San Diego Santa Fe Depot vacation rentals
We found 7,133 vacation rentals — enter your dates for availability
Discover a selection of private vacation rentals close to San Diego Santa Fe Depot that can be your home away from home. Whether you're going on vacation with family or friends, vacation rentals have the best amenities for hanging out with the people that matter most, which might include parking and a pool. You'll be sure to find a rental that has what everyone needs, including options that are accessible or non-smoking.
Vacation rentals with weekly discounts - San Diego Santa Fe Depot
Showing deals for:Nov 7 - Nov 14
Image gallery for Beautiful Normal Heights Living
1010 out of 10 rating
Exceptional
(55 reviews)
Beautiful Normal Heights Living
San Diego, CA
12% off
Price is CA $301
CA $301
CA $2,605 total
CA $2,605 total
includes taxes & fees
Image gallery for La Jolla Shores Remodel w/ Balcony, 2 Units in 1 & Steps from the Beach!
1010 out of 10 rating
Exceptional
(24 reviews)
La Jolla Shores Remodel w/ Balcony, 2 Units in 1 & Steps from the Beach!
La Jolla, CA
5% off
Price is CA $478
CA $478
CA $4,540 total
CA $4,540 total
includes taxes & fees
Image gallery for 3 bedroom Central Escape - Hot Tub, Fire Pit & newly renovated sunny back yard
1010 out of 10 rating
Exceptional
(7 reviews)
3 bedroom Central Escape - Hot Tub, Fire Pit & newly renovated sunny back yard
San Diego, CA
10% off
Price is CA $449
CA $449
CA $4,206 total
CA $4,206 total
includes taxes & fees
Image gallery for Panoramic Ocean Views, Private Heated Pool, Spa, and Waterslide!
9.89.8 out of 10 rating
Exceptional
(126 reviews)
Panoramic Ocean Views, Private Heated Pool, Spa, and Waterslide!
San Diego, CA
10% off
Price is CA $1,317
CA $1,317
CA $11,611 total
CA $11,611 total
includes taxes & fees
Image gallery for Zen Hilltop Resort: Heated Infinity Pool, Spa, 360° SoCal Views
1010 out of 10 rating
Exceptional
(13 reviews)
Zen Hilltop Resort: Heated Infinity Pool, Spa, 360° SoCal Views
El Cajon, CA
10% off
Price is CA $998
CA $998
CA $8,577 total
CA $8,577 total
includes taxes & fees
Image gallery for Central, Family-Friendly, Clean San Diego 3bed/2bath home w/backyard
9.89.8 out of 10 rating
Exceptional
(10 reviews)
Central, Family-Friendly, Clean San Diego 3bed/2bath home w/backyard
San Diego, CA
10% off
Price is CA $339
CA $339
CA $3,269 total
CA $3,269 total
includes taxes & fees
Image gallery for Canyon View Tranquil Oasis w/ Private Pool and Dreamy Sunsets, New Backyard
9.49.4 out of 10 rating
Exceptional
(53 reviews)
Canyon View Tranquil Oasis w/ Private Pool and Dreamy Sunsets, New Backyard
San Diego, CA
10% off
Price is CA $296
CA $296
CA $3,132 total
CA $3,132 total
includes taxes & fees
Image gallery for Ocean Front * 2 Levels * 2 Water View Patios * AC
1010 out of 10 rating
Exceptional
(15 reviews)
Ocean Front * 2 Levels * 2 Water View Patios * AC
San Diego, CA
10% off
Price is CA $811
CA $811
CA $8,440 total
CA $8,440 total
includes taxes & fees
Image gallery for Spacious Ocean Beach Studio w/ Parking - Short Walk to the Beach
9.29.2 out of 10 rating
Wonderful
(12 reviews)
Spacious Ocean Beach Studio w/ Parking - Short Walk to the Beach
San Diego, CA
10% off
Price is CA $246
CA $246
CA $2,272 total
CA $2,272 total
includes taxes & fees
Image gallery for Large space 4 large groups, families, intimate celebrations, retreats & reunion.
9.89.8 out of 10 rating
Exceptional
(34 reviews)
Large space 4 large groups, families, intimate celebrations, retreats & reunion.
Chula Vista, CA
10% off
Price is CA $454
CA $454
CA $4,468 total
CA $4,468 total
includes taxes & fees
Image gallery for Centrally located in San Diego, AC, walkable to Hillcrest,near downtown-beaches!
9.29.2 out of 10 rating
Wonderful
(5 reviews)
Centrally located in San Diego, AC, walkable to Hillcrest,near downtown-beaches!
San Diego, CA
10% off
Price is CA $493
CA $493
CA $4,868 total
CA $4,868 total
includes taxes & fees
Image gallery for Quiet 3 Bedroom Family Home Close to All
1010 out of 10 rating
Exceptional
(75 reviews)
Quiet 3 Bedroom Family Home Close to All
San Diego, CA
10% off
Price is CA $437
CA $437
CA $4,171 total
CA $4,171 total
includes taxes & fees
Image gallery for Del Mar Beaches~Luxury Ocean View Townhouse!
9.49.4 out of 10 rating
Exceptional
(101 reviews)
Del Mar Beaches~Luxury Ocean View Townhouse!
Del Mar, CA
10% off
Price is CA $456
CA $456
CA $4,503 total
CA $4,503 total
includes taxes & fees
Image gallery for 2-Bedroom Coastal Gem, Just Steps to the Sand
8.08.0 out of 10 rating
Very good
(11 reviews)
2-Bedroom Coastal Gem, Just Steps to the Sand
San Diego, CA
10% off
Price is CA $501
CA $501
CA $4,506 total
CA $4,506 total
includes taxes & fees
Image gallery for 5BR | Luxury Home | Salt Water Pool | Hot Tub | Fire Pit
9.89.8 out of 10 rating
Exceptional
(14 reviews)
5BR | Luxury Home | Salt Water Pool | Hot Tub | Fire Pit
San Diego, CA
15% off
Price is CA $730
CA $730
CA $6,823 total
CA $6,823 total
includes taxes & fees
Image gallery for Beautiful 2 bed 2 bath one block from Mission Bay!
9.29.2 out of 10 rating
Wonderful
(25 reviews)
Beautiful 2 bed 2 bath one block from Mission Bay!
San Diego, CA
10% off
Price is CA $180
CA $180
CA $1,826 total
CA $1,826 total
includes taxes & fees
Image gallery for Blue Heron Beach House - Near the Beach with a backyard and bikes!
1010 out of 10 rating
Exceptional
(43 reviews)
Blue Heron Beach House - Near the Beach with a backyard and bikes!
San Diego, CA
10% off
Price is CA $476
CA $476
CA $4,753 total
CA $4,753 total
includes taxes & fees
Image gallery for Beach Vibes
1010 out of 10 rating
Exceptional
(14 reviews)
Beach Vibes
Spring Valley, CA
10% off
Price is CA $212
CA $212
CA $1,974 total
CA $1,974 total
includes taxes & fees
Image gallery for Spacious South Park Gem | Heated Pool + Charm
9.89.8 out of 10 rating
Exceptional
(9 reviews)
Spacious South Park Gem | Heated Pool + Charm
San Diego, CA
5% off
Price is CA $1,242
CA $1,242
CA $11,156 total
CA $11,156 total
includes taxes & fees
Image gallery for Entire Building! 4 Units + 2 Levels + 4 Patios + 8 Parking
1010 out of 10 rating
Exceptional
(5 reviews)
Entire Building! 4 Units + 2 Levels + 4 Patios + 8 Parking
San Diego, CA
10% off
Price is CA $1,585
CA $1,585
CA $15,909 total
CA $15,909 total
includes taxes & fees
Image gallery for Ocean Front! Exclusive Beachfront Patio + A/C
9.09.0 out of 10 rating
Wonderful
(16 reviews)
Ocean Front! Exclusive Beachfront Patio + A/C
San Diego, CA
10% off
Price is CA $460
CA $460
CA $4,881 total
CA $4,881 total
includes taxes & fees
Image gallery for On the Sand! | Single-Family Oceanfront Home | AC + Sunset Views
1010 out of 10 rating
Exceptional
(19 reviews)
On the Sand! | Single-Family Oceanfront Home | AC + Sunset Views
San Diego, CA
15% off
Price is CA $1,138
CA $1,138
CA $11,264 total
CA $11,264 total
includes taxes & fees
Image gallery for Amazing Resort Condo w/ tennis courts, pool, & hot tubs — 5 min from the beach!
1010 out of 10 rating
Exceptional
(5 reviews)
Amazing Resort Condo w/ tennis courts, pool, & hot tubs — 5 min from the beach!
Solana Beach, CA
15% off
Price is CA $351
CA $351
CA $2,834 total
CA $2,834 total
includes taxes & fees
Image gallery for Luxury home with beautiful views - 15 min from DT!
1010 out of 10 rating
Exceptional
(11 reviews)
Luxury home with beautiful views - 15 min from DT!
San Diego, CA
10% off
Price is CA $563
CA $563
CA $5,095 total
CA $5,095 total
includes taxes & fees
Find spaces that suit your style
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Find the best place to stay - San Diego Santa Fe Depot
Little Italy Inn - Limited Service Apart Hotel
Sleeps 2 · 1 bedroom
7.87.8 out of 10
Goodgood
34 reviews(34 reviews)
Charming 2-bedroom cottage in San Diego with AC, WiFi
Sleeps 6 · 2 bedrooms · 1 bathroom
9.49.4 out of 10
Exceptionalexceptional
3 reviews(3 reviews)
Beautiful bedroom with private bathroom in charming Coronado.
Sleeps 1 · 1 bedroom · 1 bathroom
1010 out of 10
Exceptionalexceptional
1 review(1 review)
Charming 1-bedroom, 20 mins to Airport, Beaches, Gaslamp
Sleeps 3 · 1 bedroom · 1 bathroom
1010 out of 10
Exceptionalexceptional
Famous Ocean Beach, Walk To Everything
Sleeps 3 · 1 bedroom · 1 bathroom
9.09.0 out of 10
Wonderfulwonderful
8 reviews(8 reviews)
Mission Bay Beach Cottage
Sleeps 4 · 1 bedroom · 1 bathroom
9.69.6 out of 10
Exceptionalexceptional
29 reviews(29 reviews)
Top rated rentals - San Diego Santa Fe Depot
Fabulous...simply fabulous!
1010 out of 10
Exceptionalexceptional
171 reviews(171 reviews)
A stunning property with an equally stunning view.
Even though we arrived later than planned, our host was there to welcome us, walk us through the house and answer all our questions.
Facilities were good...everything you'd need to look after a family for several days was in place.
Would definitely stay again!
Gillian B M.
Stayed Oct 2024
Fabulous Getaway
1010 out of 10
Exceptionalexceptional
209 reviews(209 reviews)
There were 8 of us and we all enjoyed our stay at the Seagirt Retreat! Steps away from the beach with great views from the balconies while enjoying our morning coffee.
Would absolutely return to this fabulous home away from home.
Gary S.
Stayed Sep 2024
Great place to stay and see San Diego
1010 out of 10
Exceptionalexceptional
239 reviews(239 reviews)
I visited this home with my extended family. The house was incredible, had lots of space and was very comfortable. Scott was very accommodating and very responsive to our needs and we hope to visit once again.
David J.
Stayed Mar 2024
Great host's and location.
1010 out of 10
Exceptionalexceptional
171 reviews(171 reviews)
Elizabeth and Tim were amazing host's.Enjoyed our stay and excellent location.
John H.
Stayed Feb 2024
Great home away from home
1010 out of 10
Exceptionalexceptional
16 reviews(16 reviews)
Lovely condo in an excellent location.
Raymond W.
Stayed Nov 2023
Peace of mindOur Book with Confidence guarantee gives you 24/7 support
More quality timeFrom booking to staying, the whole process is simple and enjoyable
All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
More for lessMore space, more privacy, more amenities — more value