Seneca holiday rentals

We found 625 holiday rentals — enter your dates for availability
Select from 210 homes, 27 cottages and other holiday rentals in Seneca to find one that's perfect for your trip. Whether you're travelling with your children or with friends, holiday rentals have the best amenities for spending time at your holiday home, which might include parking and a garden. Whatever you're looking for, you'll find a property to rent to meet everyone's needs, including a place that is accessible or non-smoking.

Holiday rentals with weekly discounts – Seneca

Showing deals for:6 Nov - 13 Nov

Main floor hallway
View from loft
Den
View from main deck
Exceptional
(24 reviews)

4-bedroom Chalet 9.4 Miles from Clemson

Six Mile

7% off
S$3,119
for 7 nights, 1 chalet
S$446 per night
includes taxes & fees
4-bedroom Chalet 9.4 Miles from Clemson
Exterior
Living area
Deck room from main deck
Refrigerator with dual ice makers, sphere cubes for the perfect cocktail!
Exceptional
(165 reviews)

Clemson Tigers: Open for LSU game due to cancellation 9/5. Price Reduced. DO IT

Six Mile

8% off
S$6,826
for 7 nights, 1 home
S$975 per night
includes taxes & fees
Clemson Tigers: Open for LSU game due to cancellation 9/5. Price Reduced. DO IT
View towards house from dock
Deck
View from the water
Window view from Sitting Room
Exceptional
(159 reviews)

Pristine views from Lakefront Home

Seneca

7% off
S$5,508
for 7 nights, 1 home
S$787 per night
includes taxes & fees
Pristine views from Lakefront Home
Exterior
Property grounds
Interior
Private kitchen
Exceptional
(42 reviews)

Lake Keowee waterfront Escape!

West Union

8% off
S$18,009
for 7 nights, 1 home
S$2,573 per night
includes taxes & fees
Lake Keowee waterfront Escape!
Room
Exterior
Property grounds
Interior
Exceptional
(16 reviews)

Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option

West Union

12% off
S$11,261
for 7 nights, 1 home
S$1,609 per night
includes taxes & fees
Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option
KITCHEN with large countertop for eating and entertaining
LIVING ROOM
View from Kitchen into the Living Room
FRONT DOOR
Exceptional
(13 reviews)

LakeHome On The Water, LUXURY Sleeps 18, Pool, Dock, Beach, Close To Clemson

West Union

9% off
S$17,315
for 7 nights, 1 home
S$2,474 per night
includes taxes & fees
LakeHome On The Water, LUXURY Sleeps 18, Pool, Dock, Beach, Close To Clemson
Private kitchen
Property grounds
Exterior
Interior
Exceptional
(9 reviews)

3Mi to Death Valley! 3BR&2BA

Central

12% off
S$2,998
for 7 nights, 1 home
S$428 per night
includes taxes & fees
3Mi to Death Valley! 3BR&2BA
Private kitchen
Exterior
Property grounds
Exterior
Exceptional
(75 reviews)

LUXURY on Lake Keowee. Quiet cove. Putting green. Near Clemson. Sleeps 18

West Union

8% off
S$13,184
for 7 nights, 1 home
S$1,883 per night
includes taxes & fees
LUXURY on Lake Keowee. Quiet cove. Putting green. Near Clemson. Sleeps 18
Living Room & Kitchen
Upstairs Porch: small portion of porch directly outside living room
Queen Guest Room
Master En Suite
Exceptional
(23 reviews)

Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson

Seneca

7% off
S$7,298
for 7 nights, 1 home
S$1,043 per night
includes taxes & fees
Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson
Living area
Dining
Keowee has beautiful clean water. Safe for swimming, & the fish are safe to eat!
Exterior
Exceptional
(78 reviews)

Keowee Lakefront dock, canoe, kayaks, and more!

Seneca

16% off
S$7,803
for 7 nights, 1 home
S$1,115 per night
includes taxes & fees
Keowee Lakefront dock, canoe, kayaks, and more!
65 inch TV with You Tube TV.  Gas fire place.
Property grounds
Fully stocked kitchen incl Keurig coffee maker with supplied coffee & air fryer
Exterior
Exceptional
(168 reviews)

Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub

Seneca

8% off
S$4,883
for 7 nights, 1 home
S$698 per night
includes taxes & fees
Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub
Stone walkway to and from lake
Terrace/patio
Pool
Dining
Exceptional
(41 reviews)

Luxury Lake House on Lake Keowee

Seneca

8% off
S$8,876
for 7 nights, 1 home
S$1,268 per night
includes taxes & fees
Luxury Lake House on Lake Keowee
Tiger Den Bedroom
Sun Room! YES it has A/C
Outdoor Dining Seats 8
Main Living area
Exceptional
(10 reviews)

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Seneca

8% off
S$5,632
for 7 nights, 1 home
S$805 per night
includes taxes & fees
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Interior
Living area
Private kitchen
Exterior
Exceptional
(14 reviews)

Lake Keowee Cottage - a high-end luxury rental on the lake

Seneca

8% off
S$12,068
for 7 nights, 1 home
S$1,724 per night
includes taxes & fees
Lake Keowee Cottage - a high-end luxury rental on the lake
Firepit and Deck
Exterior
Living room
Dining seating for 14
Exceptional
(43 reviews)

Clemson Hartwell Lake House, 5 kings, Football weekends open now, book early!

Seneca

7% off
S$5,916
for 7 nights, 1 home
S$845 per night
includes taxes & fees
Clemson Hartwell Lake House, 5 kings, Football weekends open now, book early!
Living area
Interior
Living area
Dining
Exceptional
(6 reviews)

Lake Front Home with Dock "Lake Keowee Retreat"

Seneca

8% off
S$8,088
for 7 nights, 1 home
S$1,155 per night
includes taxes & fees
Lake Front Home with Dock "Lake Keowee Retreat"
Interior
Living area
Living area
backyard
Exceptional
(8 reviews)

Cabaña del Lago

Seneca

8% off
S$6,922
for 7 nights, 1 home
S$989 per night
includes taxes & fees
Cabaña del Lago
Living Room/Kitchen
Living area
Spacious kitchen with large island
Main floor living room
Exceptional
(18 reviews)

Lakefront luxury on Lake Keowee.

Seneca

12% off
S$9,712
for 7 nights, 1 home
S$1,387 per night
includes taxes & fees
Lakefront luxury on Lake Keowee.
Interior
Beautiful Large House with lots of room for up to 10 Guests.
Private kitchen
Dining
Excellent
(50 reviews)

Enjoy!!! Beautiful, Seasonal Views of Lake Hartwell with Private Community Dock

Fair Play

14% off
S$3,001
for 7 nights, 1 home
S$429 per night
includes taxes & fees
Enjoy!!! Beautiful, Seasonal Views of Lake Hartwell with Private Community Dock
Exterior
Eat your meals as you enjoy the lakefront scenery.
Front of house from driveway.
As you enter, you are greeted with a wall of windows facing he lake.
Exceptional
(220 reviews)

Serenity Bay, Keowee Lakefront Cabin, Covered Dock, Kayaks, Clean, Near Clemson

Seneca

8% off
S$4,559
for 7 nights, 1 home
S$651 per night
includes taxes & fees
Serenity Bay, Keowee Lakefront Cabin, Covered Dock, Kayaks, Clean, Near Clemson
Marina
Property grounds
Exterior
Living area
Exceptional
(56 reviews)

Stoneledge at Lake Keowee Luxury Townhome/Resort Amenities, 12 mi from Clemson

West Union

11% off
S$3,992
for 7 nights, 1 home
S$570 per night
includes taxes & fees
Stoneledge at Lake Keowee Luxury Townhome/Resort Amenities, 12 mi from Clemson
Private kitchen
Interior
Outdoor dining
Living area
Exceptional
(34 reviews)

Lake Keowee, Waterfront, Dock, Close to Clemson University

Seneca

8% off
S$8,889
for 7 nights, 1 home
S$1,270 per night
includes taxes & fees
Lake Keowee, Waterfront, Dock, Close to Clemson University
Bar in kitchen with two barstools
Lake view from loft
Large windows on backside of cabin
Exterior of cabin
Wonderful
(16 reviews)

Lake Keowee! Cozy 2-bedroom cabin in peaceful Six Mile with Pool and Dock Access

Six Mile

8% off
S$1,885
for 7 nights, 1 cabin
S$269 per night
includes taxes & fees
Lake Keowee! Cozy 2-bedroom cabin in peaceful Six Mile with Pool and Dock Access
Master bedroom main level
Steps down to lake
Dining area
Great room and kitchen
Exceptional
(53 reviews)

Lake Keowee: Lake front 7 mi from Clemson stadium

Seneca

8% off
S$5,412
for 7 nights, 1 home
S$773 per night
includes taxes & fees
Lake Keowee: Lake front 7 mi from Clemson stadium
  • Peace of mind

    Our Book with Confidence guarantee gives you 24/7 support
  • More quality time

    From booking to staying, the whole process is simple and enjoyable
  • All the privacy of home

    Enjoy full kitchens, laundry, pools, gardens and more
  • More for less

    More space, more privacy, more amenities — more value

The friendly city of Seneca awaits you

The lake and surrounding scenery provide a peaceful ambience to your holiday home in Seneca. Revered for its sporting events, university setting and boating, this city is both welcoming and scenic. Are you looking for specific amenities for your getaway? Many of our holiday rentals feature full kitchens and laundry facilities.

Activities and attractions in and around Seneca

Are you searching for attractions to visit while you're in town? Venture out of your holiday home and check out everything that makes Seneca a fun spot to go on holiday. These are some of the top attractions to explore, all within 30 miles (48.2 km) of the city centre:

  • Walker Golf Course (6.4 mi / 10.3 km)
  • Keowee Key Golf Course (10.3 mi / 16.5 km)
  • Chickasaw Point Golf Club (11.7 mi / 18.8 km)
  • Anderson Motor Speedway (20.9 mi / 33.7 km)
  • Cateechee Golf Club (25.2 mi / 40.5 km)
  • Keowee Springs Golf Course (13.1 mi / 21.1 km)

Exploring the natural landscape of Seneca

Whether you're looking for adventure or just want to spend some time taking in the scenery, you'll be sure to find the perfect setting for your holiday in Seneca. These are some of the area's most eye-catching sights, all within 30 miles (48.2 km) of the city centre:

  • Keowee Reservoir (3.7 mi / 6 km)
  • South Carolina Botanical Gardens (7.5 mi / 12 km)
  • Lake Keowee (9.3 mi / 14.9 km)
  • Lake Hartwell State Park (14.1 mi / 22.6 km)
  • Lake Hartwell (15.5 mi / 25 km)
  • Whitewater Lake (15.7 mi / 25.2 km)

Travelling to and around Seneca

The nearest airport is in Greenville, SC (GSP-Greenville-Spartanburg Intl.), located 44.1 mi (71 km) from the city centre.

Frequently asked questions

What is the best area to stay in Seneca when booking a holiday rental?
Keowee is one of the more popular areas to find a holiday home in Seneca. Browse our relaxing properties and then get ready to discover this destination like a local.
What is the most popular type of holiday rental accommodation in Seneca?
Houses are the most popular kind of holiday rental in Seneca, according to our data. Even if you've got a different vision in mind, Vrbo has properties in all shapes and sizes. Take a look at our options to find your ideal match.
How much does it cost to rent a holiday rental in Seneca?
Several factors can determine how much you pay for a holiday rental in Seneca, such as the length of stay, type of property and season. Still, all Vrbo homes have something in common — exceptional value. Simply enter your travel dates to find your ideal match.
How much does it cost to rent a beach house in Seneca?
The average price for a holiday home by the beach in Seneca will depend on when you're going and the size and style of property you're looking for. You can easily and quickly find prices on Vrbo by entering your travel dates and destination. Then use the handy filters to select the number of bedrooms and amenities that you need, like a pool, WiFi and air conditioning.
Are there pet-friendly holiday rentals in Seneca?
Pack a suitcase and a bone for your canine companion because Seneca has 39 stays that throw open their doors to pets. Let your happy hound enjoy fun with the family at one of our pet-friendly holiday rentals on Vrbo. Simply enter your destination and travel dates, then check our "Pets allowed" filter box.
Can I rent a house with a pool in Seneca?
Check the "pool" box in our filter tool and select from 10 houses with private pools in Seneca on Vrbo. Morning swim, sunset soak or midnight dip? Leisure time is up to you when your holiday property has its own swimming pool.
What are popular rental amenities in Seneca?
When it comes to rental amenities that people look for in Seneca, ski-in/ski-out facilities, a firepit and tennis rank highest. With Vrbo holiday rentals, you'll find options to match your taste and style, whether you're on a trip with friends, relatives or even pets.
Are there large group holiday rentals in Seneca?
With 18 properties that can host 10 people or more in Seneca, there's no need to leave anyone off your guest list. From family get-togethers to special events like anniversary parties and weddings, Vrbo will help you find a large group rental that fits the occasion.
Are there holiday rentals in Seneca that welcome kids?
Seneca has 39 family-friendly holiday homes. And booking a stay that welcomes children is a cinch with Vrbo's "Properties good for families" filter. As well as having the whole place to yourselves, you'll also get access to perks and conveniences such as living rooms, private pools and yards.
Are there one-bedroom holiday rentals in Seneca?
Seneca has four one-bedroom rentals on offer. Usually situated in popular areas because of their compact size, a one-bedroom holiday rental is ideal if you're travelling with your partner or a friend. And with comforts such as wireless internet and more privacy than a standard hotel, you'll be able to kick back while discovering this fantastic destination.
Are there holiday rentals with WiFi in Seneca?
You'll have a choice of 22 holiday rentals with WiFi in Seneca. If you'd like to disconnect from daily life during your trip, but still want to be connected to the internet, these properties have what you need. Narrow your search by applying the WiFi filter on Vrbo.
How can I find holiday rentals with air conditioning in Seneca?
You can choose from 39 Vrbo holiday homes with air conditioning in Seneca giving you that cooling breeze and extra level of comfort. Simply enter your preferred dates of travel and then take advantage of our filter tool to help you locate properties with air conditioning.
How old do you have to be to rent a holiday rental in Seneca?
The age limit can vary across properties on Vrbo, so be sure to check the rules of the holiday home in Seneca you want. But usually, it's 16, 18 or 21.
How long can I rent a holiday rental in Seneca for?
It's really down to the Seneca property. To see a list of options offering extended stays, just enter your dates and number of people into Vrbo's search page. Look forward to having the property to yourself, as well as comforts such as a fully-equipped kitchen, air conditioning and a backyard where the kids can run around and play. Keep your eyes peeled for any long-term stays that offer weekly or monthly discounts.

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