Vacation rentals near James S. McDonnell Prologue Room
We found 1,392 vacation rentals — enter your dates for availability
If you want to to stay within easy reach of James S. McDonnell Prologue Room, take a look at vacation rentals to find the perfect home base for your trip. Whether you’re staying in a vacation home with a group or just with your pet, you'll have the best amenities for spending time at your home away from home, such as air conditioning and a TV. Whatever you're looking for, you'll find a rental to meet everyone's needs, including accessible or non-smoking choices.
Vacation rentals with weekly discounts - James S. McDonnell Prologue Room
Showing deals for:Nov 14 - Nov 21
Image gallery for The Blue House near Frank Holten State Park / Golf /Lighthouse Restaurant
9.49.4 out of 10 rating
Exceptional
(8 reviews)
The Blue House near Frank Holten State Park / Golf /Lighthouse Restaurant
East St. Louis, IL
15% off
Price is CA $146
CA $146
CA $1,397 total
CA $1,397 total
includes taxes & fees
Image gallery for Cozy vacation home just 20 minutes from Six Flags St. Louis
8.48.4 out of 10 rating
Very good
(45 reviews)
Cozy vacation home just 20 minutes from Six Flags St. Louis
Ballwin, MO
10% off
Price is CA $194
CA $194
CA $1,775 total
CA $1,775 total
includes taxes & fees
Image gallery for Elegant house pool, sports, pizza & boat bar, business center, mini theater.
9.09.0 out of 10 rating
Wonderful
(18 reviews)
Elegant house pool, sports, pizza & boat bar, business center, mini theater.
St. Louis, MO
10% off
Price is CA $529
CA $529
CA $4,200 total
CA $4,200 total
includes taxes & fees
Image gallery for Grafton Escape #1 - River views! Pool! Walking distance to bars/restaurants
9.69.6 out of 10 rating
Exceptional
(65 reviews)
Grafton Escape #1 - River views! Pool! Walking distance to bars/restaurants
Grafton, IL
10% off
Price is CA $168
CA $168
CA $1,501 total
CA $1,501 total
includes taxes & fees
Image gallery for Charming Escape in Grafton!
1010 out of 10 rating
Exceptional
(9 reviews)
Charming Escape in Grafton!
Grafton, IL
10% off
Price is CA $255
CA $255
CA $2,267 total
CA $2,267 total
includes taxes & fees
Image gallery for Guest House 632 Summit Street
1010 out of 10 rating
Exceptional
(187 reviews)
Guest House 632 Summit Street
Alton, IL
10% off
Price is CA $204
CA $204
CA $1,745 total
CA $1,745 total
includes taxes & fees
Image gallery for Perfect Weekend Getaway! Condo With Great River Views! Pool!
9.89.8 out of 10 rating
Exceptional
(134 reviews)
Perfect Weekend Getaway! Condo With Great River Views! Pool!
Grafton, IL
10% off
Price is CA $205
CA $205
CA $1,674 total
CA $1,674 total
includes taxes & fees
Image gallery for Beautifull *4BDR/ 2Bath *Home Close to Parks and Downtown!
9.89.8 out of 10 rating
Exceptional
(20 reviews)
Beautifull *4BDR/ 2Bath *Home Close to Parks and Downtown!
St. Louis, MO
10% off
Price is CA $199
CA $199
CA $1,757 total
CA $1,757 total
includes taxes & fees
Image gallery for The River Stables in St. Charles, MO
9.69.6 out of 10 rating
Exceptional
(10 reviews)
The River Stables in St. Charles, MO
St. Charles, MO
20% off
Price is CA $276
CA $276
CA $2,769 total
CA $2,769 total
includes taxes & fees
Image gallery for 5-bedroom vacation home in Soulard
9.69.6 out of 10 rating
Exceptional
(5 reviews)
5-bedroom vacation home in Soulard
St. Louis, MO
5% off
Price is CA $729
CA $729
CA $6,298 total
CA $6,298 total
includes taxes & fees
Image gallery for Beautiful 4-bedroom house Central to St. Louis and St. Charles
8.08.0 out of 10 rating
Very good
(9 reviews)
Beautiful 4-bedroom house Central to St. Louis and St. Charles
Overland, MO
10% off
Price is CA $202
CA $202
CA $1,730 total
CA $1,730 total
includes taxes & fees
Image gallery for Riverside Home - Modern meets comfort
1010 out of 10 rating
Exceptional
(52 reviews)
Riverside Home - Modern meets comfort
Grafton, IL
10% off
Price is CA $263
CA $263
CA $2,372 total
CA $2,372 total
includes taxes & fees
Image gallery for Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
1010 out of 10 rating
Exceptional
(34 reviews)
Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
St. Charles, MO
5% off
Price is CA $141
CA $141
CA $1,487 total
CA $1,487 total
includes taxes & fees
Image gallery for Grafton Getaway-Riverhouse....a waterfront property with bike trail in backyard
1010 out of 10 rating
Exceptional
(68 reviews)
Grafton Getaway-Riverhouse....a waterfront property with bike trail in backyard
Grafton, IL
11% off
Price is CA $357
CA $357
CA $2,998 total
CA $2,998 total
includes taxes & fees
Image gallery for Escape the city to quiet and picturesque Golden Eagle, IL..
1010 out of 10 rating
Exceptional
(353 reviews)
Escape the city to quiet and picturesque Golden Eagle, IL..
Golden Eagle, IL
10% off
Price is CA $241
CA $241
CA $2,160 total
CA $2,160 total
includes taxes & fees
Image gallery for Stylish South City King 1BR Apt
1010 out of 10 rating
Exceptional
(6 reviews)
Stylish South City King 1BR Apt
St. Louis, MO
10% off
Price is CA $150
CA $150
CA $1,427 total
CA $1,427 total
includes taxes & fees
Image gallery for Casa de Saint Charles
9.29.2 out of 10 rating
Wonderful
(14 reviews)
Casa de Saint Charles
St. Charles, MO
5% off
Price is CA $674
CA $674
CA $5,412 total
CA $5,412 total
includes taxes & fees
Image gallery for Perfect Getaway 3BR/3BA Entire Home with Free Parking
1010 out of 10 rating
Exceptional
(18 reviews)
Perfect Getaway 3BR/3BA Entire Home with Free Parking
Ballwin, MO
10% off
Price is CA $593
CA $593
CA $5,398 total
CA $5,398 total
includes taxes & fees
Image gallery for Spacious Home w/ King bed! Fenced Yard
9.29.2 out of 10 rating
Wonderful
(35 reviews)
Spacious Home w/ King bed! Fenced Yard
St. Louis, MO
5% off
Price is CA $256
CA $256
CA $2,151 total
CA $2,151 total
includes taxes & fees
Image gallery for Cozy Saint Louis Cottage near Major Landmarks
1010 out of 10 rating
Exceptional
(18 reviews)
Cozy Saint Louis Cottage near Major Landmarks
St. Louis, MO
19% off
Price is CA $140
CA $140
CA $1,278 total
CA $1,278 total
includes taxes & fees
Image gallery for Smoke Free!!The Rock House Bnb, StL. Centrally Located + Park. 8 person Max!
9.29.2 out of 10 rating
Wonderful
(7 reviews)
Smoke Free!!The Rock House Bnb, StL. Centrally Located + Park. 8 person Max!
St. Louis, MO
23% off
Price is CA $208
CA $208
CA $1,855 total
CA $1,855 total
includes taxes & fees
Image gallery for Elegant Minimalist Gem w/ Private backyard, W/D
1010 out of 10 rating
Exceptional
(12 reviews)
Elegant Minimalist Gem w/ Private backyard, W/D
St. Louis, MO
10% off
Price is CA $106
CA $106
CA $1,084 total
CA $1,084 total
includes taxes & fees
Image gallery for Beautiful 2-bedroom house in awesome Ferguson .Mo with WiFi
1010 out of 10 rating
Exceptional
(6 reviews)
Beautiful 2-bedroom house in awesome Ferguson .Mo with WiFi
Ferguson, MO
5% off
Price is CA $261
CA $261
CA $2,281 total
CA $2,281 total
includes taxes & fees
Image gallery for Charming 2-Bed Brownstone in The Heart of New Town
1010 out of 10 rating
Exceptional
(12 reviews)
Charming 2-Bed Brownstone in The Heart of New Town
St. Charles, MO
10% off
Price is CA $272
CA $272
CA $2,318 total
CA $2,318 total
includes taxes & fees
Find spaces that suit your style
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Find the best place to stay - James S. McDonnell Prologue Room
The St. Charles Guest House, lovely historic home, fun for families and groups
Sleeps 8 · 3 bedrooms · 2 bathrooms
1010 out of 10
Exceptionalexceptional
131 reviews(131 reviews)
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
Sleeps 4 · 2 bedrooms · 1 bathroom
1010 out of 10
Exceptionalexceptional
204 reviews(204 reviews)
☆BackYard BBQ Hidden Gem☆Perfect Location~Groups /Pets Welcome
Sleeps 16 · 4 bedrooms · 2 bathrooms
8.88.8 out of 10
Excellentexcellent
55 reviews(55 reviews)
St. Charles 1860's Gem - Sleeps 6!
Sleeps 6 · 2 bedrooms · 1 bathroom
9.89.8 out of 10
Exceptionalexceptional
113 reviews(113 reviews)
Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway
Sleeps 10 · 3 bedrooms · 1 bathroom
9.69.6 out of 10
Exceptionalexceptional
44 reviews(44 reviews)
Retro Ranch With Private Indoor Pool & Sauna <br>St Louis, MO
Sleeps 10 · 4 bedrooms · 3+ bathrooms
1010 out of 10
Exceptionalexceptional
237 reviews(237 reviews)
Top rated rentals - James S. McDonnell Prologue Room
Incredible Place for a large group
1010 out of 10
Exceptionalexceptional
22 reviews(22 reviews)
Family Getaway
1010 out of 10
Exceptionalexceptional
218 reviews(218 reviews)
Cozy apartment
1010 out of 10
Exceptionalexceptional
273 reviews(273 reviews)
Great place to stay!
1010 out of 10
Exceptionalexceptional
204 reviews(204 reviews)
Peace of mindOur Book with Confidence guarantee gives you 24/7 support
More quality timeFrom booking to staying, the whole process is simple and enjoyable
All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
More for lessMore space, more privacy, more amenities — more value