Photo by Cindy Keese

Seneca villas

We found 7 villas — enter your dates for availability

  • Peace of mind

    Our Book with Confidence guarantee gives you 24/7 support
  • More quality time

    From booking to staying, the whole process is simple and enjoyable
  • All the privacy of home

    Enjoy full kitchens, laundry, pools, gardens and more
  • More for less

    More space, more privacy, more amenities — more value

Frequently asked questions

How much does it cost to stay in a villa rental in Seneca?
Prices vary according to the time of year, length of stay and exact property location, so key in your trip details to discover what's available. No matter your budget or plans, Vrbo has villa rentals in Seneca for guests of all types.
When is the best time to rent a villa in Seneca?
Consider escaping to Seneca in June, when the average daily temperature ranges between 18 ºC (64 ºF) and 31 ºC (88 ºF). This is the most popular time of year for Vrbo guests to stay in a villa rental in this destination, which is located in Oconee County.
Where can I rent a Seneca villa with great views?
If you'd like your trip to feature views of historic areas, Vrbo has some villa rentals in Seneca that are right up your alley. Browse for a villa with vistas by using our handy "Highly rated for location" filter under "Property reviews" and check out the available options.
Can I book a luxury villa in Seneca?
Take your trip to the next level when you book one of our villa rentals in Seneca. Offering premium conveniences such as fully-equipped kitchens, in-home technology features and quality furnishings, you and your guests will feel like VIPs. Use our filter tool to find properties with high-class perks like hot tubs and pools for that extra layer of opulence and luxury.
What are the top things to do in Seneca?
One of the first things to do after finding your villa rental is to pack your itinerary with fun activities and sights. There's lots of them in Seneca, with some of the best family-friendly attractions including Lake Keowee, Memorial Stadium and South Carolina Botanical Gardens.
Why should I book my villa holiday with Vrbo?
With customer support always available, peace of mind is guaranteed when you book through Vrbo. As soon as you lock in your villa rental to even after your holiday is over, we'll be by your side every step of the way. It's all part of our Book with Confidence Guarantee. What's more, we also have a secure and easy payment process and flexible cancellation policies