Seneca holiday rentals

We found 623 holiday rentals — enter your dates for availability
Select from 210 homes, 27 cottages and other holiday rentals in Seneca to find one that's perfect for your trip. Whether you're travelling with your children or with friends, holiday rentals have the best amenities for spending time at your holiday home, which might include parking and a garden. Whatever you're looking for, you'll find a property to rent to meet everyone's needs, including a place that is accessible or non-smoking.

Holiday rentals with weekly discounts – Seneca

Showing deals for:6 Nov - 13 Nov

Loft bedroom
View from loft
Den
Main floor hallway
Exceptional
(24 reviews)

4-bedroom Chalet 9.4 Miles from Clemson

Six Mile

7% off
S$3,111
for 7 nights, 1 chalet
S$444 per night
includes taxes & fees
4-bedroom Chalet 9.4 Miles from Clemson
Exterior
Living area
view of kitchen from great room.
Refrigerator with dual ice makers, sphere cubes for the perfect cocktail!
Exceptional
(165 reviews)

Clemson Tigers: Open for LSU game due to cancellation 9/5. Price Reduced. DO IT

Six Mile

8% off
S$6,810
for 7 nights, 1 home
S$973 per night
includes taxes & fees
Clemson Tigers: Open for LSU game due to cancellation 9/5. Price Reduced. DO IT
Window view from Sitting Room
Deck
View from the water
Sitting room
Exceptional
(159 reviews)

Pristine views from Lakefront Home

Seneca

7% off
S$5,495
for 7 nights, 1 home
S$785 per night
includes taxes & fees
Pristine views from Lakefront Home
Room
Exterior
Living area
Property grounds
Exceptional
(16 reviews)

Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option

West Union

12% off
S$11,250
for 7 nights, 1 home
S$1,607 per night
includes taxes & fees
Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option
Beverage Fridge
LIVING ROOM
KITCHEN with large countertop for eating and entertaining
View from Kitchen into the Living Room
Exceptional
(13 reviews)

LakeHome On The Water, LUXURY Sleeps 18, Pool, Dock, Beach, Close To Clemson

West Union

9% off
S$17,274
for 7 nights, 1 home
S$2,468 per night
includes taxes & fees
LakeHome On The Water, LUXURY Sleeps 18, Pool, Dock, Beach, Close To Clemson
Interior
Property grounds
Exterior
Room
Exceptional
(9 reviews)

3Mi to Death Valley! 3BR&2BA

Central

12% off
S$2,991
for 7 nights, 1 home
S$427 per night
includes taxes & fees
3Mi to Death Valley! 3BR&2BA
Interior
Exterior
Property grounds
Exterior
Exceptional
(75 reviews)

LUXURY on Lake Keowee. Quiet cove. Putting green. Near Clemson. Sleeps 18

West Union

8% off
S$13,153
for 7 nights, 1 home
S$1,879 per night
includes taxes & fees
LUXURY on Lake Keowee. Quiet cove. Putting green. Near Clemson. Sleeps 18
Queen Guest Room
Upstairs Porch: small portion of porch directly outside living room
Master En Suite
Living Room & Kitchen
Exceptional
(23 reviews)

Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson

Seneca

7% off
S$7,281
for 7 nights, 1 home
S$1,040 per night
includes taxes & fees
Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson
Property grounds
Property grounds
Fully stocked kitchen incl Keurig coffee maker with supplied coffee & air fryer
Exterior
Exceptional
(168 reviews)

Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub

Seneca

8% off
S$4,872
for 7 nights, 1 home
S$696 per night
includes taxes & fees
Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub
Outdoor Dining Seats 8
Sun Room! YES it has A/C
Tiger Den Bedroom
Main Living area
Exceptional
(10 reviews)

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Seneca

8% off
S$5,605
for 7 nights, 1 home
S$801 per night
includes taxes & fees
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Stone walkway to and from lake
Terrace/patio
Dining
Exterior
Exceptional
(41 reviews)

Luxury Lake House on Lake Keowee

Seneca

8% off
S$8,855
for 7 nights, 1 home
S$1,265 per night
includes taxes & fees
Luxury Lake House on Lake Keowee
Interior
Living area
Private kitchen
Interior
Exceptional
(14 reviews)

Lake Keowee Cottage - a high-end luxury rental on the lake

Seneca

8% off
S$12,040
for 7 nights, 1 home
S$1,720 per night
includes taxes & fees
Lake Keowee Cottage - a high-end luxury rental on the lake
Exterior
Interior
Living area
Dining
Exceptional
(6 reviews)

Lake Front Home with Dock "Lake Keowee Retreat"

Seneca

8% off
S$8,069
for 7 nights, 1 home
S$1,153 per night
includes taxes & fees
Lake Front Home with Dock "Lake Keowee Retreat"
backyard
Living area
Living area
Interior
Exceptional
(8 reviews)

Cabaña del Lago

Seneca

8% off
S$6,912
for 7 nights, 1 home
S$987 per night
includes taxes & fees
Cabaña del Lago
Main floor living room
Living area
Living Room/Kitchen
Spacious kitchen with large island
Exceptional
(18 reviews)

Lakefront luxury on Lake Keowee.

Seneca

12% off
S$9,690
for 7 nights, 1 home
S$1,384 per night
includes taxes & fees
Lakefront luxury on Lake Keowee.
Front of house from driveway.
Eat your meals as you enjoy the lakefront scenery.
View of the windows from the loft area.
As you enter, you are greeted with a wall of windows facing he lake.
Exceptional
(220 reviews)

Serenity Bay, Keowee Lakefront Cabin, Covered Dock, Kayaks, Clean, Near Clemson

Seneca

8% off
S$4,548
for 7 nights, 1 home
S$650 per night
includes taxes & fees
Serenity Bay, Keowee Lakefront Cabin, Covered Dock, Kayaks, Clean, Near Clemson
Exterior
Property grounds
Marina
Living area
Exceptional
(56 reviews)

Stoneledge at Lake Keowee Luxury Townhome/Resort Amenities, 12 mi from Clemson

West Union

11% off
S$3,982
for 7 nights, 1 home
S$569 per night
includes taxes & fees
Stoneledge at Lake Keowee Luxury Townhome/Resort Amenities, 12 mi from Clemson
Exterior
Interior
Outdoor dining
Living area
Exceptional
(34 reviews)

Lake Keowee, Waterfront, Dock, Close to Clemson University

Seneca

8% off
S$8,868
for 7 nights, 1 home
S$1,267 per night
includes taxes & fees
Lake Keowee, Waterfront, Dock, Close to Clemson University
Exterior of cabin
Lake view from loft
Bar in kitchen with two barstools
Pool at sunset
Wonderful
(16 reviews)

Lake Keowee! Cozy 2-bedroom cabin in peaceful Six Mile with Pool and Dock Access

Six Mile

8% off
S$1,881
for 7 nights, 1 cabin
S$269 per night
includes taxes & fees
Lake Keowee! Cozy 2-bedroom cabin in peaceful Six Mile with Pool and Dock Access
Great room and kitchen
Steps down to lake
Dining area
Great room and dining
Exceptional
(53 reviews)

Lake Keowee: Lake front 7 mi from Clemson stadium

Seneca

8% off
S$5,400
for 7 nights, 1 home
S$771 per night
includes taxes & fees
Lake Keowee: Lake front 7 mi from Clemson stadium
GORGEOUS sunsets from the jetted jacuzzi tub & there is a beverage fridge too!
Beautiful lake views as you walk up the spiral staircase to main bedroom loft
Chalet is in a gated community w/30 close chalets so please respect neighbors!
Lower level patio has a large table plus an outdoor sectional couch
Exceptional
(42 reviews)

Relax LAKEFRONT: Incredible Panoramic Views & boat slip, 9 Miles to Clemson!

Six Mile

8% off
S$5,180
for 7 nights, 1 home
S$740 per night
includes taxes & fees
Relax LAKEFRONT: Incredible Panoramic Views & boat slip, 9 Miles to Clemson!
Dining
Outdoor dining
Living area
Living area
Exceptional
(34 reviews)

Perfect lake property for Clemson Game Day!

Seneca

16% off
S$5,948
for 7 nights, 1 home
S$850 per night
includes taxes & fees
Perfect lake property for Clemson Game Day!
Fitness facility
Marina
Interior
Interior
Exceptional
(5 reviews)

Welcome to “Tiger Haven” 4 Bed 4 Bath Ultimate Clemson Condo Lake Hartwell

Seneca

17% off
S$6,587
for 7 nights, 1 apartment
S$941 per night
includes taxes & fees
Welcome to “Tiger Haven” 4 Bed 4 Bath Ultimate Clemson Condo Lake Hartwell
Private kitchen
Interior
Room
Exterior
Exceptional
(8 reviews)

Summer Getaway~Experience the Best of the Upstate

Seneca

9% off
S$2,507
for 7 nights, 1 home
S$358 per night
includes taxes & fees
Summer Getaway~Experience the Best of the Upstate
  • Peace of mind

    Our Book with Confidence guarantee gives you 24/7 support
  • More quality time

    From booking to staying, the whole process is simple and enjoyable
  • All the privacy of home

    Enjoy full kitchens, laundry, pools, gardens and more
  • More for less

    More space, more privacy, more amenities — more value

The friendly city of Seneca awaits you

The lake and surrounding scenery provide a peaceful ambience to your holiday home in Seneca. Revered for its sporting events, university setting and boating, this city is both welcoming and scenic. Are you looking for specific amenities for your getaway? Many of our holiday rentals feature full kitchens and laundry facilities.

Activities and attractions in and around Seneca

Are you searching for attractions to visit while you're in town? Venture out of your holiday home and check out everything that makes Seneca a fun spot to go on holiday. These are some of the top attractions to explore, all within 30 miles (48.2 km) of the city centre:

  • Walker Golf Course (6.4 mi / 10.3 km)
  • Keowee Key Golf Course (10.3 mi / 16.5 km)
  • Anderson Motor Speedway (20.9 mi / 33.7 km)
  • Chickasaw Point Golf Club (11.7 mi / 18.8 km)
  • Keowee Springs Golf Course (13.1 mi / 21.1 km)
  • The Rock Golf Course And Resort (24.2 mi / 39 km)

Exploring the natural landscape of Seneca

Whether you're looking for adventure or just want to spend some time taking in the scenery, you'll be sure to find the perfect setting for your holiday in Seneca. These are some of the area's most eye-catching sights, all within 30 miles (48.2 km) of the city centre:

  • Keowee Reservoir (3.7 mi / 6 km)
  • Larry W. Abernathy Waterfront Park (6.6 mi / 10.6 km)
  • South Carolina Botanical Gardens (7.5 mi / 12 km)
  • Lake Keowee (9.3 mi / 14.9 km)
  • Villas at Foxwood Hills (11 mi / 17.7 km)
  • Lake Hartwell State Park (14.1 mi / 22.6 km)

Travelling to and around Seneca

The nearest airport is in Greenville, SC (GSP-Greenville-Spartanburg Intl.), located 44.1 mi (71 km) from the city centre.

Frequently asked questions

What is the best area to stay in Seneca when booking a holiday rental?
Keowee is one of the more popular areas to find a holiday home in Seneca. Browse our relaxing properties and then get ready to discover this destination like a local.
What is the most popular type of holiday rental accommodation in Seneca?
Houses are the most popular kind of holiday rental in Seneca, according to our data. Even if you've got a different vision in mind, Vrbo has properties in all shapes and sizes. Take a look at our options to find your ideal match.
How much does it cost to rent a holiday rental in Seneca?
Several factors can determine how much you pay for a holiday rental in Seneca, such as the length of stay, type of property and season. Still, all Vrbo homes have something in common — exceptional value. Simply enter your travel dates to find your ideal match.
How much does it cost to rent a beach house in Seneca?
The average price for a holiday home by the beach in Seneca will depend on when you're going and the size and style of property you're looking for. You can easily and quickly find prices on Vrbo by entering your travel dates and destination. Then use the handy filters to select the number of bedrooms and amenities that you need, like a pool, WiFi and air conditioning.
Are there pet-friendly holiday rentals in Seneca?
Pack a suitcase and a bone for your canine companion because Seneca has 39 stays that throw open their doors to pets. Let your happy hound enjoy fun with the family at one of our pet-friendly holiday rentals on Vrbo. Simply enter your destination and travel dates, then check our "Pets allowed" filter box.
Can I rent a house with a pool in Seneca?
Check the "pool" box in our filter tool and select from 10 houses with private pools in Seneca on Vrbo. Morning swim, sunset soak or midnight dip? Leisure time is up to you when your holiday property has its own swimming pool.
What are popular rental amenities in Seneca?
When it comes to rental amenities that people look for in Seneca, ski-in/ski-out facilities, a firepit and tennis rank highest. With Vrbo holiday rentals, you'll find options to match your taste and style, whether you're on a trip with friends, relatives or even pets.
Are there large group holiday rentals in Seneca?
With 18 properties that can host 10 people or more in Seneca, there's no need to leave anyone off your guest list. From family get-togethers to special events like anniversary parties and weddings, Vrbo will help you find a large group rental that fits the occasion.
Are there holiday rentals in Seneca that welcome kids?
Seneca has 39 family-friendly holiday homes. And booking a stay that welcomes children is a cinch with Vrbo's "Properties good for families" filter. As well as having the whole place to yourselves, you'll also get access to perks and conveniences such as living rooms, private pools and yards.
Are there one-bedroom holiday rentals in Seneca?
Seneca has four one-bedroom rentals on offer. Usually situated in popular areas because of their compact size, a one-bedroom holiday rental is ideal if you're travelling with your partner or a friend. And with comforts such as wireless internet and more privacy than a standard hotel, you'll be able to kick back while discovering this fantastic destination.
Are there holiday rentals with WiFi in Seneca?
You'll have a choice of 22 holiday rentals with WiFi in Seneca. If you'd like to disconnect from daily life during your trip, but still want to be connected to the internet, these properties have what you need. Narrow your search by applying the WiFi filter on Vrbo.
How can I find holiday rentals with air conditioning in Seneca?
You can choose from 39 Vrbo holiday homes with air conditioning in Seneca giving you that cooling breeze and extra level of comfort. Simply enter your preferred dates of travel and then take advantage of our filter tool to help you locate properties with air conditioning.
How old do you have to be to rent a holiday rental in Seneca?
The age limit can vary across properties on Vrbo, so be sure to check the rules of the holiday home in Seneca you want. But usually, it's 16, 18 or 21.
How long can I rent a holiday rental in Seneca for?
It's really down to the Seneca property. To see a list of options offering extended stays, just enter your dates and number of people into Vrbo's search page. Look forward to having the property to yourself, as well as comforts such as a fully-equipped kitchen, air conditioning and a backyard where the kids can run around and play. Keep your eyes peeled for any long-term stays that offer weekly or monthly discounts.

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