Discover a selection of 39 vacation rentals in Santa Isabel, PR that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and private pools. Prices start at $60 per night, and condos and houses are popular options for a stay in Santa Isabel. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — Santa Isabel
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How many vacation rentals are available around Santa Isabel, PR?

Our 2022 property listings offer a large selection of 39 vacation rentals around Santa Isabel. From 10 condo and apartment rentals to 13 house rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What are the most popular destinations to visit in Santa Isabel?

There are many lovely places to stay for a holiday trip or just for a weekend in Santa Isabel. From Vrbo travelers, the top most popular destinations to visit are:

  • Jauca I: 16 vacation rentals
  • Jauca II: 26 vacation rentals
  • Felicia II: 16 vacation rentals
  • Playa: 16 vacation rentals
  • Descalabrado: 27 vacation rentals

And Vrbo offers you the chance to discover many other popular destinations in Santa Isabel! Please use our search bar to access the selection of vacation rentals available in other popular destinations.