity to the quaint town of Panacea means you can easily enjoy local dining options and experience the warm hospitality of the area.

Another appealing neighbourhood is the area surrounding the Apalachicola National Estuarine Research Reserve. Staying here offers a unique blend of recreational activities and natural exploration. Visitors can enjoy kayaking, fishing, and hiking, making it an ideal spot for those who appreciate the great outdoors. The reserve is not only a beautiful space but also a point of interest for those keen on learning about the local ecosystem.
How much does it cost to rent a holiday home in Panacea?
Prices for holiday rentals in Panacea vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're traveling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Panacea to more spacious homes. To get the best value, book early and take advantage of Vrbo's free rewards program.
Are there any discounts for Panacea holiday house rentals?
You can find great discounts on house rentals in Panacea on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
Where are the best areas for renting a beach house in Panacea?
For renting a beach house in Panacea, Florida, the coastal area near the Apalachicola National Estuarine Research Reserve is an excellent choice. This region offers access to beautiful sandy shores and serene natural landscapes, making it ideal for travellers seeking a relaxing beach getaway. Many holiday rentals in this area come equipped with amenities such as private decks, outdoor grilling facilities, and fully stocked kitchens, allowing guests to enjoy meals while taking in the picturesque views.

Additionally, the nearby St. George Island is a prominent destination for beach house rentals, featuring properties that often include spacious living areas, access to beach equipment, and outdoor showers for rinsing off after a day spent by the water. These rentals typically provide a blend of comfort and convenience, suiting both families and groups.
What is the most popular type of holiday rental accomodation in Panacea?
In Panacea, holiday houses are the most popular type of rental, with around 154 available throughout the area. These properties often feature spacious layouts, multiple bedrooms, fully equipped kitchens, and outdoor spaces where guests can enjoy the warm Florida weather. Many holiday houses are situated close to natural attractions like the Ochlockonee River and nearby beaches, making them superb for families or groups looking to explore the region. Additionally, there are about 24 charming cottages and several condos and apartments that offer a cozier stay, often featuring amenities like pools or communal areas.
Are there any family house rentals in Panacea?
In Panacea, Florida, there are numerous family-friendly house rentals available, with around 133 options to choose from. This charming coastal area is known for its picturesque scenery and access to outdoor activities, making it an excellent choice for families. Many of these homes offer spacious living areas and fully equipped kitchens, allowing families to prepare meals together.
Can I rent a holiday home with a pool or hot tub in Panacea?
In Panacea, Florida, there are several holiday homes available for rent that include pools and hot tubs, with around 37 options to choose from. This charming coastal town offers a laid-back atmosphere and proximity to beautiful beaches, making it an ideal getaway for travellers seeking relaxation. Many of these properties feature private pools, hot tubs, and spacious outdoor areas, great for soaking up the sun or enjoying evening gatherings. Additionally, you'll often find fully equipped kitchens, allowing for convenient self-catering during your stay.
Can I find long-stay holiday rentals in Panacea?
A long-stay holiday rental in Panacea is the best way to experience local living. Plus, you can make the most of long-stay discounts. Long-stay discounts are applied automatically when you enter your travel dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.
Are there pet-friendly house rentals in Panacea?
In Panacea, there are a variety of pet-friendly house rentals available, offering a welcoming environment for travellers with furry companions. Many of these rentals feature amenities such as spacious outdoor areas, fully equipped kitchens, and comfortable living spaces, superb for families or groups looking to unwind.
Are there any remote work holiday rentals in Panacea?
In Panacea, Florida, there are plenty of remote work holiday rentals available, with around 173 properties suiting those looking to blend work and leisure. Many of these accommodations are equipped with essential amenities for remote work, including Wi-Fi, dedicated desk spaces, and comfortable office chairs. Some properties also offer additional features such as laptop workspaces and computer monitors, providing a conducive environment for productivity. To help narrow your search, insert your dates and apply the "WiFi" filter on Vrbo.
Are there any Panacea holiday rentals with parking?
Vrbo offers a wide selection of holiday rentals in Panacea with parking available—perfect for families or travellers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
What are popular rental amenities in Panacea?
In Panacea, popular holiday rental amenities include fully equipped kitchens, allowing guests to prepare their own meals with ease. Most rentals come with essential cookware, dishware, and utensils, as well as modern appliances such as refrigerators and microwaves. These conveniences enhance the home-like experience while exploring the natural beauty of the Florida coast.
When is the best time to visit Panacea for a holiday rental?
The most popular time to visit Panacea is during the peak season from April to June. This vibrant period attracts holidaymakers looking to soak up the sun, enjoy outdoor adventures, and relax by the beautiful Gulf Coast. The warm temperatures, often reaching the mid to high 20s Celsius, create an inclusive setting for beach activities and water sports, making it an ideal time for families and groups seeking a fun getaway.

April marks the beginning of this bustling season, with visitors enjoying mild weather and fewer crowds compared to the height of summer. As you explore the stunning landscapes, you can partake in activities such as kayaking in the nearby waterways or birdwatching in the wildlife-rich area, all while appreciating the scenic beauty that Panacea has to offer.

For those looking for a more budget-friendly option, consider visiting in November. This month provides a lovely opportunity to experience the quieter side of Panacea, where you can enjoy pleasant temperatures and fewer tourists while still taking in the natural beauty of the area. The less crowded beaches and tranquil setting create a superb backdrop for leisurely strolls and peaceful relaxation.
How early should I book a Panacea holiday rental?
Book your Panacea holiday rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your holiday rental, the better the price.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
Can I change or cancel my Panacea home rental booking on Vrbo?
To find Panacea holiday rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travellers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cosy cabin or a beach house, you can turn your space into a standout destination, become a host and let Vrbo handle the heavy lifting to help you thrive.Earn a Premier Host badge by providing quick, reliable communication and consistently delivering outstanding guest experiences.
Are all fees included in the Panacea holiday rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.
What is VrboCare™ and how does it work?
Vrbo's mission is to help guests relax, reconnect, and enjoy precious time together. With VrboCare™, you can have peace of mind knowing you're protected and that if something goes wrong, we will do our best to make it right as applicable.If a significant issue arises that your host can't resolve, we'll help you address it, find a similar property, or get your reservation refunded if applicable. That's our promise. If a home is significantly different than listed, we'll get you into a new space that meets your needs and makes it right, or if a host cancels before your stay, you have a dedicated support team to get you into a similar home as applicable.
What can I expect from Vrbo customer service and VrboCare™ support?
Your peace of mind is our priority. Whether you're planning your trip or have already finished your stay, VrboCare™ is here to support you every step of the way. For urgent situations, such as last-minute cancellations, booking issues, or potential fraud, Vrbo customer service is available 24/7 to support you every step of the way.Vrbo also offers support via live chat through our Help Centre, where you can find helpful resources on bookings, payments, property management, and safety, making it easy to get instant answers to many common questions.
Can I plan a group trip on Vrbo?
Vrbo's Trip Planner makes organising group trips easy and stress-free. Whether you're planning with friends or coordinating a large group, you can collaborate in one place, save and share properties, vote on favorites, and build the perfect itinerary together.

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