Santee vacation rentals

We found 200 vacation rentals — enter your dates for availability

Discover a selection of 9 homes and other vacation rentals in Santee that are perfect for your trip. Vacation homes offer the best amenities for you and your friends, family, or even pets, such as a hot tub and a washer and dryer. At the end of the day, you'll be sure to find a rental for everyone's needs, including accessible or non-smoking choices.

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Find out more about Santee

Why visit Santee

  • Stunning outdoor adventures: Santee is perfect for nature lovers, featuring beautiful national and state parks, serene lakes, and picturesque islands.
  • Romantic getaway: The peaceful atmosphere makes Santee an ideal destination for couples seeking a romantic escape.
  • Welcoming accommodations: Choose from charming cabins, cozy cottages, or spacious vacation homes to suit your needs.
  • Budget-friendly options: Enjoy a variety of activities and local spots without breaking the bank.
  • Friendly locals: Experience warm hospitality and create memorable connections with the community.

Popular types of accommodation in Santee

Planning a getaway to Santee? You're in for a treat. Discover a variety of welcoming accommodations, including houses, charming cabins, and cozy cottages. Whether you prefer a spacious house, a friendly rental, or a suite, Santee has something for everyone. Dive into your adventure with the perfect place to relax after a day of exploration.

  • Houses: The top pick for visitors in Santee, these homes offer ample space and comfort, perfect for families or groups.
  • Cabins: A favourite for those seeking a rustic escape, cabins provide a serene connection to nature.
  • Cottages: These quaint and charming accommodations are ideal for a warm, intimate getaway.
  • Condos: A practical choice, condos offer convenience and amenities for a pleasant stay.
  • Apartments: Budget-friendly and centrally located, apartments are great for solo travellers or couples.**

Top attractions in and around Santee

Santee, South Carolina, is perfect for outdoor enthusiasts and couples seeking a romantic getaway. The region boasts stunning scenery, with popular attractions such as national and state parks, picturesque islands, and serene lakes. Whether you're looking for beach adventures or tranquil nature experiences, Santee offers a delightful blend of activities that will make your vacation unforgettable.

  • Santee State Park: Experience adventure and stunning scenery in this expansive park. Enjoy hiking, fishing, and camping amidst the beautiful landscapes and outdoor vibes.
  • Taw Caw Creek: A picturesque lake perfect for a romantic getaway, featuring lovely beaches and serene scenery. Ideal for picnics, swimming, and enjoying nature's beauty.
  • Orangeburg County Library Mentor Branch: A welcoming library offering a glimpse into local culture and family-friendly resources. Great for relaxing, reading, and engaging with the community.

Things to do recommended for couples

Escape to Santee, South Carolina, where you can enjoy a leisurely boat ride on Lake Marion or take a romantic stroll in Santee State Park. Delight in a cozy dinner at a lakeside restaurant, soaking in the beautiful sunset views together. Perfect for a memorable couple's getaway.

Things to do recommended for families

Families visiting Santee can explore the serene Santee National Wildlife Refuge, just 6.4km away, offering wellness and relaxation vibes. Additionally, Taw Caw Creek Park, located 14.5km from Santee, provides a peaceful outdoor setting perfect for family picnics and nature walks.

Things to do recommended for groups

Enjoy a round of golf at Santee Cooper Country Club, Santee National Golf Club, or venture 25.7km to Wyboo Golf Club. Each offers a fantastic outdoor atmosphere, perfect for group camaraderie and friendly competition.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

What do I need to keep in mind when booking a vacation in Santee

When planning your trip—whether you're traveling with a group, family, pets, or seeking extended stays—it's important to prioritize your preferences. Here are some helpful Vrbo booking tips for you.

  • Traveling to Santee with a group: Think about how many bedrooms you require, along with amenities like a full kitchen or outdoor areas for group gatherings. Thankfully, you can easily refine your search to include all of these features, and so much more, on Vrbo.
  • Traveling to Santee with young kids: Traveling with young children can present its challenges. It's essential to prioritize their comfort and safety, along with finding suitable amenities like a private swimming pool. Additionally, considering your closeness to family-friendly attractions is highly recommended.
  • Taking your pets with you to Santee: For many families, a trip isn't truly complete without their furry companion. If this resonates with you, consider exploring Vrbo properties that welcome pets. Most of these pet-friendly accommodations offer feeding bowls and beds, ensuring that every member of the family feels comfortable and at home.
  • Planning for a long term stay visiting Santee: If you're in search of vacation rentals offering great deals for stays of a month or more, you've come to the right spot. By using the appropriate filters, you can effortlessly discover and save on monthly rentals. Don't forget to include amenities like a parking space, a well-equipped kitchen, or even a private pool in your search criteria.

Where to stay near Santee

Santee, South Carolina, offers a delightful blend of outdoor adventures and serene landscapes, perfect for a romantic getaway or a family-friendly vacation. Explore the tranquil lakes and spacious backyards that define the area, all while enjoying the sunny weather. With its welcoming atmosphere and budget-friendly options, Santee invites you to discover unique local spots and create memorable experiences amidst friendly locals.

  • Summerton: Located a mere 17.7km from Santee, Summerton is a charming city that beckons outdoor enthusiasts and those seeking scenic vistas. The area is ideal for a romantic getaway, boasting numerous recreational opportunities. Visitors can enjoy golfing at well-maintained courses or explore the stunning natural landscapes of nearby lakes and the national state park. With its tranquil environment, Summerton provides a perfect backdrop for picnics and leisurely strolls, making it an excellent stop for those looking to connect with nature.
  • Vance: Just 8.0km from Santee, Vance is a delightful city that offers a mix of outdoor adventure and picturesque scenery. It's a popular destination for couples and nature lovers alike, with plenty of options for recreational activities, including golf on scenic courses. The nearby lakes and national state park provide perfect spots for fishing, hiking, and enjoying the serene beauty of the region. Vance’s tranquil atmosphere invites visitors to unwind and appreciate the great outdoors.
  • Elloree: Situated 9.7km away from Santee, Elloree is a quaint city that embodies the spirit of outdoor exploration and natural beauty. Known for its romantic ambiance, Elloree features ample recreational areas and golf courses for visitors to enjoy. Nearby attractions include breathtaking lakes and the expansive national park, perfect for hiking or birdwatching. With its charming small-town feel, Elloree offers a welcoming escape for those looking to relax and immerse themselves in the stunning South Carolina landscape.

Best time to go to Santee

If you're planning a trip to Santee, it's a good idea to check both the weather and property rates. The warmest month is July. Peak season runs in March to April and July, while off-peak times, like October to December tend to have fewer bookings and better deals.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January47.3°F (8.5°C)Light RainMostly SunnyAverageSlightly Low
February51.4°F (10.8°C)Light RainMostly SunnyAverageSlightly Low
March56.8°F (13.8°C)Light RainMostly SunnySlightly HighSlightly Low
April64.4°F (18.0°C)Light RainMostly SunnySlightly HighAverage
May72.0°F (22.2°C)Light RainMostly SunnyAverageAverage
June78.6°F (25.9°C)Light RainMostly SunnyAverageSlightly High
July81.5°F (27.5°C)Light RainMostly SunnySlightly HighSlightly High
August79.9°F (26.6°C)Light RainMostly SunnyAverageSlightly High
September75.4°F (24.1°C)Light RainMostly SunnyAverageAverage
October66.4°F (19.1°C)Light RainMostly SunnySlightly LowAverage
November56.1°F (13.4°C)Light RainMostly SunnySlightly LowAverage
December51.3°F (10.7°C)Light RainMostly SunnySlightly LowAverage

Booking with Vrbo is simple

Looking to save on your next trip? Consider being flexible with your travel dates, as prices can fluctuate significantly. Also, opting for a longer stay can often lead to substantial savings. To discover the ideal Vrbo property that fits your budget, make use of our filters to search by price, location, and type of vacation rental.

Vrbo Trips: Planning as easy as it gets

Vrbo’s Trip Board offers a handy platform for you to plan new adventures, continue from where you last stopped, or manage your travel arrangements. You can easily find all your saved or booked properties organized under categories such as Potential, Upcoming, or Current Trips. To begin exploring Trip Boards, simply visit: https://www.vrbo.com/en-ca/trips.

**Based on Vrbo properties bookings.

The friendly area of Santee awaits your stay

The lake and surrounding scenery provide a peaceful ambiance to your vacation home in Santee. Travelers to this welcoming city praise the restaurants, golfing and fishing. Whether you're planning a family vacation, friends trip or romantic retreat, Vrbo has a great selection of vacation homes. Many rentals come with a full kitchen and separate dining area, perfect if you need a space for entertaining.

Activities and attractions in Santee

Do you want to discover attractions to visit while you're in the area? Venture out of your cozy vacation rental and experience everything that makes Santee a fun spot to vacation. Here are some of the top attractions to put on your list, all within 30 miles (48.2 km) of the city center:

  • Santee Cooper Country Club (0.6 mi / 1 km)
  • Santee National Golf Club (0.8 mi / 1.4 km)
  • Wyboo Golf Club (16.3 mi / 26.3 km)
  • St. George Country Club (22.6 mi / 36.4 km)

Exploring the natural features in Santee

Whether you're looking for adventure or just want to appreciate the scenery, Santee is a great place to spend some time outside. These are some of the area's most enchanting natural features, all within 30 miles (48.2 km) of the city center:

  • Lake Marion (7.9 mi / 12.7 km)
  • Taw Caw Creek (8.5 mi / 13.7 km)
  • Santee National Wildlife Refuge (4.4 mi / 7 km)
  • Goat Island (9.4 mi / 15.1 km)
  • Edisto Memorial Gardens (22.7 mi / 36.5 km)
  • Pine Island (7.4 mi / 12 km)

Transportation to and around Santee

The nearest airport is in Columbia Metropolitan Airport (CAE), located 49 mi (78.8 km) from the city center.

Frequently asked questions

What is the best area to stay in Santee when booking a vacation rental?
When considering a vacation rental in Santee, South Carolina, the area surrounding Lake Marion is particularly appealing. This scenic neighbourhood offers a wonderful blend of natural beauty and recreational opportunities, making it an ideal spot for a relaxing getaway. Visitors can enjoy fishing, boating, and picnicking by the lakeside, with the tranquil waters providing a superb backdrop for outdoor activities.

Another excellent area to consider is Santee State Park, which is renowned for its stunning landscapes and abundant wildlife. Staying near the park allows easy access to hiking trails and nature walks, offering a chance to immerse oneself in the local flora and fauna. This area is popular among those who appreciate outdoor adventures and the serenity of nature.
How much does it cost to rent a vacation home in Santee?
Prices for vacation rentals in Santee vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're travelling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Santee to more spacious homes.
Are there any discounts for Santee vacation house rentals?
You can find great discounts on house rentals in Santee on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
Where are the best areas for renting a beach house in Santee?
For renting a beach house in Santee, South Carolina, travellers should focus on the nearby Lake Marion area, which is renowned for its scenic waterfront properties. The Santee State Park region offers a variety of vacation rentals that provide direct access to the lake, superb for those looking to enjoy water activities such as fishing, boating, and swimming. Many properties in this area come equipped with essential amenities like private docks, outdoor grilling areas, and spacious decks for entertaining while taking in the serene views.

Additionally, the town of Santee itself features a selection of charming cottages and larger family homes, often with features like fully equipped kitchens, laundry facilities, and comfortable living spaces. Some rentals may also include access to community amenities such as swimming pools or golf courses, making them suitable for a range of vacation experiences.
What is the most popular type of vacation rental accomodation in Santee?
In Santee, condos are the most popular type of vacation rental, with around 91 available throughout the area. These condos typically offer modern amenities, including fully equipped kitchens, comfortable living areas, and access to community facilities such as swimming pools and fitness centres. Many are conveniently located near Lake Marion, providing easy access for fishing, boating, and enjoying the lakeside scenery.
Are there any family house rentals in Santee?
In Santee, South Carolina, there are numerous family-friendly vacation rentals available, with around 93 options to choose from. This charming locale is particularly well-known for its proximity to Lake Marion, where families can enjoy fishing, boating, and picnicking. Many properties in the area provide spacious living areas, well-equipped kitchens for preparing family meals, and outdoor spaces superb for children to play.
Can I rent a vacation home with a pool or hot tub in Santee?
In Santee, South Carolina, there are plenty of vacation homes available for rent that feature pools and hot tubs, with around 93 options to choose from. This charming area is known for its beautiful lakes and outdoor recreational activities, making it an ideal destination for families and groups seeking relaxation and adventure.
Can I find long-stay vacation rentals in Santee?
A long-stay vacation rental in Santee is the best way to experience local living. Plus, you can make the most of long-stay discounts. Long-stay discounts are applied automatically when you enter your travel dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.
Are there pet-friendly house rentals in Santee?
In Santee, there are several pet-friendly house rentals available, offering a welcoming environment for both travellers and their furry companions. Many of these vacation homes are conveniently located near Lake Marion, providing easy access to outdoor activities such as fishing, boating, and hiking.

The rentals typically feature amenities like spacious living areas, fully equipped kitchens, and outdoor spaces where pets can enjoy some fresh air. Additionally, some properties may include private yards or patios, ideal for pet owners.
Are there any remote work vacation rentals in Santee?
In Santee, South Carolina, there are numerous remote work vacation rentals available, with around 102 options to choose from. This area is known for its beautiful lakes and serene surroundings, making it an ideal spot for both relaxation and productivity. Many of the properties come equipped with essential amenities for remote work, including dedicated desk spaces, comfortable chairs, and high-speed Wi-Fi, ensuring that guests can stay connected while enjoying their stay. To help narrow your search, insert your dates and apply the "WiFi" filter on Vrbo.
Are there any Santee vacation rentals with parking?
Vrbo offers a wide selection of vacation rentals in Santee with parking available—perfect for families or travellers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
What are popular rental amenities in Santee?
In Santee, popular rental amenities include kitchens, which allow guests to prepare their own meals, and shared pools for relaxation and recreation. Many properties also offer stunning lake views, enhancing the natural beauty of the area. Additionally, outdoor patios provide a lovely space to enjoy the warm weather and scenic surroundings.
When is the best time to visit Santee for a vacation rental?
April is the most popular time to visit Santee, South Carolina, as the weather is pleasantly warm and great for outdoor activities. This month falls within the peak season, which spans from March to May, attracting travellers who seek a blend of relaxation and adventure. With temperatures typically ranging in the high teens to low 20s Celsius, visitors can comfortably explore the stunning Santee State Park, go fishing on Lake Marion, or enjoy a round of golf at one of the local courses.

The spring months offer a vibrant atmosphere, particularly in April when the flora is in full bloom, enhancing the natural beauty of the area. This is an ideal time for sightseeing, whether you're wandering through local parks or indulging in the rich culture and cuisine of the region.

For those looking for a more budget-friendly option, consider visiting in November. While this month is quieter, it still offers pleasant temperatures and the opportunity to enjoy the scenic landscapes without the hustle and bustle of peak season. You'll find that November provides a chance to appreciate the tranquillity of Santee, with fewer tourists around to disturb your peaceful getaway.
How early should I book a Santee vacation rental?
Book your Santee vacation rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your vacation rental, the better the price.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
Can I change or cancel my Santee home rental booking on Vrbo?
To find Santee vacation rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travellers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cosy cabin or a beach house, you can turn your space into a standout destination, become a host and let Vrbo handle the heavy lifting to help you thrive.Earn a Premier Host badge by providing quick, reliable communication and consistently delivering outstanding guest experiences.
Are all fees included in the Santee vacation rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.
What is VrboCare™ and how does it work?
Vrbo's mission is to help guests relax, reconnect, and enjoy precious time together. With VrboCare™, you can have peace of mind knowing you're protected and that if something goes wrong, we will do our best to make it right.If a significant issue arises that your host can't resolve, we'll help you address it, find a similar property, or get your reservation refunded if applicable. That's our promise. If a home is significantly different than listed, we'll get you into a new space that meets your needs and makes it right, or if a host cancels before your stay, you have a dedicated support team to get you into a similar home as applicable.
What can I expect from Vrbo customer service and VrboCare™ support?
Your peace of mind is our priority. Whether you're planning your trip or have already finished your stay, VrboCare™ is here to support you every step of the way. For urgent situations, such as last-minute cancellations, booking issues, or potential fraud, Vrbo customer service is available 24/7 to support you every step of the way.Vrbo also offers support via live chat through our Help Centre, where you can find helpful resources on bookings, payments, property management, and safety, making it easy to get instant answers to many common questions.
Can I plan a group trip on Vrbo?
Vrbo's Trip Planner makes organising group trips easy and stress-free. Whether you're planning with friends or coordinating a large group, you can collaborate in one place, save and share properties, vote on favorites, and build the perfect itinerary together.

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