The nearest airport is in Fiumicino - Leonardo da Vinci Intl. Airport (FCO), located 5.7 mi (9.1 km) from the city center. If you can't find a flight that's convenient for your trip, you could book a flight to Ciampino Airport (CIA), which is 15.8 mi (25.5 km) away.
If you prefer train travel, the main station is Rome Castel Fusano Station.