East End vacation rentals
We found 911 vacation rentals — enter your dates for availability
Discover a selection of 8 homes and other vacation rentals in East End that are perfect for your trip. Vacation rentals offer the best amenities for your stay with friends, family, or just your pet, like parking and a TV. You'll be able to choose a rental that has what everyone needs, including places that are non-smoking or accessible.
Find spaces that suit your style
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Condo/Apartment
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Cottage
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Find properties near top attractions in East End
Find the best place to stay - East End
The Lovebird-sleeps 3! Great value on Sanibel-walk to dining, shops and Historic East End Lighthouse
Sleeps 4 · 1 bedroom · 1 bathroom
Sanibel-Style on the East End! Walk to restaurants and the lighthouse. NEW!
Sleeps 3 · 1 bedroom · 1 bathroom
Seahorse Suites #4. A Perfect Beach Getaway!
Sleeps 4 · 2 bedrooms · 1 bathroom
Beachfront Condo + Heated Pool, Hot Tub, Tennis + Walk to Dining
Sleeps 6 · 2 bedrooms · 2 bathrooms
Luxury Villa Lighthouse Across from the Beach
Sleeps 6 · 2 bedrooms · 1+ bathroom
Amazing Direct Ocean Gulf Front Beach Views Condo, pool and hot tub are open!
Sleeps 6 · 2 bedrooms · 2 bathrooms
Top rated rentals - East End
Wonderful Peace
Absolutely fantastic! The pictures does not do this place justice. It is beautiful and so peaceful. We have never been to a cleaner place outside and in. The island did not disappoint. Everywhere we went people were so pleasant. We will be returning!
Cynthia H.
Stayed Jul 2026
Beautiful A4 - steps from beach
Rating Details:
The property manager was very helpful.
The vacation rental was spotless.
I was very happy with the location.
I was very satisfied with the condition of the vacation rental.
Overall, I recommend this vacation rental.
Reviewer Comments:
Beautiful condo in Sanibel! Excellent location and beautifully renovated. The second bedroom has both a twin and a full bed. Wonderful accommodations for a family of five! We LOVE LOVE Sanibel and can’t wait to return.
Carianne K.
Stayed Jul 2026
Amazing experience
Our stay at Sandalfoot was amazing. The apartment is well stocked and super comfortable. They provide beach chairs and toys and the view of the beach is lovely. We will definitely be back!
Sara N.
Stayed Jul 2026
Location? Location? Location!
Our week-long stay at sandalfoot in 2b1 was truly enjoyable! The screened in patio on ground level was so convenient. Just steps away from the boardwalk to the beach and a beautiful view of the pool and gorgeous landscaping. I was so impressed at the pristine landscaping and grounds. Great detail and attention was taken to this entire condo area. I highly recommend this condo and working with this company. It was easy, communication was extremely good, the condo was beautifully decorated and very clean. We look forward to coming back to Sanibel and will definitely want to book this location again
Amy A.
Stayed Jun 2026
Love it here!
Rating Details:
The property manager was very helpful.
The vacation rental was spotless.
I was very happy with the location.
I was more than satisfied with the condition of the vacation rental.
Overall, I recommend this vacation rental.
Reviewer Comments:
My family and I used to come to Sanibel moorings when I was a little girl up until highschool. We hadn’t been back in years and this stay was exactly what I remembered — quiet, calm, relaxing and just wonderful. We can’t wait to make this a family tradition again!
Vanessa T.
Stayed Jun 2026
Long Weekend in the Beach
The property and the unit were very nice and provided perfect space and amenities for a great weekend retreat on the beach.
Mark P.
Stayed May 2025
Excellent Cottage
Terrific East end location with easy access to beaches, restaurants, and shore fishing
Lance R.
Stayed Mar 2025
Peace of mindOur Book with Confidence guarantee gives you 24/7 support
All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
More for lessMore space, more privacy, more amenities — more value
Frequently asked questions
Can I find a vacation rental in East End?
Yes, there are vacation rentals in East End close to Sanibel Moorings Botanical Gardens, or you can choose a secluded option if you're looking for extra privacy while you relax.
How many vacation rentals are there in East End?
Choose from 8 Expedia vacation rentals in East End for a memorable vacation.
What's there to see and do in East End?
Sanibel Island Northern Beach and Sanibel Island Southern Beach are a couple of lovely local spots to get outside and enjoy nature. Other places in town to visit include Sanibel Island Lighthouse and Periwinkle Way.
What's a vacation rental in East End like?
A vacation rental is a private property where you can stay for several days or longer in East End. Vacation rentals offer amenities like laundry facilities and kitchens so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can provide a sense of seclusion away from public hotel elevators and busy front desks while still allowing you to travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a family getaway.